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- W2795992368 abstract "Abstract The present review summarises the current knowledge of the biology, biochemistry and molecular aspects of S. aurantiacum in context with the broader knowledge on Scedosporium spp, generated over the past decade. Recently, the genus has undergone two taxonomical reviews. S. aurantiacum is widely distributed in all ecological niches and geographical locations. It is a highly pathogenic opportunist capable of causing a broad range of diseases via infections occurring in the lungs, sinuses, eyes, bones, central nervous system and internal organs. While S. aurantiacum has a minor role in the colonisation of lungs in Germany and France, in Australia, it comprises approximately one-third of Scedosporium spp. recovered from cystic fibrosis lungs where it may co-exist with other prokaryotic lung inhabitants such as Pseudomonas aeruginosa. However, very little is known about mixed bacterial–fungal interactions or host–fungal interactions in the lungs, all of which may have an impact on disease outcome. Also, the nature of potential virulence factors such as production of particular proteases would require more research. A wide range of molecular diagnostic techniques now available can facilitate rapid and accurate identification of Scedosporium spp. in clinical specimens and environmental samples. However, molecular tools allowing gene overexpression and knockout studies are yet to be fully developed. A draft genome is currently available for S. aurantiacum strain WM 09.24 (CBS136047), an Australian environmental isolate. The emerging genomic tools and metabolic and transcriptomic studies discussed will further advance understanding of the pathogenic mechanisms of members of the genus Scedosporium, including S. aurantiacum." @default.
- W2795992368 created "2018-04-13" @default.
- W2795992368 creator A5005296981 @default.
- W2795992368 creator A5011754890 @default.
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- W2795992368 creator A5044873766 @default.
- W2795992368 creator A5077820178 @default.
- W2795992368 creator A5086363018 @default.
- W2795992368 date "2018-06-01" @default.
- W2795992368 modified "2023-10-16" @default.
- W2795992368 title "Biological, biochemical and molecular aspects of Scedosporium aurantiacum, a primary and opportunistic fungal pathogen" @default.
- W2795992368 cites W1562117121 @default.
- W2795992368 cites W1599002996 @default.
- W2795992368 cites W1609495085 @default.
- W2795992368 cites W1654280973 @default.
- W2795992368 cites W1744228079 @default.
- W2795992368 cites W1824079566 @default.
- W2795992368 cites W1932312459 @default.
- W2795992368 cites W1984852783 @default.
- W2795992368 cites W1985371834 @default.
- W2795992368 cites W1987221920 @default.
- W2795992368 cites W1990652136 @default.
- W2795992368 cites W1998808728 @default.
- W2795992368 cites W2000549577 @default.
- W2795992368 cites W2003840051 @default.
- W2795992368 cites W2012508946 @default.
- W2795992368 cites W2015734692 @default.
- W2795992368 cites W2017985218 @default.
- W2795992368 cites W2023046336 @default.
- W2795992368 cites W2025388427 @default.
- W2795992368 cites W2027469339 @default.
- W2795992368 cites W2033695145 @default.
- W2795992368 cites W2038267036 @default.
- W2795992368 cites W2038485278 @default.
- W2795992368 cites W2042823694 @default.
- W2795992368 cites W2043888312 @default.
- W2795992368 cites W2053708683 @default.
- W2795992368 cites W2058571383 @default.
- W2795992368 cites W2062831182 @default.
- W2795992368 cites W2063988751 @default.
- W2795992368 cites W2074614011 @default.
- W2795992368 cites W2078314973 @default.
- W2795992368 cites W2083366630 @default.
- W2795992368 cites W2089726284 @default.
- W2795992368 cites W2094740808 @default.
- W2795992368 cites W2095254076 @default.
- W2795992368 cites W2102406508 @default.
- W2795992368 cites W2102650257 @default.
- W2795992368 cites W2102915977 @default.
- W2795992368 cites W2103618562 @default.
- W2795992368 cites W2104849034 @default.
- W2795992368 cites W2106014948 @default.
- W2795992368 cites W2110439135 @default.
- W2795992368 cites W2114501775 @default.
- W2795992368 cites W2119217043 @default.
- W2795992368 cites W2119871660 @default.
- W2795992368 cites W2120569572 @default.
- W2795992368 cites W2120924657 @default.
- W2795992368 cites W2120981631 @default.
- W2795992368 cites W2123618159 @default.
- W2795992368 cites W2129373752 @default.
- W2795992368 cites W2129408965 @default.
- W2795992368 cites W2129822772 @default.
- W2795992368 cites W2129870632 @default.
- W2795992368 cites W2132040510 @default.
- W2795992368 cites W2134586696 @default.
- W2795992368 cites W2136334655 @default.
- W2795992368 cites W2137473653 @default.
- W2795992368 cites W2140507337 @default.
- W2795992368 cites W2146491286 @default.
- W2795992368 cites W2149531397 @default.
- W2795992368 cites W2153584505 @default.
- W2795992368 cites W2158059832 @default.
- W2795992368 cites W2158464667 @default.
- W2795992368 cites W2159367637 @default.
- W2795992368 cites W2161633414 @default.
- W2795992368 cites W2161965506 @default.
- W2795992368 cites W2164458652 @default.
- W2795992368 cites W2169717562 @default.
- W2795992368 cites W2206384134 @default.
- W2795992368 cites W2281092694 @default.
- W2795992368 cites W2290972095 @default.
- W2795992368 cites W2325565338 @default.
- W2795992368 cites W2335056811 @default.
- W2795992368 cites W2418549414 @default.
- W2795992368 cites W2470231000 @default.
- W2795992368 cites W2573646179 @default.
- W2795992368 cites W2587912756 @default.
- W2795992368 cites W2615586271 @default.
- W2795992368 cites W2621480641 @default.
- W2795992368 cites W2753939864 @default.
- W2795992368 cites W2755421067 @default.
- W2795992368 cites W2761544392 @default.
- W2795992368 cites W2773389757 @default.
- W2795992368 cites W2792930549 @default.
- W2795992368 cites W2916792389 @default.
- W2795992368 doi "https://doi.org/10.1016/j.fbr.2018.03.001" @default.