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- W2794824834 abstract "Previous studies have demonstrated that donor-derived cell-free DNA (dd-cfDNA) found in circulating blood of transplant recipients may serve as a non-invasive biomarker of allograft rejection. The D-OAR study was undertaken to characterize the performance of dd-cfDNA in heart transplant recipients who are receiving rejection surveillance with gene expression profiling (GEP) as part of their standard care. To better interpret the clinical meaning of dd-cfDNA, it is essential to understand the biological variation of this biomarker in stable healthy recipients. This planned report will define the threshold of dd-cfDNA for rejection and will also establish the biological variation and clinical reference intervals of dd-cfDNA in heart transplant recipients using an analytically validated assay." @default.
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- W2794824834 date "2018-04-01" @default.
- W2794824834 modified "2023-09-27" @default.
- W2794824834 title "Donor-Derived Cell-Free DNA in D-OAR, a Real World, Clinical Use Heart Transplant Population" @default.
- W2794824834 doi "https://doi.org/10.1016/j.healun.2018.01.362" @default.
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