Matches in SemOpenAlex for { <https://semopenalex.org/work/W2795919221> ?p ?o ?g. }
- W2795919221 endingPage "170" @default.
- W2795919221 startingPage "170" @default.
- W2795919221 abstract "Piscine orthoreovirus (PRV-1) causes heart and skeletal muscle inflammation (HSMI) in farmed Atlantic salmon (Salmo salar). Recently, a novel PRV (formerly PRV-Om, here called PRV-3), was found in rainbow trout (Oncorhynchus mykiss) with HSMI-like disease. PRV is considered to be an emerging pathogen in farmed salmonids. In this study, molecular and antigenic characterization of PRV-3 was performed. Erythrocytes are the main target cells for PRV, and blood samples that were collected from experimentally challenged fish were used as source of virus. Virus particles were purified by gradient ultracentrifugation and the complete coding sequences of PRV-3 were obtained by Illumina sequencing. When compared to PRV-1, the nucleotide identity of the coding regions was 80.1%, and the amino acid identities of the predicted PRV-3 proteins varied from 96.7% (λ1) to 79.1% (σ3). Phylogenetic analysis showed that PRV-3 belongs to a separate cluster. The region encoding σ3 were sequenced from PRV-3 isolates collected from rainbow trout in Europe. These sequences clustered together, but were distant from PRV-3 that was isolated from rainbow trout in Norway. Bioinformatic analyses of PRV-3 proteins revealed that predicted secondary structures and functional domains were conserved between PRV-3 and PRV-1. Rabbit antisera raised against purified virus or various recombinant virus proteins from PRV-1 all cross-reacted with PRV-3. Our findings indicate that despite different species preferences of the PRV subtypes, several genetic, antigenic, and structural properties are conserved between PRV-1 and-3." @default.
- W2795919221 created "2018-04-13" @default.
- W2795919221 creator A5024656049 @default.
- W2795919221 creator A5027340924 @default.
- W2795919221 creator A5029657943 @default.
- W2795919221 creator A5043187304 @default.
- W2795919221 creator A5043645280 @default.
- W2795919221 creator A5054377223 @default.
- W2795919221 creator A5057304546 @default.
- W2795919221 creator A5076385340 @default.
- W2795919221 creator A5085615393 @default.
- W2795919221 creator A5089033050 @default.
- W2795919221 date "2018-04-02" @default.
- W2795919221 modified "2023-10-18" @default.
- W2795919221 title "Molecular and Antigenic Characterization of Piscine orthoreovirus (PRV) from Rainbow Trout (Oncorhynchus mykiss)" @default.
- W2795919221 cites W1519266993 @default.
- W2795919221 cites W1928030931 @default.
- W2795919221 cites W1958095582 @default.
- W2795919221 cites W1978396569 @default.
- W2795919221 cites W1982836352 @default.
- W2795919221 cites W2000775429 @default.
- W2795919221 cites W2007841228 @default.
- W2795919221 cites W2022783296 @default.
- W2795919221 cites W2027448315 @default.
- W2795919221 cites W2028824635 @default.
- W2795919221 cites W2042559521 @default.
- W2795919221 cites W2044444467 @default.
- W2795919221 cites W2055792966 @default.
- W2795919221 cites W2065387557 @default.
- W2795919221 cites W2092199562 @default.
- W2795919221 cites W2096316084 @default.
- W2795919221 cites W2097369137 @default.
- W2795919221 cites W2097856292 @default.
- W2795919221 cites W2104715364 @default.
- W2795919221 cites W2117756276 @default.
- W2795919221 cites W2120902911 @default.
- W2795919221 cites W2134082339 @default.
- W2795919221 cites W2141052558 @default.
- W2795919221 cites W2142999835 @default.
- W2795919221 cites W2147290902 @default.
- W2795919221 cites W2152207030 @default.
- W2795919221 cites W2153187042 @default.
- W2795919221 cites W2153880874 @default.
- W2795919221 cites W2163377027 @default.
- W2795919221 cites W2166504915 @default.
- W2795919221 cites W2167171684 @default.
- W2795919221 cites W2225589459 @default.
- W2795919221 cites W2232595415 @default.
- W2795919221 cites W2293633200 @default.
- W2795919221 cites W2311203695 @default.
- W2795919221 cites W2337858621 @default.
- W2795919221 cites W2438042720 @default.
- W2795919221 cites W2486362673 @default.
- W2795919221 cites W2535704018 @default.
- W2795919221 cites W2542246033 @default.
- W2795919221 cites W2589730151 @default.
- W2795919221 cites W2598770484 @default.
- W2795919221 cites W2726185788 @default.
- W2795919221 cites W2745631600 @default.
- W2795919221 cites W2781679092 @default.
- W2795919221 cites W3173832084 @default.
- W2795919221 doi "https://doi.org/10.3390/v10040170" @default.
- W2795919221 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5923464" @default.
- W2795919221 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29614838" @default.
- W2795919221 hasPublicationYear "2018" @default.
- W2795919221 type Work @default.
- W2795919221 sameAs 2795919221 @default.
- W2795919221 citedByCount "35" @default.
- W2795919221 countsByYear W27959192212018 @default.
- W2795919221 countsByYear W27959192212019 @default.
- W2795919221 countsByYear W27959192212020 @default.
- W2795919221 countsByYear W27959192212021 @default.
- W2795919221 countsByYear W27959192212022 @default.
- W2795919221 countsByYear W27959192212023 @default.
- W2795919221 crossrefType "journal-article" @default.
- W2795919221 hasAuthorship W2795919221A5024656049 @default.
- W2795919221 hasAuthorship W2795919221A5027340924 @default.
- W2795919221 hasAuthorship W2795919221A5029657943 @default.
- W2795919221 hasAuthorship W2795919221A5043187304 @default.
- W2795919221 hasAuthorship W2795919221A5043645280 @default.
- W2795919221 hasAuthorship W2795919221A5054377223 @default.
- W2795919221 hasAuthorship W2795919221A5057304546 @default.
- W2795919221 hasAuthorship W2795919221A5076385340 @default.
- W2795919221 hasAuthorship W2795919221A5085615393 @default.
- W2795919221 hasAuthorship W2795919221A5089033050 @default.
- W2795919221 hasBestOaLocation W27959192211 @default.
- W2795919221 hasConcept C104317684 @default.
- W2795919221 hasConcept C147483822 @default.
- W2795919221 hasConcept C159047783 @default.
- W2795919221 hasConcept C193252679 @default.
- W2795919221 hasConcept C2522874641 @default.
- W2795919221 hasConcept C2777940460 @default.
- W2795919221 hasConcept C2909208804 @default.
- W2795919221 hasConcept C2994167347 @default.
- W2795919221 hasConcept C505870484 @default.
- W2795919221 hasConcept C54355233 @default.
- W2795919221 hasConcept C86803240 @default.
- W2795919221 hasConceptScore W2795919221C104317684 @default.