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• W2796458158 abstract "Radiotherapy is one of the main therapeutic methods for cancers, but radiation resistance of cancer cells still remains a serious concern. Searching for radiosensitizers to overcome such resistance is therefore urgently required. The goal of this study is to evaluate and compare the radiosensitizing efficacy of Fe3O4-OA, Ag and Fe3O4@Ag nanoparticles on U251 cells. The results show that Fe3O4@Ag nanoparticles have the highest ability of radiosensitization among the three nanoparticles. The underlying mechanism of Fe3O4@Ag nanoparticles' radiosensitivity enhancement is through decrease of the cytoprotective autophagy at the early stage, and increase of the calcium-dependent apoptosis at the later stage. These findings suggest the potential application of Fe3O4@Ag nanoparticles as a highly effective nano-radiosensitizer for the treatment of glioblastoma cells." @default.
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• W2796458158 date "2018-04-03" @default.
• W2796458158 modified "2023-10-14" @default.
• W2796458158 title "Radiosensitivity enhancement of Fe₃O₄@Ag nanoparticles on human glioblastoma cells" @default.
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• W2796458158 doi "https://doi.org/10.1080/21691401.2018.1439843" @default.
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