Matches in SemOpenAlex for { <https://semopenalex.org/work/W2795271943> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2795271943 endingPage "724" @default.
- W2795271943 startingPage "718" @default.
- W2795271943 abstract "Patients with submucosal invasive colorectal cancer (SM-CRC) treated with endoscopic resection who are at low risk of lymph node metastasis and local recurrence may be followed up with observation alone, while additional surgery is recommended for those with high risk features. However, the long-term outcomes that these strategies offer are still unclear. The objective of our study was to retrospectively evaluate the long-term outcomes of patients with SM-CRC managed with endoscopic resection.We retrospectively analyzed all patients with SM-CRC treated by endoscopic resection at six institutions between 2000 and 2007. SM-CRCs with (i) negative vertical margin, (ii) well or moderately differentiated adenocarcinoma, (iii) absence of lymphovascular invasion, and (iv) invasion depth < 1000 µm were classified as low risk. Patients with SM-CRCs without these characteristics were classified as high risk. Outcomes were assessed by 5-year recurrence-free survival (RFS) and recurrence rate.During the study period, 428 patients with SM-CRC (low risk, 126; high risk, 302) who underwent endoscopic resection as their first treatment were enrolled (median follow-up 61 months). Among the 120 patients with low risk features treated by endoscopic resection alone, the 5-year RFS and recurrence rates were 98 % and 0.8 %, respectively. Of the 302 patients with high risk features, 196 underwent additional surgery and 106 were managed with endoscopic resection alone. For those who underwent additional surgery, the 5-year RFS and recurrence rates were 97 % and 3.6 %, respectively. Among the 106 patients managed with endoscopic resection alone, RFS and recurrence rates were 89 % (P < 0.05 vs. low risk patients treated by endoscopic resection alone) and 6.6 % (P < 0.05), respectively.Endoscopic resection alone is adequate for the management of patients with SM-CRC and low risk features. However, in those patients with SM-CRC and high risk features, surgery should be considered in addition to endoscopic resection." @default.
- W2795271943 created "2018-04-06" @default.
- W2795271943 creator A5001801008 @default.
- W2795271943 creator A5006603221 @default.
- W2795271943 creator A5012322950 @default.
- W2795271943 creator A5012400291 @default.
- W2795271943 creator A5015262464 @default.
- W2795271943 creator A5017848730 @default.
- W2795271943 creator A5035520250 @default.
- W2795271943 creator A5046786824 @default.
- W2795271943 creator A5048834130 @default.
- W2795271943 creator A5062602632 @default.
- W2795271943 creator A5068544540 @default.
- W2795271943 creator A5069123778 @default.
- W2795271943 creator A5071673879 @default.
- W2795271943 creator A5072568857 @default.
- W2795271943 creator A5073742569 @default.
- W2795271943 date "2013-08-05" @default.
- W2795271943 modified "2023-09-23" @default.
- W2795271943 title "A large-scale multicenter study of long-term outcomes after endoscopic resection for submucosal invasive colorectal cancer" @default.
- W2795271943 doi "https://doi.org/10.1055/s-0033-1344234" @default.
- W2795271943 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23918621" @default.
- W2795271943 hasPublicationYear "2013" @default.
- W2795271943 type Work @default.
- W2795271943 sameAs 2795271943 @default.
- W2795271943 citedByCount "115" @default.
- W2795271943 countsByYear W27952719432013 @default.
- W2795271943 countsByYear W27952719432014 @default.
- W2795271943 countsByYear W27952719432015 @default.
- W2795271943 countsByYear W27952719432016 @default.
- W2795271943 countsByYear W27952719432017 @default.
- W2795271943 countsByYear W27952719432018 @default.
- W2795271943 countsByYear W27952719432019 @default.
- W2795271943 countsByYear W27952719432020 @default.
- W2795271943 countsByYear W27952719432021 @default.
- W2795271943 countsByYear W27952719432022 @default.
