FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2794937418> ?p ?o ?g. }

• W2794937418 abstract "Background: Clostridioides difficile infection (CDI) is an important cause of morbidity and mortality among hospitalized patients. In China, however, hospital staff do not routinely test for CDI, leading to under-diagnosis and poor patient outcomes. Locally generated CDI data can help assess the magnitude of the problem and strengthen approaches for CDI prevention and control. Methods: We prospectively monitored hospital-onset hospital-associated (HOHA) CDI in four intensive care units (ICUs) from June 2013 to September 2014 in a large teaching hospital in China. We collected clinical information from all ICU patients with >3 episodes of diarrhea occurring within a 24-hour period at least 48 hours following admission (suspect case definition). Stool specimens were collected from all suspect cases of CDI and cultured for C. difficile. Polymerase chain reaction (PCR) was used to detect toxin genes from positive isolates; multi-locus sequence typing (MLST) was used for typing and identifying novel strains. We estimated the incidence rate as the number of HOHA CDI cases per 10,000 patient days; 95% confidence intervals were generated to assess rate differences between the four ICUs. Results: A total of 593 hospital-onset diarrhea patients met the suspect case definition during the study period. Of these, 47 patients (8%) were positive for C. difficile and toxin genes. The HOHA-CDI incidence rate was 14.08 cases per 10,000 patient days (95% CI: 10.47-18.57). Six patients with HOHA CDI died. ST54 (n = 14, 20%) was the most common type of HOHA-CDI strain circulating in the hospital during the study period and was linked to a temporal cluster (outbreak) involving two (NICU and GICU) of the four ICUs. Conclusion: HOHA-CDI occurs among ICU patients at this teaching hospital, supporting the importance of routine testing for CDI. Information on strain distribution can help detect CDI outbreaks. Detection of ST54 strain in a temporal cluster suggests possible gaps in infection control practices that should be investigated and addressed as needed." @default.
• W2794937418 created "2018-04-06" @default.
• W2794937418 creator A5010386617 @default.
• W2794937418 creator A5011411701 @default.
• W2794937418 creator A5026023085 @default.
• W2794937418 creator A5037750863 @default.
• W2794937418 creator A5045150831 @default.
• W2794937418 creator A5049383606 @default.
• W2794937418 creator A5057320824 @default.
• W2794937418 creator A5072776089 @default.
• W2794937418 creator A5077237908 @default.
• W2794937418 creator A5081715316 @default.
• W2794937418 date "2018-03-27" @default.
• W2794937418 modified "2023-10-14" @default.
• W2794937418 title "Incidence and Outbreak of Healthcare-Onset Healthcare-Associated Clostridioides difficile Infections Among Intensive Care Patients in a Large Teaching Hospital in China" @default.
• W2794937418 cites W1685880048 @default.
• W2794937418 cites W1945779440 @default.
• W2794937418 cites W1950271369 @default.
• W2794937418 cites W1967641292 @default.
• W2794937418 cites W2001093099 @default.
• W2794937418 cites W2006446060 @default.
• W2794937418 cites W2008719580 @default.
• W2794937418 cites W2013177030 @default.
• W2794937418 cites W2068021188 @default.
• W2794937418 cites W2074282438 @default.
• W2794937418 cites W2074586142 @default.
• W2794937418 cites W2078936504 @default.
• W2794937418 cites W2080594197 @default.
• W2794937418 cites W2094187389 @default.
• W2794937418 cites W2104491546 @default.
• W2794937418 cites W2108657897 @default.
• W2794937418 cites W2134665827 @default.
• W2794937418 cites W2166660180 @default.
• W2794937418 cites W2167097830 @default.
• W2794937418 cites W2225799478 @default.
• W2794937418 cites W2487600550 @default.
• W2794937418 cites W2528612573 @default.
• W2794937418 cites W2613226987 @default.
• W2794937418 doi "https://doi.org/10.3389/fmicb.2018.00566" @default.
• W2794937418 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5880889" @default.
• W2794937418 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29636739" @default.
• W2794937418 hasPublicationYear "2018" @default.
• W2794937418 type Work @default.
• W2794937418 sameAs 2794937418 @default.
• W2794937418 citedByCount "13" @default.
• W2794937418 countsByYear W27949374182019 @default.
• W2794937418 countsByYear W27949374182020 @default.
• W2794937418 countsByYear W27949374182021 @default.
• W2794937418 countsByYear W27949374182022 @default.
• W2794937418 countsByYear W27949374182023 @default.
• W2794937418 crossrefType "journal-article" @default.
• W2794937418 hasAuthorship W2794937418A5010386617 @default.
• W2794937418 hasAuthorship W2794937418A5011411701 @default.
• W2794937418 hasAuthorship W2794937418A5026023085 @default.
• W2794937418 hasAuthorship W2794937418A5037750863 @default.
• W2794937418 hasAuthorship W2794937418A5045150831 @default.
• W2794937418 hasAuthorship W2794937418A5049383606 @default.
• W2794937418 hasAuthorship W2794937418A5057320824 @default.
• W2794937418 hasAuthorship W2794937418A5072776089 @default.
• W2794937418 hasAuthorship W2794937418A5077237908 @default.
• W2794937418 hasAuthorship W2794937418A5081715316 @default.
• W2794937418 hasBestOaLocation W27949374181 @default.
• W2794937418 hasConcept C116675565 @default.
• W2794937418 hasConcept C120665830 @default.
• W2794937418 hasConcept C121332964 @default.
• W2794937418 hasConcept C126322002 @default.
• W2794937418 hasConcept C159047783 @default.
• W2794937418 hasConcept C166888038 @default.
• W2794937418 hasConcept C177713679 @default.
• W2794937418 hasConcept C187212893 @default.
• W2794937418 hasConcept C194828623 @default.
• W2794937418 hasConcept C2776376669 @default.
• W2794937418 hasConcept C2779802037 @default.
• W2794937418 hasConcept C2910067853 @default.
• W2794937418 hasConcept C2987404301 @default.
• W2794937418 hasConcept C2994496256 @default.
• W2794937418 hasConcept C501593827 @default.
• W2794937418 hasConcept C61511704 @default.
• W2794937418 hasConcept C71924100 @default.
• W2794937418 hasConcept C86803240 @default.
• W2794937418 hasConcept C89423630 @default.
• W2794937418 hasConceptScore W2794937418C116675565 @default.
• W2794937418 hasConceptScore W2794937418C120665830 @default.
• W2794937418 hasConceptScore W2794937418C121332964 @default.
• W2794937418 hasConceptScore W2794937418C126322002 @default.
• W2794937418 hasConceptScore W2794937418C159047783 @default.
• W2794937418 hasConceptScore W2794937418C166888038 @default.
• W2794937418 hasConceptScore W2794937418C177713679 @default.
• W2794937418 hasConceptScore W2794937418C187212893 @default.
• W2794937418 hasConceptScore W2794937418C194828623 @default.
• W2794937418 hasConceptScore W2794937418C2776376669 @default.
• W2794937418 hasConceptScore W2794937418C2779802037 @default.
• W2794937418 hasConceptScore W2794937418C2910067853 @default.
• W2794937418 hasConceptScore W2794937418C2987404301 @default.
• W2794937418 hasConceptScore W2794937418C2994496256 @default.
• W2794937418 hasConceptScore W2794937418C501593827 @default.
• W2794937418 hasConceptScore W2794937418C61511704 @default.
• W2794937418 hasConceptScore W2794937418C71924100 @default.
• W2794937418 hasConceptScore W2794937418C86803240 @default.
• W2794937418 hasConceptScore W2794937418C89423630 @default.

• next