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• W2796730208 abstract "To estimate the incidence of all-cause outpatient community-acquired pneumonia (CAP) in adults in France from a national prospective observational study of CAP management in general practice (CAPA). Patients aged over 18 years presenting with signs or symptoms indicative of CAP associated with recent onset of unilateral crackles on auscultation and/or a new opacity on chest X-ray were included in the CAPA study. An ancillary survey (AIMSIS) aiming at identifying family physicians’ difficulties in including patients and at collecting their opinion on the use of an electronic case report form, determined the number of non-included eligible patients. A three-step analysis was then performed, including computation of the total number of eligible patients, adjustment for seasonality, and extrapolation to the French FP population using indirect standardization to adjust for differences in characteristics between CAPA FPs and French FPs. Between September 2011 and July 2012, 267 (63%) CAPA investigators included 886 CAP patients. Most patients presented with mild CAP. The rates of hospitalization and one-month case fatality were 7% and 0.3%, respectively. Data from 336 (79%) AIMSIS investigators identified 641 additional patients and estimated at 234,023 the number of CAP patients per year (incidence of 4.7 per 1000 persons per year). Using a pragmatic case definition of CAP patients, this study estimated an incidence of 4.7 per 1000 persons per year that is in the lower half of the range of estimated incidences reported in primary care settings in industrialized countries. Estimer l’incidence des pneumonies aiguës communautaires (PAC) chez les adultes pris en charge en médecine générale en France à partir des données prospectives observationnelles de l’étude CAPA. Ont été inclus dans l’étude CAPA, tous les patients de plus de 18 ans avec symptômes ou signes suggestifs de PAC, associés à un foyer unilatéral de râles crépitants et/ou une opacité radiologique récente. Une étude ancillaire sur l’avis des investigateurs à propos des inclusions et de la saisie informatique (AIMSIS) a déterminé le nombre de cas éligibles non-inclus. Une analyse en trois temps a été réalisée : calcul du nombre total de patients éligibles, ajustement selon la saisonnalité puis extrapolation à la population générale en ajustant sur les différences de caractéristiques entre les investigateurs de CAPA et les médecins généralistes français. De septembre 2011 à juillet 2012, 267 (63 %) investigateurs de CAPA ont inclus 886 patients, la plupart ayant une forme peu grave de PAC. Les taux d’hospitalisation et la létalité à un mois étaient respectivement de 7 % et de 0,3 %. Les données issues des 336 (79 %) investigateurs d’AIMSIS ont identifié 641 cas éligibles non-inclus et estimé à 234 023 le nombre total annuel de PAC (incidence de 4,7 pour 1000 adultes par an). Avec une définition pragmatique de PAC, cette étude montre une incidence annuelle de 4,7 pour 1000 adultes, qui se situe dans la moitié inférieure de l’intervalle des incidences des pays industrialisés." @default.
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• W2796730208 date "2018-09-01" @default.
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• W2796730208 title "Incidence of all-cause adult community-acquired pneumonia in primary care settings in France" @default.
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• W2796730208 doi "https://doi.org/10.1016/j.medmal.2018.02.012" @default.
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