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• W2795470737 abstract "Nanopharmaceuticals aim at translating the unique features of nano-scale materials into therapeutic products and consequently their development relies critically on the progression in manufacturing technology to allow scalable processes complying with process economy and quality assurance. The relatively high failure rate in translational nanopharmaceutical research and development, with respect to new products on the market, is at least partly due to immature bottom-up manufacturing development and resulting sub-optimal control of quality attributes in nanopharmaceuticals. Recently, quality-oriented manufacturing of pharmaceuticals has undergone an unprecedented change toward process and product development interaction. In this context, Quality by Design (QbD) aims to integrate product and process development resulting in an increased number of product applications to regulatory agencies and stronger proprietary defense strategies of process-based products. Although QbD can be applied to essentially any production approach, microfluidic production offers particular opportunities for QbD-based manufacturing of nanopharmaceuticals. Microfluidics provides unique design flexibility, process control and parameter predictability, and also offers ample opportunities for modular production setups, allowing process feedback for continuously operating production and process control. The present review aims at outlining emerging opportunities in the synergistic implementation of QbD strategies and microfluidic production in contemporary development and manufacturing of nanopharmaceuticals. In doing so, aspects of design and development, but also technology management, are reviewed, as is the strategic role of these tools for aligning nanopharmaceutical innovation, development, and advanced industrialization in the broader pharmaceutical field." @default.
• W2795470737 created "2018-04-13" @default.
• W2795470737 creator A5018101817 @default.
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• W2795470737 creator A5061885471 @default.
• W2795470737 creator A5090244511 @default.
• W2795470737 date "2018-03-01" @default.
• W2795470737 modified "2023-10-14" @default.
• W2795470737 title "Transforming nanomedicine manufacturing toward Quality by Design and microfluidics" @default.
• W2795470737 cites W1535876276 @default.
• W2795470737 cites W1570637627 @default.
• W2795470737 cites W1786404767 @default.
• W2795470737 cites W1840805957 @default.
• W2795470737 cites W1969018013 @default.
• W2795470737 cites W1969641539 @default.
• W2795470737 cites W1970763651 @default.
• W2795470737 cites W1976928292 @default.
• W2795470737 cites W1977479596 @default.
• W2795470737 cites W1978094989 @default.
• W2795470737 cites W1978988431 @default.
• W2795470737 cites W1981883789 @default.
• W2795470737 cites W1983989992 @default.
• W2795470737 cites W1985392227 @default.
• W2795470737 cites W1989230986 @default.
• W2795470737 cites W1990568247 @default.
• W2795470737 cites W1993418313 @default.
• W2795470737 cites W1994031021 @default.
• W2795470737 cites W1996820263 @default.
• W2795470737 cites W1997187492 @default.
• W2795470737 cites W1999481657 @default.
• W2795470737 cites W2000924336 @default.
• W2795470737 cites W2004186868 @default.
• W2795470737 cites W2010898707 @default.
• W2795470737 cites W2013765163 @default.
• W2795470737 cites W2017827273 @default.
• W2795470737 cites W2018180334 @default.
• W2795470737 cites W2022288348 @default.
• W2795470737 cites W2024524719 @default.
• W2795470737 cites W2028279608 @default.
• W2795470737 cites W2035159723 @default.
• W2795470737 cites W2036443544 @default.
• W2795470737 cites W2037134420 @default.
• W2795470737 cites W2042249858 @default.
• W2795470737 cites W2044014417 @default.
• W2795470737 cites W2044598213 @default.
• W2795470737 cites W2057218780 @default.
• W2795470737 cites W2058865733 @default.
• W2795470737 cites W2064291338 @default.
• W2795470737 cites W2067796149 @default.
• W2795470737 cites W2071680657 @default.
• W2795470737 cites W2073591017 @default.
• W2795470737 cites W2080181678 @default.
• W2795470737 cites W2082219228 @default.
• W2795470737 cites W2082471725 @default.
• W2795470737 cites W2084264015 @default.
• W2795470737 cites W2089731238 @default.
• W2795470737 cites W2090168663 @default.
• W2795470737 cites W2115524611 @default.
• W2795470737 cites W2125329723 @default.
• W2795470737 cites W2130384225 @default.
• W2795470737 cites W2135486162 @default.
• W2795470737 cites W2145186138 @default.
• W2795470737 cites W2145368547 @default.
• W2795470737 cites W2146205672 @default.
• W2795470737 cites W2146431258 @default.
• W2795470737 cites W2149144667 @default.
• W2795470737 cites W2159312946 @default.
• W2795470737 cites W2160501566 @default.
• W2795470737 cites W2161004176 @default.
• W2795470737 cites W2163221573 @default.
• W2795470737 cites W2163882989 @default.
• W2795470737 cites W2164757273 @default.
• W2795470737 cites W2166043488 @default.
• W2795470737 cites W2167924652 @default.
• W2795470737 cites W2187929102 @default.
• W2795470737 cites W2295313671 @default.
• W2795470737 cites W2312592011 @default.
• W2795470737 cites W2344644350 @default.
• W2795470737 cites W2344850880 @default.
• W2795470737 cites W2421275313 @default.
• W2795470737 cites W2461143510 @default.
• W2795470737 cites W2510123569 @default.
• W2795470737 cites W2518588461 @default.
• W2795470737 cites W2518930990 @default.
• W2795470737 cites W2521436285 @default.
• W2795470737 cites W2521526894 @default.
• W2795470737 cites W2541324120 @default.
• W2795470737 cites W2551207187 @default.
• W2795470737 cites W2560374537 @default.
• W2795470737 cites W2568745304 @default.
• W2795470737 cites W2576217222 @default.
• W2795470737 cites W2584176612 @default.
• W2795470737 cites W2586737496 @default.
• W2795470737 cites W2586868429 @default.
• W2795470737 cites W2600897427 @default.
• W2795470737 cites W2616168161 @default.

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