Matches in SemOpenAlex for { <https://semopenalex.org/work/W2795419113> ?p ?o ?g. }
- W2795419113 endingPage "969" @default.
- W2795419113 startingPage "959" @default.
- W2795419113 abstract "Abstract Hydroxyapatite (HAP) is a form of naturally occurring calcium apatite present in bone and tooth enamel. It is an important biomaterial with diverse biomedical applications such as a surface coating for metallic orthopedic implants. Synthesized pristine HAP has poor mechanical properties, inferior wear resistance and has limits for directly used in bone tissue engineering applications. To address these limitations, we synthesized a suitable orthopedic implant hybrid material (M-HAP/PCL/GO) by using positively charged calcium ions of mineralized HAP (M-HAP) combined with Polycaprolactone-negatively charged graphene oxide (PCL-GO). The successfully synthesized M-HAP/PCL/GO composite was comprehensively characterized by Fourier-transform infrared spectroscopy (FT-IR), powder X-ray diffraction (XRD) and field-emission scanning electron microscopy (FE-SEM). The micro-hardness technique was used to determine the mechanical strength of M-HAP (315 ± 4 Hv), M-HAP/GO (370 ± 3 Hv) and M-HAP/PCL/GO (455 ± 5 Hv). M-HAP/PCL/GO was also tested for its anti-bactericidal impact against Staphylococcus aureus and Escherichia coli. MG63 osteoblast cells cultured on the M-HAP/PCL/GO composite (10 mg/mL) coated sample, displayed outstanding viability after 3 and 5 days of incubation at pH 7.4, which indicated that the composite is suitable material for bone implants and induces the cell proliferation. It was also tested in vivo in Wistar rats and was observably beneficial bone formation within 28 days post-implant operation. These tests proved that the M-HAP/PCL/GO composite can be considered as a prospective candidate for future bone implant applications." @default.
- W2795419113 created "2018-04-13" @default.
- W2795419113 creator A5013187197 @default.
- W2795419113 creator A5033073844 @default.
- W2795419113 creator A5050791133 @default.
- W2795419113 date "2018-09-01" @default.
- W2795419113 modified "2023-10-03" @default.
- W2795419113 title "In vitro and in vivo characterization of mineralized hydroxyapatite/polycaprolactone-graphene oxide based bioactive multifunctional coating on Ti alloy for bone implant applications" @default.
- W2795419113 cites W1847997506 @default.
- W2795419113 cites W1849148642 @default.
- W2795419113 cites W1877081723 @default.
- W2795419113 cites W1927966957 @default.
- W2795419113 cites W1979284372 @default.
- W2795419113 cites W1981551320 @default.
- W2795419113 cites W1991539602 @default.
- W2795419113 cites W2005982235 @default.
- W2795419113 cites W2009492770 @default.
- W2795419113 cites W2017065473 @default.
- W2795419113 cites W2027449052 @default.
- W2795419113 cites W2029069725 @default.
- W2795419113 cites W2042163001 @default.
- W2795419113 cites W2051091991 @default.
- W2795419113 cites W2059183822 @default.
- W2795419113 cites W2064417438 @default.
- W2795419113 cites W2070084694 @default.
- W2795419113 cites W2075370669 @default.
- W2795419113 cites W2076888350 @default.
- W2795419113 cites W2079327424 @default.
- W2795419113 cites W2079888824 @default.
- W2795419113 cites W2101977779 @default.
- W2795419113 cites W2122446638 @default.
- W2795419113 cites W2137981247 @default.
- W2795419113 cites W2153588940 @default.
- W2795419113 cites W2162565410 @default.
- W2795419113 cites W2167486241 @default.
- W2795419113 cites W2208836600 @default.
- W2795419113 cites W2327420122 @default.
- W2795419113 cites W2336350333 @default.
- W2795419113 cites W2414468034 @default.
- W2795419113 cites W2415524595 @default.
- W2795419113 cites W2481298415 @default.
- W2795419113 cites W2557291857 @default.
- W2795419113 cites W2566011071 @default.
- W2795419113 cites W2579293753 @default.
- W2795419113 cites W2582351151 @default.
- W2795419113 cites W2605931919 @default.
- W2795419113 cites W2732411541 @default.
- W2795419113 cites W2735218653 @default.
- W2795419113 cites W2770406195 @default.
- W2795419113 doi "https://doi.org/10.1016/j.arabjc.2018.03.020" @default.
- W2795419113 hasPublicationYear "2018" @default.
- W2795419113 type Work @default.
- W2795419113 sameAs 2795419113 @default.
- W2795419113 citedByCount "73" @default.
- W2795419113 countsByYear W27954191132018 @default.
- W2795419113 countsByYear W27954191132019 @default.
- W2795419113 countsByYear W27954191132020 @default.
- W2795419113 countsByYear W27954191132021 @default.
- W2795419113 countsByYear W27954191132022 @default.
- W2795419113 countsByYear W27954191132023 @default.
- W2795419113 crossrefType "journal-article" @default.
- W2795419113 hasAuthorship W2795419113A5013187197 @default.
- W2795419113 hasAuthorship W2795419113A5033073844 @default.
- W2795419113 hasAuthorship W2795419113A5050791133 @default.
- W2795419113 hasBestOaLocation W27954191131 @default.
- W2795419113 hasConcept C127413603 @default.
- W2795419113 hasConcept C136229726 @default.
- W2795419113 hasConcept C141071460 @default.
- W2795419113 hasConcept C150903083 @default.
- W2795419113 hasConcept C171250308 @default.
- W2795419113 hasConcept C178790620 @default.
- W2795419113 hasConcept C185592680 @default.
- W2795419113 hasConcept C192562407 @default.
- W2795419113 hasConcept C202751555 @default.
- W2795419113 hasConcept C207001950 @default.
- W2795419113 hasConcept C2779851234 @default.
- W2795419113 hasConcept C2779868350 @default.
- W2795419113 hasConcept C2780026712 @default.
- W2795419113 hasConcept C2780841128 @default.
- W2795419113 hasConcept C2781411149 @default.
- W2795419113 hasConcept C2781448156 @default.
- W2795419113 hasConcept C30080830 @default.
- W2795419113 hasConcept C42360764 @default.
- W2795419113 hasConcept C521977710 @default.
- W2795419113 hasConcept C55493867 @default.
- W2795419113 hasConcept C71924100 @default.
- W2795419113 hasConcept C86803240 @default.
- W2795419113 hasConceptScore W2795419113C127413603 @default.
- W2795419113 hasConceptScore W2795419113C136229726 @default.
- W2795419113 hasConceptScore W2795419113C141071460 @default.
- W2795419113 hasConceptScore W2795419113C150903083 @default.
- W2795419113 hasConceptScore W2795419113C171250308 @default.
- W2795419113 hasConceptScore W2795419113C178790620 @default.
- W2795419113 hasConceptScore W2795419113C185592680 @default.
- W2795419113 hasConceptScore W2795419113C192562407 @default.
- W2795419113 hasConceptScore W2795419113C202751555 @default.
- W2795419113 hasConceptScore W2795419113C207001950 @default.
- W2795419113 hasConceptScore W2795419113C2779851234 @default.