Matches in SemOpenAlex for { <https://semopenalex.org/work/W2796793162> ?p ?o ?g. }
- W2796793162 abstract "Coptidis rhizoma (CR) is the dried rhizome of Coptis chinensis Franch., C. deltoidea C. Y. Cheng et Hsiao or C. teeta Wall. (Ranunculaceae) and is commonly used in Traditional Chinese Medicine for the treatment of various diseases including bacillary dysentery, typhoid, tuberculosis, epidemic cerebrospinal meningitis, empyrosis, pertussis, and other illnesses.A literature survey was conducted via SciFinder, ScieneDirect, PubMed, Springer, and Wiley databases. A total of 139 selected references were classified on the basis of their research scopes, including chemical investigation, quality evaluation and pharmacological studies.Many types of secondary metabolites including alkaloids, lignans, phenylpropanoids, flavonoids, phenolic compounds, saccharides, and steroids have been isolated from CR. Among them, protoberberine-type alkaloids, such as berberine, palmatine, coptisine, epiberberine, jatrorrhizine, columamine, are the main components of CR. Quantitative determination of these alkaloids is a very important aspect in the quality evaluation of CR. In recent years, with the advances in isolation and detection technologies, many new instruments and methods have been developed for the quantitative and qualitative analysis of the main alkaloids from CR. The quality control of CR has provided safety for pharmacological applications. These quality evaluation methods are also frequently employed to screen the active components from CR. Various investigations have shown that CR and its main alkaloids exhibited many powerful pharmacological effects including anti-inflammatory, anti-cancer, anti-diabetic, neuroprotective, cardioprotective, hypoglycemic, anti-Alzheimer and hepatoprotective activities.This review summarizes the recent phytochemical investigations, quality evaluation methods, the biological studies focusing on CR as well as its main alkaloids." @default.
- W2796793162 created "2018-04-24" @default.
- W2796793162 creator A5019062169 @default.
- W2796793162 creator A5027416136 @default.
- W2796793162 creator A5029673525 @default.
- W2796793162 creator A5058334717 @default.
- W2796793162 creator A5082516218 @default.
- W2796793162 creator A5088143812 @default.
- W2796793162 date "2018-03-07" @default.
- W2796793162 modified "2023-10-17" @default.
- W2796793162 title "Coptidis rhizoma and its main bioactive components: recent advances in chemical investigation, quality evaluation and pharmacological activity" @default.
- W2796793162 cites W1548418968 @default.
- W2796793162 cites W1587110588 @default.
- W2796793162 cites W1952615320 @default.
- W2796793162 cites W1962034018 @default.
- W2796793162 cites W1964136996 @default.
- W2796793162 cites W1965108118 @default.
- W2796793162 cites W1965216645 @default.
- W2796793162 cites W1966061516 @default.
- W2796793162 cites W1966832357 @default.
- W2796793162 cites W1968832330 @default.
- W2796793162 cites W1969382003 @default.
- W2796793162 cites W1969985837 @default.
- W2796793162 cites W1970439753 @default.
- W2796793162 cites W1972572472 @default.
- W2796793162 cites W1976833660 @default.
- W2796793162 cites W1980984607 @default.
- W2796793162 cites W1981395870 @default.
- W2796793162 cites W1987208314 @default.
- W2796793162 cites W1987856583 @default.
- W2796793162 cites W1989346488 @default.
- W2796793162 cites W1992506941 @default.
- W2796793162 cites W1996033782 @default.
- W2796793162 cites W1996826073 @default.
- W2796793162 cites W1997236186 @default.
- W2796793162 cites W1998263932 @default.
- W2796793162 cites W1998607508 @default.
- W2796793162 cites W1998850331 @default.
- W2796793162 cites W1999984504 @default.
- W2796793162 cites W2000193148 @default.
- W2796793162 cites W2000520368 @default.
- W2796793162 cites W2000766440 @default.
- W2796793162 cites W2003478263 @default.
- W2796793162 cites W2004922828 @default.
- W2796793162 cites W2005103744 @default.
- W2796793162 cites W2005188727 @default.
- W2796793162 cites W2005842922 @default.
- W2796793162 cites W2006684063 @default.
- W2796793162 cites W2011654869 @default.
- W2796793162 cites W2012378397 @default.
- W2796793162 cites W2013004937 @default.
- W2796793162 cites W2013713509 @default.
- W2796793162 cites W2017216492 @default.
- W2796793162 cites W2017654405 @default.
- W2796793162 cites W2022135121 @default.
- W2796793162 cites W2023117558 @default.
- W2796793162 cites W2024162840 @default.
- W2796793162 cites W2024509753 @default.
- W2796793162 cites W2027560638 @default.
- W2796793162 cites W2027683220 @default.
- W2796793162 cites W2029310119 @default.
- W2796793162 cites W2034137976 @default.
- W2796793162 cites W2043493115 @default.
- W2796793162 cites W2045083935 @default.
- W2796793162 cites W2045597244 @default.
- W2796793162 cites W2045999552 @default.
- W2796793162 cites W2047690350 @default.
- W2796793162 cites W2047929682 @default.
- W2796793162 cites W2048397134 @default.
- W2796793162 cites W2048490393 @default.
- W2796793162 cites W2049894439 @default.
- W2796793162 cites W2049921929 @default.
- W2796793162 cites W2052998871 @default.
- W2796793162 cites W2057482589 @default.
- W2796793162 cites W2057524700 @default.
- W2796793162 cites W2058933520 @default.
- W2796793162 cites W2060615080 @default.
- W2796793162 cites W2061690253 @default.
- W2796793162 cites W2062097882 @default.
- W2796793162 cites W2062808282 @default.
- W2796793162 cites W2066168089 @default.
- W2796793162 cites W2068323917 @default.
- W2796793162 cites W2074457869 @default.
- W2796793162 cites W2074513890 @default.
- W2796793162 cites W2075199222 @default.
- W2796793162 cites W2078185910 @default.
- W2796793162 cites W2082066180 @default.
- W2796793162 cites W2084501476 @default.
- W2796793162 cites W2089429289 @default.
- W2796793162 cites W2089747890 @default.
- W2796793162 cites W2089960627 @default.
- W2796793162 cites W2092132669 @default.
- W2796793162 cites W2092993578 @default.
- W2796793162 cites W2093354463 @default.
- W2796793162 cites W2094454344 @default.
- W2796793162 cites W2098575356 @default.
- W2796793162 cites W2104497777 @default.
- W2796793162 cites W2105317528 @default.
- W2796793162 cites W2110506825 @default.
- W2796793162 cites W2110839568 @default.