- W2795271943 countsByYear W27952719432023 @default.
- W2795271943 crossrefType "journal-article" @default.
- W2795271943 hasAuthorship W2795271943A5001801008 @default.
- W2795271943 hasAuthorship W2795271943A5006603221 @default.
- W2795271943 hasAuthorship W2795271943A5012322950 @default.
- W2795271943 hasAuthorship W2795271943A5012400291 @default.
- W2795271943 hasAuthorship W2795271943A5015262464 @default.
- W2795271943 hasAuthorship W2795271943A5017848730 @default.
- W2795271943 hasAuthorship W2795271943A5035520250 @default.
- W2795271943 hasAuthorship W2795271943A5046786824 @default.
- W2795271943 hasAuthorship W2795271943A5048834130 @default.
- W2795271943 hasAuthorship W2795271943A5062602632 @default.
- W2795271943 hasAuthorship W2795271943A5068544540 @default.
- W2795271943 hasAuthorship W2795271943A5069123778 @default.
- W2795271943 hasAuthorship W2795271943A5071673879 @default.
- W2795271943 hasAuthorship W2795271943A5072568857 @default.
- W2795271943 hasAuthorship W2795271943A5073742569 @default.
- W2795271943 hasConcept C121608353 @default.
- W2795271943 hasConcept C126322002 @default.
- W2795271943 hasConcept C141071460 @default.
- W2795271943 hasConcept C159110652 @default.
- W2795271943 hasConcept C167135981 @default.
- W2795271943 hasConcept C2778132481 @default.
- W2795271943 hasConcept C2778451229 @default.
- W2795271943 hasConcept C2778740770 @default.
- W2795271943 hasConcept C2778866283 @default.
- W2795271943 hasConcept C2779013556 @default.
- W2795271943 hasConcept C526805850 @default.
- W2795271943 hasConcept C71924100 @default.
- W2795271943 hasConceptScore W2795271943C121608353 @default.
- W2795271943 hasConceptScore W2795271943C126322002 @default.
- W2795271943 hasConceptScore W2795271943C141071460 @default.
- W2795271943 hasConceptScore W2795271943C159110652 @default.
- W2795271943 hasConceptScore W2795271943C167135981 @default.
- W2795271943 hasConceptScore W2795271943C2778132481 @default.
- W2795271943 hasConceptScore W2795271943C2778451229 @default.
- W2795271943 hasConceptScore W2795271943C2778740770 @default.
- W2795271943 hasConceptScore W2795271943C2778866283 @default.
- W2795271943 hasConceptScore W2795271943C2779013556 @default.
- W2795271943 hasConceptScore W2795271943C526805850 @default.
- W2795271943 hasConceptScore W2795271943C71924100 @default.
- W2795271943 hasIssue "09" @default.
- W2795271943 hasLocation W27952719431 @default.
- W2795271943 hasLocation W27952719432 @default.
- W2795271943 hasOpenAccess W2795271943 @default.
- W2795271943 hasPrimaryLocation W27952719431 @default.
- W2795271943 hasRelatedWork W1888686819 @default.
- W2795271943 hasRelatedWork W1970423756 @default.
- W2795271943 hasRelatedWork W1983331961 @default.
- W2795271943 hasRelatedWork W2105346473 @default.
- W2795271943 hasRelatedWork W2150928782 @default.
- W2795271943 hasRelatedWork W2327949229 @default.
- W2795271943 hasRelatedWork W2947833179 @default.
- W2795271943 hasRelatedWork W3009689500 @default.
- W2795271943 hasRelatedWork W3112333798 @default.
- W2795271943 hasRelatedWork W87691106 @default.
- W2795271943 hasVolume "45" @default.
- W2795271943 isParatext "false" @default.
- W2795271943 isRetracted "false" @default.
- W2795271943 magId "2795271943" @default.
- W2795271943 workType "article" @default.