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- W2795751330 abstract "A fluorescein based organic nanoparticles were prepared by using synthesized N-(3′,6′-dihydroxy-3-oxospiro[isoindoline-1,9′-xanthene]-2-yl)-2-hydroxybenzamide(FB). The interaction of series of metal ions with the FB nanoparticles (FBNPs) was investigated by means of fluorescence measurement. The selective and sensitive fluorescence enhancement was observed to FBNPs by the addition of Zn2+ ion in an aqueous medium. The interaction of FBNPs and Zn2+ introduced chelation enhanced fluorescence that was unaltered even addition of other metal ion. The formation of excited state complexation of FBNPs-Zn2+ was supported by UV–vis absorption titration, fluorescence lifetime and zeta particle size of FBNPs with and without addition of Zn2+. The mode of binding and interaction was confirmed by results procured through NMR and IR spectroscopy. The stoichiometry and binding constant estimated by Job’s plot and Benesi-Hildebrand plot. The limit of detection (LOD) for Zn2+ was 0.0011 μg/mL. The fascinating feature of present nano probe (FBNPs) is that outstanding intracellular Zn2+ sensor in MDA-MB-231 living cells with nominal toxicity. The exceptional photo physical and biocompatible nature of FBNPs signifying on site application of prepared fluorescent organic nanoparticles in environmental as well as biomedical field." @default.
- W2795751330 created "2018-04-13" @default.
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- W2795751330 date "2018-08-01" @default.
- W2795751330 modified "2023-10-16" @default.
- W2795751330 title "Intracellular imaging of zinc ion in living cells by fluorescein based organic nanoparticles" @default.
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- W2795751330 doi "https://doi.org/10.1016/j.snb.2018.03.186" @default.
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