Matches in SemOpenAlex for { <https://semopenalex.org/work/W2795310028> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2795310028 abstract "Metabolic syndrome (MetS) and obesity have increasingly been reported in survivors of childhood cancer. Osteopontin (OPN) is primarily synthesized in adipose tissue and is thought to have a role in obesity and the development of insulin resistance (IR). The aim of this study was to investigate the frequency of MetS in survivors of acute lymphoblastic leukemia (ALL) and to establish the relationship between serum OPN levels and anthropometric measurements and glucose metabolism.A total 50 survivors of ALL (median age: 10.5 years; post-treatment interval 4.54 ± 2.48 years), and 20 healthy children (median age: 11 years) were included in the study. Anthropometric measurements were taken, and serum glucose, insulin, homeostasis model assessment and IR index (HOMA-IR index), lipoprotein, thyroid hormone levels, and OPN levels were measured.Twenty-one (42%) survivors were overweight/obese, 2 (5.1%) survivors had MetS, 7 (14%) survivors had IR, and 19 (38%) survivors had dyslipidemia. Fasting insulin levels and HOMA-IR of the overweight/obese survivors were significantly higher than those of the normal-weight survivors (p < 0.05 and p < 0.01) and control group (p < 0.01 and p < 0.01). The serum OPN level was significantly lower in the overweight/obese survivor than in the normal-weight survivor and control group (37.42 ng/mL [range, 27.32-62.07], 69.02 ng/mL [range, 40.29-88.21], and 85.7 ng/mL [range 67.7-102.3]; p < 0.01, p < 0.001, respectively). Serum OPN levels were inversely correlated with anthropometric measurements and HOMA-IR index in all the subjects.Our results showed that obesity and IR are associated with decreased serum OPN levels in childhood survivors of ALL." @default.
- W2795310028 created "2018-04-06" @default.
- W2795310028 creator A5006803754 @default.
- W2795310028 creator A5041407831 @default.
- W2795310028 creator A5060608237 @default.
- W2795310028 creator A5069240571 @default.
- W2795310028 creator A5073991987 @default.
- W2795310028 creator A5086332937 @default.
- W2795310028 date "2018-08-01" @default.
- W2795310028 modified "2023-09-24" @default.
- W2795310028 title "The Frequency of Metabolic Syndrome and Serum Osteopontin Levels in Survivors of Childhood Acute Lymphoblastic Leukemia" @default.
- W2795310028 cites W1969611762 @default.
- W2795310028 cites W1977289240 @default.
- W2795310028 cites W1982967084 @default.
- W2795310028 cites W1997077836 @default.
- W2795310028 cites W1997697459 @default.
- W2795310028 cites W1998301770 @default.
- W2795310028 cites W2008283534 @default.
- W2795310028 cites W2013780938 @default.
- W2795310028 cites W2024305859 @default.
- W2795310028 cites W2025628030 @default.
- W2795310028 cites W2031256781 @default.
- W2795310028 cites W2031935858 @default.
- W2795310028 cites W2033817226 @default.
- W2795310028 cites W2037139749 @default.
- W2795310028 cites W2063923885 @default.
- W2795310028 cites W2074551005 @default.
- W2795310028 cites W2079746106 @default.
- W2795310028 cites W2087696761 @default.
- W2795310028 cites W2088758051 @default.
- W2795310028 cites W2096574031 @default.
- W2795310028 cites W2113525441 @default.
- W2795310028 cites W2130774485 @default.
- W2795310028 cites W2139651989 @default.
- W2795310028 cites W2140409181 @default.
- W2795310028 cites W2142732613 @default.
- W2795310028 cites W2145796003 @default.
- W2795310028 cites W2149552945 @default.
- W2795310028 cites W2332369401 @default.
- W2795310028 cites W2396402306 @default.
- W2795310028 cites W2514013076 @default.
- W2795310028 cites W2516159575 @default.
- W2795310028 cites W2593685779 @default.
- W2795310028 cites W59010850 @default.
- W2795310028 doi "https://doi.org/10.1089/jayao.2017.0129" @default.
- W2795310028 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29641359" @default.
- W2795310028 hasPublicationYear "2018" @default.
- W2795310028 type Work @default.
- W2795310028 sameAs 2795310028 @default.
- W2795310028 citedByCount "3" @default.
- W2795310028 countsByYear W27953100282020 @default.
- W2795310028 countsByYear W27953100282021 @default.
- W2795310028 countsByYear W27953100282022 @default.
- W2795310028 crossrefType "journal-article" @default.
- W2795310028 hasAuthorship W2795310028A5006803754 @default.
- W2795310028 hasAuthorship W2795310028A5041407831 @default.
- W2795310028 hasAuthorship W2795310028A5060608237 @default.
- W2795310028 hasAuthorship W2795310028A5069240571 @default.
- W2795310028 hasAuthorship W2795310028A5073991987 @default.
- W2795310028 hasAuthorship W2795310028A5086332937 @default.
- W2795310028 hasConcept C126322002 @default.
- W2795310028 hasConcept C134018914 @default.
- W2795310028 hasConcept C2777391703 @default.
- W2795310028 hasConcept C2778096610 @default.
- W2795310028 hasConcept C2779422640 @default.
- W2795310028 hasConcept C2780221984 @default.
- W2795310028 hasConcept C2780578515 @default.
- W2795310028 hasConcept C2780586474 @default.
- W2795310028 hasConcept C511355011 @default.
- W2795310028 hasConcept C61427482 @default.
- W2795310028 hasConcept C71924100 @default.
- W2795310028 hasConceptScore W2795310028C126322002 @default.
- W2795310028 hasConceptScore W2795310028C134018914 @default.
- W2795310028 hasConceptScore W2795310028C2777391703 @default.
- W2795310028 hasConceptScore W2795310028C2778096610 @default.
- W2795310028 hasConceptScore W2795310028C2779422640 @default.
- W2795310028 hasConceptScore W2795310028C2780221984 @default.
- W2795310028 hasConceptScore W2795310028C2780578515 @default.
- W2795310028 hasConceptScore W2795310028C2780586474 @default.
- W2795310028 hasConceptScore W2795310028C511355011 @default.
- W2795310028 hasConceptScore W2795310028C61427482 @default.
- W2795310028 hasConceptScore W2795310028C71924100 @default.
- W2795310028 hasLocation W27953100281 @default.
- W2795310028 hasLocation W27953100282 @default.
- W2795310028 hasOpenAccess W2795310028 @default.
- W2795310028 hasPrimaryLocation W27953100281 @default.
- W2795310028 hasRelatedWork W1847703394 @default.
- W2795310028 hasRelatedWork W2013490181 @default.
- W2795310028 hasRelatedWork W2022354674 @default.
- W2795310028 hasRelatedWork W2045668028 @default.
- W2795310028 hasRelatedWork W2064511809 @default.
- W2795310028 hasRelatedWork W2132661486 @default.
- W2795310028 hasRelatedWork W2156658406 @default.
- W2795310028 hasRelatedWork W2171538978 @default.
- W2795310028 hasRelatedWork W4214663700 @default.
- W2795310028 hasRelatedWork W963710140 @default.
- W2795310028 isParatext "false" @default.
- W2795310028 isRetracted "false" @default.
- W2795310028 magId "2795310028" @default.
- W2795310028 workType "article" @default.