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- W2796396144 abstract "Clinical data of 65 histologically documented ulcerative colitis patients from January 2001 to December 2013 were prospectively recorded till June 2017 and analysed to determine the outcome of long-term maintenance treatment. Drugs used were 5-aminosalicylates, steroids and azathioprine. Primary outcome measure was relapse. Though 73.8% patients relapsed, most occurred within the first five years with mild to moderate severity and were easily controlled with the same medicines. None had progressive disease; drug discontinuation was possible in six cases. Side effects of drugs were negligible. Rates of surgery, colon cancer, complications and disease-related death were very low. Longer disease duration, azathioprine discontinuation and 5-aminosalicylate use in dose < 2.4 g/d were positively associated with relapses. Biologics were not used in any patient. We conclude that long-term effective use of low-cost drugs in India may obviate the need for newer more expensive drugs." @default.
- W2796396144 created "2018-04-13" @default.
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- W2796396144 date "2018-04-04" @default.
- W2796396144 modified "2023-09-25" @default.
- W2796396144 title "Long-term maintenance treatment of ulcerative colitis in eastern India: a 15-year follow-up" @default.
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- W2796396144 doi "https://doi.org/10.1177/0049475518765291" @default.
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