Matches in SemOpenAlex for { <https://semopenalex.org/work/W2796402949> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2796402949 abstract "To explore the clinical features and outcomes of relapsed childhood acute lymphoblastic leukemia (ALL) at our center, achieve the early detection of risk factors for recurrence and assess the risk-stratified Guangdong (GD)-2008 ALL protocol.In total, 59 Chinese childhood ALL patients treated with the GD-2008 ALL protocol who relapsed between July 2008 and March 2015 were enrolled in this study. Their clinical features and outcomes were retrospectively analyzed and compared with those of 218 patients who achieved continuous complete remission.Of the 285 study participants, 8 died of treatment-related infections or other complications before remission, 218 achieved continuous complete remission, and 59 patients relapsed, yielding a relapse rate of 20.7%. The number of relapsed patients in the standard-risk, intermediate-risk, and high-risk groups were 15 (17.0%), 27 (19.7%), and 17 (32.7%), respectively. Risk factors included age 10 years and above at first diagnosis, white blood cell (WBC) count ≥50×10/L, poor prednisone response, failure to achieve bone marrow complete remission at day 15 of induction chemotherapy. High-risk stratification and a high level (≥0.1%) of minimal residual disease at day 33 were the risk factors for relapse. Multivariate analysis showed that a high WBC at first diagnosis was an independent risk factor for relapse (P=0.000).For the GD-2008 ALL risk stratification based on age and initial WBC, 10 years of age and WBC 50×10/L can be used as cut-offs. Patients at high risk benefited from the GD-2008 ALL protocol. In addition, the impact of minimal residual disease on prognosis should be considered." @default.
- W2796402949 created "2018-04-13" @default.
- W2796402949 creator A5019563116 @default.
- W2796402949 creator A5034851476 @default.
- W2796402949 creator A5045330928 @default.
- W2796402949 creator A5045789487 @default.
- W2796402949 creator A5050616688 @default.
- W2796402949 creator A5052883326 @default.
- W2796402949 creator A5064842058 @default.
- W2796402949 creator A5066827467 @default.
- W2796402949 creator A5075400501 @default.
- W2796402949 date "2018-08-01" @default.
- W2796402949 modified "2023-09-25" @default.
- W2796402949 title "Reassessment of the Risk-stratified GD-2008 ALL Protocol" @default.
- W2796402949 cites W1487218686 @default.
- W2796402949 cites W1531166947 @default.
- W2796402949 cites W1919084303 @default.
- W2796402949 cites W1976767488 @default.
- W2796402949 cites W1984233718 @default.
- W2796402949 cites W1989485003 @default.
- W2796402949 cites W2009582466 @default.
- W2796402949 cites W2027093812 @default.
- W2796402949 cites W2049204537 @default.
- W2796402949 cites W2051646706 @default.
- W2796402949 cites W2063662864 @default.
- W2796402949 cites W2067607205 @default.
- W2796402949 cites W2089583676 @default.
- W2796402949 cites W2092925278 @default.
- W2796402949 cites W2094395262 @default.
- W2796402949 cites W2103975928 @default.
- W2796402949 cites W2127016956 @default.
- W2796402949 cites W2129291628 @default.
- W2796402949 cites W2148202982 @default.
- W2796402949 cites W2469996266 @default.
- W2796402949 cites W2508745168 @default.
- W2796402949 cites W2528140859 @default.
- W2796402949 cites W2528775064 @default.
- W2796402949 doi "https://doi.org/10.1097/mph.0000000000001131" @default.
- W2796402949 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29608548" @default.
- W2796402949 hasPublicationYear "2018" @default.
- W2796402949 type Work @default.
- W2796402949 sameAs 2796402949 @default.
- W2796402949 citedByCount "2" @default.
- W2796402949 countsByYear W27964029492020 @default.
- W2796402949 countsByYear W27964029492021 @default.
- W2796402949 crossrefType "journal-article" @default.
- W2796402949 hasAuthorship W2796402949A5019563116 @default.
- W2796402949 hasAuthorship W2796402949A5034851476 @default.
- W2796402949 hasAuthorship W2796402949A5045330928 @default.
- W2796402949 hasAuthorship W2796402949A5045789487 @default.
- W2796402949 hasAuthorship W2796402949A5050616688 @default.
- W2796402949 hasAuthorship W2796402949A5052883326 @default.
- W2796402949 hasAuthorship W2796402949A5064842058 @default.
- W2796402949 hasAuthorship W2796402949A5066827467 @default.
- W2796402949 hasAuthorship W2796402949A5075400501 @default.
- W2796402949 hasConcept C126322002 @default.
- W2796402949 hasConcept C187212893 @default.
- W2796402949 hasConcept C2778488018 @default.
- W2796402949 hasConcept C2778720950 @default.
- W2796402949 hasConcept C2779823535 @default.
- W2796402949 hasConcept C2780007613 @default.
- W2796402949 hasConcept C3020404979 @default.
- W2796402949 hasConcept C38180746 @default.
- W2796402949 hasConcept C50440223 @default.
- W2796402949 hasConcept C71924100 @default.
- W2796402949 hasConceptScore W2796402949C126322002 @default.
- W2796402949 hasConceptScore W2796402949C187212893 @default.
- W2796402949 hasConceptScore W2796402949C2778488018 @default.
- W2796402949 hasConceptScore W2796402949C2778720950 @default.
- W2796402949 hasConceptScore W2796402949C2779823535 @default.
- W2796402949 hasConceptScore W2796402949C2780007613 @default.
- W2796402949 hasConceptScore W2796402949C3020404979 @default.
- W2796402949 hasConceptScore W2796402949C38180746 @default.
- W2796402949 hasConceptScore W2796402949C50440223 @default.
- W2796402949 hasConceptScore W2796402949C71924100 @default.
- W2796402949 hasLocation W27964029491 @default.
- W2796402949 hasLocation W27964029492 @default.
- W2796402949 hasOpenAccess W2796402949 @default.
- W2796402949 hasPrimaryLocation W27964029491 @default.
- W2796402949 hasRelatedWork W1981672005 @default.
- W2796402949 hasRelatedWork W2017435982 @default.
- W2796402949 hasRelatedWork W2045911116 @default.
- W2796402949 hasRelatedWork W2080037698 @default.
- W2796402949 hasRelatedWork W2137726962 @default.
- W2796402949 hasRelatedWork W2375269632 @default.
- W2796402949 hasRelatedWork W2392185739 @default.
- W2796402949 hasRelatedWork W2394840621 @default.
- W2796402949 hasRelatedWork W2417044364 @default.
- W2796402949 hasRelatedWork W2790285106 @default.
- W2796402949 isParatext "false" @default.
- W2796402949 isRetracted "false" @default.
- W2796402949 magId "2796402949" @default.
- W2796402949 workType "article" @default.