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- W2794590198 abstract "Abstract:Microbiological & environmental factors reportedly either initiate or modulate the course of periodontal diseases. But theresponse to these factors especially environmental is dependent on the patient’s genome. Thus variations in genetic factors areimplicated in periodontal diseases. Several study designs have been structured to establish the extent of the impact of geneticfactors in the causation as well as modulation of the course of periodontal diseases. There are several mechanisms which causealteration of the genetic factors leading to periodontal pathology. Most notable among them are polymorphisms of severalgenetic factors such as interleukin-1, tumour necrosis factor gene etc. But the exploration of the “master gene” responsible forperiodontal disease in an otherwise healthy individual still continues. No doubt evidence till date suggests that periodontaldisease is a complex multifactorial interaction but it is actually the genes which hold the key to unearthing hidden answers asthey are truly the cogs and gears of our system." @default.
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- W2794590198 date "2017-11-01" @default.
- W2794590198 modified "2023-09-22" @default.
- W2794590198 title "When cogs and gears fail- role of genetics in periodontal diseases" @default.
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