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- W2796372967 abstract "You have accessJournal of UrologyProstate Cancer: Detection & Screening III1 Apr 2018MP40-09 MOVING TOWARDS ZERO SEPSIS; OUR REGISTRARS CAN DO IT! AN ANALYSIS OF 214 CASES OF TRANSPERINEAL PROSTATE BIOPSY OVER THREE YEARS Hansi Pathirana, Jonathan Kam, Yuigi Yuminaga, Kieran Beattie, Sunny Nalavenkata, Mohan Arianayagam, Bertram Canagasingham, Richard Ferguson, Raymond Ko, Celi Varol, Matthew Winter, and Mohamed Khadra Hansi PathiranaHansi Pathirana More articles by this author , Jonathan KamJonathan Kam More articles by this author , Yuigi YuminagaYuigi Yuminaga More articles by this author , Kieran BeattieKieran Beattie More articles by this author , Sunny NalavenkataSunny Nalavenkata More articles by this author , Mohan ArianayagamMohan Arianayagam More articles by this author , Bertram CanagasinghamBertram Canagasingham More articles by this author , Richard FergusonRichard Ferguson More articles by this author , Raymond KoRaymond Ko More articles by this author , Celi VarolCeli Varol More articles by this author , Matthew WinterMatthew Winter More articles by this author , and Mohamed KhadraMohamed Khadra More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2018.02.1276AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Transperineal (TP) biopsy is an increasingly utilised method of prostate biopsy which is associated with low rates of sepsis. This is particularly important with the rise of multi-resistant organisms which make sepsis from standard trans-rectal prostate biopsy more difficult to prevent and manage. This study aimed to assess post-operative complications of TP prostate biopsy performed by Urological Trainees at an Australian teaching centre. METHODS Institutional review board approval for this project was granted (HREC File No, 17-27(A)) by the Nepean Blue Mountains Local Health District Human Research Ethics Committee.Males who underwent TP biopsy from April 2015 until May 2017 at Nepean Hospital, Kingswood, Australia were included in the study. TP biopsy was performed with a standard template grid approach, with additional biopsies taken of any suspicious lesions identified on multi-parametric MRI. Cases received a pre-operative single dose of intravenous cephazolin as prophylaxis. All cases were followed up for re-presentation to hospital within 30 days of biopsy. The primary outcome was re-presentation for TP biopsy related complications. Data was analysed using SPSS 24.0. RESULTS A total of 214 males were included with a mean age of 63.4, PSA 9.4ng/mL and prostate volume of 54.3cc. Overall, twenty-one cases (9.8%) had hospital re-presentation within 30 days, with biopsy related complications. Thirteen cases (6%) re-presented with urinary retention and five cases (2.3%) experienced haematuria with clot retention. Five cases (2.3%) developed culture-proven urinary tract infections, with only one of these cases (0.4%) having an associated fever (but no haemodynamic instability). None of the culture-proven UTI cases had positive blood cultures or required intensive care unit admission. CONCLUSIONS Our study supports the growing literature supporting the use of TP biopsy in reducing the rate of urosepsis following prostate biopsy. With rising rates of multi-drug resistance in normal rectal flora, this is becoming highly relevant in the arena of prostate biopsy for cancer diagnosis and active surveillance. At our centre, TP biopsy has resulted in a 0.4% sepsis rate after 3 years, and an acceptable hospital representation rate, for acute urinary retention and clot retention. © 2018FiguresReferencesRelatedDetails Volume 199Issue 4SApril 2018Page: e523 Advertisement Copyright & Permissions© 2018MetricsAuthor Information Hansi Pathirana More articles by this author Jonathan Kam More articles by this author Yuigi Yuminaga More articles by this author Kieran Beattie More articles by this author Sunny Nalavenkata More articles by this author Mohan Arianayagam More articles by this author Bertram Canagasingham More articles by this author Richard Ferguson More articles by this author Raymond Ko More articles by this author Celi Varol More articles by this author Matthew Winter More articles by this author Mohamed Khadra More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ..." @default.
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- W2796372967 title "MP40-09 MOVING TOWARDS ZERO SEPSIS; OUR REGISTRARS CAN DO IT! AN ANALYSIS OF 214 CASES OF TRANSPERINEAL PROSTATE BIOPSY OVER THREE YEARS" @default.
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