FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2795806962> ?p ?o ?g. }

• W2795806962 abstract "Animal models for examining human breast cancer (HBC) carcinogenesis have been extensively studied and proposed. With the recent advent of immunotherapy, significant attention has been focused on the dog as a model for human cancer. Dogs develop mammary tumors and other cancer types spontaneously with an intact immune system, which exhibit a number of clinical and molecular similarities to HBC. In addition to the spontaneous tumor presentation, the clinical similarities between human and canine mammary tumors (CMT) include the age at onset, hormonal etiology and course of the diseases. Furthermore, factors that affect the disease outcome, including tumor size, stage and lymph node invasion, are similar in HBC and CMT. Similarly, the molecular characteristics of steroid receptor, epidermal growth factor, proliferation marker, metalloproteinase and cyclooxygenase expression, and the mutation of the p53 tumor suppressor gene in CMT, mimic HBC. Furthermore, ductal carcinomas in situ in human and canine mammary glands are particularly similar in their pathological, molecular and visual characteristics. These CMT characteristics and their similarities to HBC indicate that the dog could be an excellent model for the study of human disease. These similarities are discussed in detail in the present review, and are compared with the in vitro and other in vivo animal models available." @default.
• W2795806962 created "2018-04-13" @default.
• W2795806962 creator A5033197110 @default.
• W2795806962 creator A5082087352 @default.
• W2795806962 date "2018-04-02" @default.
• W2795806962 modified "2023-10-09" @default.
• W2795806962 title "Canine mammary tumors as a model for human disease (Review)" @default.
• W2795806962 cites W127043432 @default.
• W2795806962 cites W138450364 @default.
• W2795806962 cites W1422339448 @default.
• W2795806962 cites W1483285971 @default.
• W2795806962 cites W1493303652 @default.
• W2795806962 cites W1504534505 @default.
• W2795806962 cites W150807911 @default.
• W2795806962 cites W1547728820 @default.
• W2795806962 cites W1559451312 @default.
• W2795806962 cites W1564857146 @default.
• W2795806962 cites W1586032508 @default.
• W2795806962 cites W1664755364 @default.
• W2795806962 cites W1782413320 @default.
• W2795806962 cites W1845888499 @default.
• W2795806962 cites W1852168616 @default.
• W2795806962 cites W1883992304 @default.
• W2795806962 cites W1886493391 @default.
• W2795806962 cites W1898676131 @default.
• W2795806962 cites W1926267001 @default.
• W2795806962 cites W1964255717 @default.
• W2795806962 cites W1964769852 @default.
• W2795806962 cites W1965865401 @default.
• W2795806962 cites W1966542709 @default.
• W2795806962 cites W1966561908 @default.
• W2795806962 cites W1968482709 @default.
• W2795806962 cites W1968610929 @default.
• W2795806962 cites W1969600377 @default.
• W2795806962 cites W1971439306 @default.
• W2795806962 cites W1973669584 @default.
• W2795806962 cites W1976228409 @default.
• W2795806962 cites W1977089996 @default.
• W2795806962 cites W1983274306 @default.
• W2795806962 cites W1983311486 @default.
• W2795806962 cites W1984431867 @default.
• W2795806962 cites W1989663680 @default.
• W2795806962 cites W1991527725 @default.
• W2795806962 cites W1993326038 @default.
• W2795806962 cites W1998369376 @default.
• W2795806962 cites W1999350303 @default.
• W2795806962 cites W1999435920 @default.
• W2795806962 cites W2000413123 @default.
• W2795806962 cites W2002315461 @default.
• W2795806962 cites W2002840892 @default.
• W2795806962 cites W2003336662 @default.
• W2795806962 cites W2003366192 @default.
• W2795806962 cites W2003685376 @default.
• W2795806962 cites W2012213678 @default.
• W2795806962 cites W2014901738 @default.
• W2795806962 cites W2015187541 @default.
• W2795806962 cites W2015848291 @default.
• W2795806962 cites W2018208300 @default.
• W2795806962 cites W2019739286 @default.
• W2795806962 cites W2020459118 @default.
• W2795806962 cites W2022989929 @default.
• W2795806962 cites W2025472821 @default.
• W2795806962 cites W2029895840 @default.
• W2795806962 cites W2030932194 @default.
• W2795806962 cites W2031205003 @default.
• W2795806962 cites W2035409717 @default.
• W2795806962 cites W2037054135 @default.
• W2795806962 cites W2038435107 @default.
• W2795806962 cites W2038964127 @default.
• W2795806962 cites W2039407842 @default.
• W2795806962 cites W2039653469 @default.
• W2795806962 cites W2041247730 @default.
• W2795806962 cites W2042387032 @default.
• W2795806962 cites W2044051237 @default.
• W2795806962 cites W2047209914 @default.
• W2795806962 cites W2052184487 @default.
• W2795806962 cites W2053277232 @default.
• W2795806962 cites W2053905766 @default.
• W2795806962 cites W2055209420 @default.
• W2795806962 cites W2055235909 @default.
• W2795806962 cites W2057086710 @default.
• W2795806962 cites W2059354961 @default.
• W2795806962 cites W2062063276 @default.
• W2795806962 cites W2062271906 @default.
• W2795806962 cites W2065118454 @default.
• W2795806962 cites W2065646591 @default.
• W2795806962 cites W2066194961 @default.
• W2795806962 cites W2066221064 @default.
• W2795806962 cites W2073246896 @default.
• W2795806962 cites W2073255752 @default.
• W2795806962 cites W2073947685 @default.
• W2795806962 cites W2075733559 @default.
• W2795806962 cites W2078671364 @default.
• W2795806962 cites W2081797024 @default.
• W2795806962 cites W2084359613 @default.
• W2795806962 cites W2084446510 @default.
• W2795806962 cites W2086587390 @default.
• W2795806962 cites W2089094422 @default.
• W2795806962 cites W2089271887 @default.
• W2795806962 cites W2096663717 @default.

• next