Matches in SemOpenAlex for { <https://semopenalex.org/work/W2796117629> ?p ?o ?g. }
- W2796117629 endingPage "351" @default.
- W2796117629 startingPage "343" @default.
- W2796117629 abstract "Genomic imprinting is the process of epigenetic modification whereby genes are expressed in a parent-of-origin dependent manner; it plays an important role in normal growth and development. Parthenogenetic embryos contain only the maternal genome. Parthenogenetic embryonic stem cells could be useful for studying imprinted genes. In humans, mature cystic ovarian teratomas originate from parthenogenetic activation of oocytes; they are composed of highly differentiated mature tissues containing all three germ layers. To establish human parthenogenetic induced pluripotent stem cell lines (PgHiPSCs), we generated parthenogenetic fibroblasts from ovarian teratoma tissues. We compared global DNA methylation status of PgHiPSCs with that of biparental human induced pluripotent stem cells by using Illumina Infinium HumanMethylation450 BeadChip array. This analysis identified novel single imprinted CpG sites. We further tested DNA methylation patterns of two of these sites using bisulfite sequencing and described novel candidate imprinted CpG sites. These results confirm that PgHiPSCs are a powerful tool for identifying imprinted genes and investigating their roles in human development and diseases." @default.
- W2796117629 created "2018-04-13" @default.
- W2796117629 creator A5016621874 @default.
- W2796117629 creator A5019630278 @default.
- W2796117629 creator A5025944277 @default.
- W2796117629 creator A5030283787 @default.
- W2796117629 creator A5037834486 @default.
- W2796117629 creator A5055877596 @default.
- W2796117629 creator A5060137218 @default.
- W2796117629 creator A5065645577 @default.
- W2796117629 creator A5067831607 @default.
- W2796117629 creator A5070691621 @default.
- W2796117629 creator A5075796763 @default.
- W2796117629 creator A5083528932 @default.
- W2796117629 creator A5091843504 @default.
- W2796117629 date "2018-04-03" @default.
- W2796117629 modified "2023-10-12" @default.
- W2796117629 title "Novel imprinted single CpG sites found by global DNA methylation analysis in human parthenogenetic induced pluripotent stem cells" @default.
- W2796117629 cites W1829128263 @default.
- W2796117629 cites W1869773196 @default.
- W2796117629 cites W1964060034 @default.
- W2796117629 cites W1966504370 @default.
- W2796117629 cites W1966981147 @default.
- W2796117629 cites W1976274498 @default.
- W2796117629 cites W1985542606 @default.
- W2796117629 cites W1991264207 @default.
- W2796117629 cites W1996499787 @default.
- W2796117629 cites W2006856796 @default.
- W2796117629 cites W2013346353 @default.
- W2796117629 cites W2014489902 @default.
- W2796117629 cites W2017502278 @default.
- W2796117629 cites W2023707980 @default.
- W2796117629 cites W2023847394 @default.
- W2796117629 cites W2031023917 @default.
- W2796117629 cites W2033728888 @default.
- W2796117629 cites W2036764668 @default.
- W2796117629 cites W2037818631 @default.
- W2796117629 cites W2046141276 @default.
- W2796117629 cites W2069477672 @default.
- W2796117629 cites W2077981163 @default.
- W2796117629 cites W2085791754 @default.
- W2796117629 cites W2091601353 @default.
- W2796117629 cites W2097126190 @default.
- W2796117629 cites W2102868331 @default.
- W2796117629 cites W2103211527 @default.
- W2796117629 cites W2108740302 @default.
- W2796117629 cites W2109831376 @default.
- W2796117629 cites W2111589765 @default.
- W2796117629 cites W2114728169 @default.
- W2796117629 cites W2127540087 @default.
- W2796117629 cites W2131892345 @default.
- W2796117629 cites W2132480780 @default.
- W2796117629 cites W2136810541 @default.
- W2796117629 cites W2141298577 @default.
- W2796117629 cites W2144533164 @default.
- W2796117629 cites W2154032366 @default.
- W2796117629 cites W2157805276 @default.
- W2796117629 cites W2161229967 @default.
- W2796117629 cites W2165047318 @default.
- W2796117629 cites W2170902102 @default.
- W2796117629 cites W2171538603 @default.
- W2796117629 cites W2184561450 @default.
- W2796117629 cites W2294589073 @default.
- W2796117629 cites W2329888282 @default.
- W2796117629 doi "https://doi.org/10.1080/15592294.2018.1460033" @default.
- W2796117629 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6140819" @default.
- W2796117629 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29613829" @default.
- W2796117629 hasPublicationYear "2018" @default.
- W2796117629 type Work @default.
- W2796117629 sameAs 2796117629 @default.
- W2796117629 citedByCount "7" @default.
- W2796117629 countsByYear W27961176292018 @default.
- W2796117629 countsByYear W27961176292019 @default.
- W2796117629 countsByYear W27961176292020 @default.
- W2796117629 countsByYear W27961176292022 @default.
- W2796117629 crossrefType "journal-article" @default.
- W2796117629 hasAuthorship W2796117629A5016621874 @default.
- W2796117629 hasAuthorship W2796117629A5019630278 @default.
- W2796117629 hasAuthorship W2796117629A5025944277 @default.
- W2796117629 hasAuthorship W2796117629A5030283787 @default.
- W2796117629 hasAuthorship W2796117629A5037834486 @default.
- W2796117629 hasAuthorship W2796117629A5055877596 @default.
- W2796117629 hasAuthorship W2796117629A5060137218 @default.
- W2796117629 hasAuthorship W2796117629A5065645577 @default.
- W2796117629 hasAuthorship W2796117629A5067831607 @default.
- W2796117629 hasAuthorship W2796117629A5070691621 @default.
- W2796117629 hasAuthorship W2796117629A5075796763 @default.
- W2796117629 hasAuthorship W2796117629A5083528932 @default.
- W2796117629 hasAuthorship W2796117629A5091843504 @default.
- W2796117629 hasBestOaLocation W27961176291 @default.
- W2796117629 hasConcept C103725303 @default.
- W2796117629 hasConcept C104317684 @default.
- W2796117629 hasConcept C107459253 @default.
- W2796117629 hasConcept C140173407 @default.
- W2796117629 hasConcept C145103041 @default.
- W2796117629 hasConcept C150194340 @default.
- W2796117629 hasConcept C190727270 @default.
- W2796117629 hasConcept C196843134 @default.