FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2795201991> ?p ?o ?g. }

• W2795201991 abstract "Sinomenine is a monomer extracted from the traditional Chinese medicine plant Sabia japonica, which possesses several pharmacological properties including prominent abirritation, mitigation, anti-inflammation, immune suppression, cough relief, stimulation of histamine release, decrease in blood pressure and antiarrhythmia. Sinomenine is clinically employed to treat rheumatic disease. To investigate the impact of combined sinomenine treatment with acupuncture on the progression of arthritis and explore the potential underlying molecular mechanisms, the present study analyzed a collagen-induced arthritis model. Results from the combined curative (CC) treatment group (combined treatment with sinomenine and acupuncture) demonstrated a decrease in volume changes and arthritis score changes within rat paws, and increased the overall body weight in arthritic rats. CC treatment significantly decreased tumor necrosis factor α, interleukin (IL)-6, IL-1β and IL-8 serum levels in arthritic rats. CC treatment significantly increased superoxide dismutase and inhibited malondialdehyde levels in arthritic rats. The protein expression of cyclooxygenase-2, inducible nitric oxide synthase, matrix metalloproteinase (MMP)2 and MMP9 in arthritic rats was suppressed owing to CC treatment. Finally, nuclear factor κB and phosphorylated p38 mitogen-activated protein kinase (MAPK) protein expression in arthritic rats were also suppressed following CC treatment. The results indicate that the combined treatment of sinomenine and acupuncture on collagen-induced arthritis takes effect through the nuclear factor κB and MAPK signaling pathway." @default.
• W2795201991 created "2018-04-06" @default.
• W2795201991 creator A5052676364 @default.
• W2795201991 creator A5066867197 @default.
• W2795201991 creator A5068538410 @default.
• W2795201991 creator A5070561064 @default.
• W2795201991 date "2018-03-30" @default.
• W2795201991 modified "2023-09-29" @default.
• W2795201991 title "Combined treatment with sinomenine and acupuncture on collagen‑induced arthritis through the NF‑κB and MAPK signaling pathway" @default.
• W2795201991 cites W1196444374 @default.
• W2795201991 cites W1264104737 @default.
• W2795201991 cites W153320833 @default.
• W2795201991 cites W1564862190 @default.
• W2795201991 cites W1951356170 @default.
• W2795201991 cites W1985677684 @default.
• W2795201991 cites W1990670189 @default.
• W2795201991 cites W2039388891 @default.
• W2795201991 cites W2051450213 @default.
• W2795201991 cites W2058337748 @default.
• W2795201991 cites W2071011604 @default.
• W2795201991 cites W2089065105 @default.
• W2795201991 cites W2101387400 @default.
• W2795201991 cites W2110631174 @default.
• W2795201991 cites W2112046799 @default.
• W2795201991 cites W2120290065 @default.
• W2795201991 cites W2152936118 @default.
• W2795201991 cites W2235800732 @default.
• W2795201991 cites W2265100331 @default.
• W2795201991 cites W2284157696 @default.
• W2795201991 cites W2296697021 @default.
• W2795201991 cites W2316985585 @default.
• W2795201991 cites W2321748383 @default.
• W2795201991 cites W2393952933 @default.
• W2795201991 cites W2402604959 @default.
• W2795201991 cites W2435643317 @default.
• W2795201991 cites W2560003214 @default.
• W2795201991 cites W2607914879 @default.
• W2795201991 cites W2767476022 @default.
• W2795201991 cites W2782964087 @default.
• W2795201991 doi "https://doi.org/10.3892/ol.2018.8394" @default.
• W2795201991 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5950530" @default.
• W2795201991 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29805616" @default.
• W2795201991 hasPublicationYear "2018" @default.
• W2795201991 type Work @default.
• W2795201991 sameAs 2795201991 @default.
• W2795201991 citedByCount "7" @default.
• W2795201991 countsByYear W27952019912018 @default.
• W2795201991 countsByYear W27952019912021 @default.
• W2795201991 countsByYear W27952019912022 @default.
• W2795201991 crossrefType "journal-article" @default.
• W2795201991 hasAuthorship W2795201991A5052676364 @default.
• W2795201991 hasAuthorship W2795201991A5066867197 @default.
• W2795201991 hasAuthorship W2795201991A5068538410 @default.
• W2795201991 hasAuthorship W2795201991A5070561064 @default.
• W2795201991 hasBestOaLocation W27952019911 @default.
• W2795201991 hasConcept C121608353 @default.
• W2795201991 hasConcept C126322002 @default.
• W2795201991 hasConcept C142724271 @default.
• W2795201991 hasConcept C17991360 @default.
• W2795201991 hasConcept C185592680 @default.
• W2795201991 hasConcept C203014093 @default.
• W2795201991 hasConcept C204787440 @default.
• W2795201991 hasConcept C2776202274 @default.
• W2795201991 hasConcept C2777077863 @default.
• W2795201991 hasConcept C2777622882 @default.
• W2795201991 hasConcept C2777662524 @default.
• W2795201991 hasConcept C2779504368 @default.
• W2795201991 hasConcept C2781018059 @default.
• W2795201991 hasConcept C29537977 @default.
• W2795201991 hasConcept C51551487 @default.
• W2795201991 hasConcept C519581460 @default.
• W2795201991 hasConcept C55493867 @default.
• W2795201991 hasConcept C56837625 @default.
• W2795201991 hasConcept C57074206 @default.
• W2795201991 hasConcept C62478195 @default.
• W2795201991 hasConcept C71924100 @default.
• W2795201991 hasConcept C98274493 @default.
• W2795201991 hasConceptScore W2795201991C121608353 @default.
• W2795201991 hasConceptScore W2795201991C126322002 @default.
• W2795201991 hasConceptScore W2795201991C142724271 @default.
• W2795201991 hasConceptScore W2795201991C17991360 @default.
• W2795201991 hasConceptScore W2795201991C185592680 @default.
• W2795201991 hasConceptScore W2795201991C203014093 @default.
• W2795201991 hasConceptScore W2795201991C204787440 @default.
• W2795201991 hasConceptScore W2795201991C2776202274 @default.
• W2795201991 hasConceptScore W2795201991C2777077863 @default.
• W2795201991 hasConceptScore W2795201991C2777622882 @default.
• W2795201991 hasConceptScore W2795201991C2777662524 @default.
• W2795201991 hasConceptScore W2795201991C2779504368 @default.
• W2795201991 hasConceptScore W2795201991C2781018059 @default.
• W2795201991 hasConceptScore W2795201991C29537977 @default.
• W2795201991 hasConceptScore W2795201991C51551487 @default.
• W2795201991 hasConceptScore W2795201991C519581460 @default.
• W2795201991 hasConceptScore W2795201991C55493867 @default.
• W2795201991 hasConceptScore W2795201991C56837625 @default.
• W2795201991 hasConceptScore W2795201991C57074206 @default.
• W2795201991 hasConceptScore W2795201991C62478195 @default.
• W2795201991 hasConceptScore W2795201991C71924100 @default.
• W2795201991 hasConceptScore W2795201991C98274493 @default.
• W2795201991 hasLocation W27952019911 @default.

• next