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- W2796565963 abstract "Abstract This study presents a new approach for an electrochemical immunoassay using gold nanoparticle (AuNP)‐labeled antibodies and pre‐oxidation and reduction processes, followed by open circuit potential (OCP) measurement. Detection of the pregnancy marker, human chorionic gonadotropin hormone (hCG), was used as a model. After preparation of a sandwich‐type immunosystem, the pre‐oxidation and reduction processes were applied, followed by OCP detection. The applied potential and time period were studied for the optimization of pre‐oxidation and reduction processes. We observed that the pre‐oxidation potential of 1.2 V for 60 s and reduction potential of −0.2 V for 30 s provided the highest OCP signal. The detection limit was 79 pg/mL using the optimal conditions. This system could be applied to a simplified and miniaturized diagnostic system for integration in compact analytical devices." @default.
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- W2796565963 date "2018-04-14" @default.
- W2796565963 modified "2023-09-26" @default.
- W2796565963 title "Gold Nanoparticle-labeled Electrochemical Immunoassay Using Open Circuit Potential for Human Chorionic Gonadotropin Detection" @default.
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- W2796565963 doi "https://doi.org/10.1002/elan.201700797" @default.
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