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- W2794395831 endingPage "5664" @default.
- W2794395831 startingPage "5655" @default.
- W2794395831 abstract "Abstract Central nervous system homeostasis is maintained by cellular barriers that protect the brain from external environmental changes and protect the CNS from harmful molecules and pathogens in the blood. Historically, for many years these barriers were thought of as immature, with limited functions, during brain development. In this review, we will present advances in the understanding of the barrier systems during development and evidence to show that in fact the barriers serve many important neurodevelopmental functions and that fetal and newborn brains are well protected. We will also discuss how ischaemic injury or systemic inflammation may breach the integrity of the barriers in the developing brain. image" @default.
- W2794395831 created "2018-03-29" @default.
- W2794395831 creator A5025202949 @default.
- W2794395831 creator A5030623189 @default.
- W2794395831 creator A5051325172 @default.
- W2794395831 date "2018-04-16" @default.
- W2794395831 modified "2023-10-17" @default.
- W2794395831 title "The myth of the immature barrier systems in the developing brain: role in perinatal brain injury" @default.
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- W2794395831 doi "https://doi.org/10.1113/jp274938" @default.
- W2794395831 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6265562" @default.
- W2794395831 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29528501" @default.
- W2794395831 hasPublicationYear "2018" @default.
- W2794395831 type Work @default.