FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2794656411> ?p ?o ?g. }

• W2794656411 endingPage "iv12" @default.
• W2794656411 startingPage "iv6" @default.
• W2794656411 abstract "We assessed the potential role of T2Candida MR (T2MR) and serological biomarkers [β-d-glucan (BDG) or Candida albicans germ tube antibodies (CAGTA)], alone or in combination with standard cultures, for identifying patients with suspected invasive candidiasis (IC), who may benefit from maintaining antifungal therapy. Prospective observational multicentre study including all adult patients receiving empirical antifungal therapy for suspected IC, from January to June 2017. CAGTA, BDG and T2MR were determined at baseline and at +2 and +4 days after enrolment. Primary endpoint was the diagnostic value of CAGTA, BDG and T2MR, alone or in combination with standard culture, to predict diagnosis of IC and/or mortality in the first 7 days after starting antifungal therapy (poor outcome). Overall, 14/49 patients (28.6%) had a poor outcome (7 died within the first 7 days of antifungal therapy, whereas 7 ended with a diagnosis of IC). CAGTA [3/14 (21.4%) versus 8/35 (22.9%), P = 1] and BDG [8/14 (57.1%) versus 17/35 (48.6%), P = 0.75] results were similar in poor- and good-outcome patients. Conversely, a positive T2MR was associated with a higher risk of poor outcome [5/14 (35.7%) versus 0/35 (0.0%) P = 0.0001]. Specificity and positive predictive value of a positive T2MR for predicting poor outcome were both 100%, with a negative predictive value of 79.6%. After testing the combinations of biomarkers/standard cultures and T2MR/standard cultures, the combination of T2MR/standard cultures showed a high capacity to discriminate patients with poor outcome from those with good clinical evolution. T2MR may be of significant utility to identify patients who may benefit from maintaining antifungal therapy." @default.
• W2794656411 created "2018-04-06" @default.
• W2794656411 creator A5009198871 @default.
• W2794656411 creator A5016258231 @default.
• W2794656411 creator A5027824735 @default.
• W2794656411 creator A5039116288 @default.
• W2794656411 creator A5041412660 @default.
• W2794656411 creator A5041818001 @default.
• W2794656411 creator A5044281244 @default.
• W2794656411 creator A5046030731 @default.
• W2794656411 creator A5047559611 @default.
• W2794656411 creator A5049032617 @default.
• W2794656411 creator A5055627331 @default.
• W2794656411 creator A5055950037 @default.
• W2794656411 creator A5056525924 @default.
• W2794656411 creator A5062363608 @default.
• W2794656411 creator A5071487615 @default.
• W2794656411 creator A5075620145 @default.
• W2794656411 date "2018-03-01" @default.
• W2794656411 modified "2023-10-17" @default.
• W2794656411 title "T2Candida MR as a predictor of outcome in patients with suspected invasive candidiasis starting empirical antifungal treatment: a prospective pilot study" @default.
• W2794656411 cites W1515218780 @default.
• W2794656411 cites W1791388410 @default.
• W2794656411 cites W1886132783 @default.
• W2794656411 cites W1946090000 @default.
• W2794656411 cites W1995287041 @default.
• W2794656411 cites W1999241590 @default.
• W2794656411 cites W2044003032 @default.
• W2794656411 cites W2056588441 @default.
• W2794656411 cites W2077307323 @default.
• W2794656411 cites W2080363965 @default.
• W2794656411 cites W2087209268 @default.
• W2794656411 cites W2090630408 @default.
• W2794656411 cites W2093767199 @default.
• W2794656411 cites W2110912679 @default.
• W2794656411 cites W2112046323 @default.
• W2794656411 cites W2113002556 @default.
• W2794656411 cites W2133663142 @default.
• W2794656411 cites W2148012049 @default.
• W2794656411 cites W2166362951 @default.
• W2794656411 cites W2166734004 @default.
• W2794656411 cites W2170063898 @default.
• W2794656411 cites W2234667003 @default.
• W2794656411 cites W2260819425 @default.
• W2794656411 cites W2409288822 @default.
• W2794656411 cites W2527881422 @default.
• W2794656411 cites W2603754039 @default.
• W2794656411 cites W4246609299 @default.
• W2794656411 cites W4249751692 @default.
• W2794656411 doi "https://doi.org/10.1093/jac/dky047" @default.
• W2794656411 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30107468" @default.
• W2794656411 hasPublicationYear "2018" @default.
• W2794656411 type Work @default.
• W2794656411 sameAs 2794656411 @default.
• W2794656411 citedByCount "45" @default.
• W2794656411 countsByYear W27946564112018 @default.
• W2794656411 countsByYear W27946564112019 @default.
• W2794656411 countsByYear W27946564112020 @default.
• W2794656411 countsByYear W27946564112021 @default.
• W2794656411 countsByYear W27946564112022 @default.
• W2794656411 countsByYear W27946564112023 @default.
• W2794656411 crossrefType "journal-article" @default.
• W2794656411 hasAuthorship W2794656411A5009198871 @default.
• W2794656411 hasAuthorship W2794656411A5016258231 @default.
• W2794656411 hasAuthorship W2794656411A5027824735 @default.
• W2794656411 hasAuthorship W2794656411A5039116288 @default.
• W2794656411 hasAuthorship W2794656411A5041412660 @default.
• W2794656411 hasAuthorship W2794656411A5041818001 @default.
• W2794656411 hasAuthorship W2794656411A5044281244 @default.
• W2794656411 hasAuthorship W2794656411A5046030731 @default.
• W2794656411 hasAuthorship W2794656411A5047559611 @default.
• W2794656411 hasAuthorship W2794656411A5049032617 @default.
• W2794656411 hasAuthorship W2794656411A5055627331 @default.
• W2794656411 hasAuthorship W2794656411A5055950037 @default.
• W2794656411 hasAuthorship W2794656411A5056525924 @default.
• W2794656411 hasAuthorship W2794656411A5062363608 @default.
• W2794656411 hasAuthorship W2794656411A5071487615 @default.
• W2794656411 hasAuthorship W2794656411A5075620145 @default.
• W2794656411 hasBestOaLocation W27946564111 @default.
• W2794656411 hasConcept C126322002 @default.
• W2794656411 hasConcept C159654299 @default.
• W2794656411 hasConcept C16005928 @default.
• W2794656411 hasConcept C188816634 @default.
• W2794656411 hasConcept C203014093 @default.
• W2794656411 hasConcept C23131810 @default.
• W2794656411 hasConcept C2779548794 @default.
• W2794656411 hasConcept C2780161414 @default.
• W2794656411 hasConcept C2780651595 @default.
• W2794656411 hasConcept C2780917455 @default.
• W2794656411 hasConcept C45189115 @default.
• W2794656411 hasConcept C71924100 @default.
• W2794656411 hasConcept C86803240 @default.
• W2794656411 hasConcept C89423630 @default.
• W2794656411 hasConceptScore W2794656411C126322002 @default.
• W2794656411 hasConceptScore W2794656411C159654299 @default.
• W2794656411 hasConceptScore W2794656411C16005928 @default.
• W2794656411 hasConceptScore W2794656411C188816634 @default.
• W2794656411 hasConceptScore W2794656411C203014093 @default.

• next