FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2796793721> ?p ?o ?g. }

• W2796793721 endingPage "549" @default.
• W2796793721 startingPage "544" @default.
• W2796793721 abstract "Lactococcus lactis, a gram-positive bacterium, encounters various environmental stresses, especially acid stress, during fermentation. Small RNAs (sRNAs) that serve as regulators at post-transcriptional level play important roles in acid stress response. Here, a novel sRNA S042 was identified by RNA-Seq, RT-PCR and Northern blot. The transcription level of s042 was upregulated 2.29-fold under acid stress by Quantitative RT-PCR (qRT-PCR) analysis. Acid tolerance assay showed that overexpressing s042 increased the survival rate of L. lactis F44 and deleting s042 significantly inhibited the viability under acidic conditions. Moreover, the targets were predicted by online software and four genes were chosen as candidates. Among them, argR (arginine regulator) and accD (acetyl-CoA carboxylase carboxyl transferase subunit beta) were validated to be the direct targets activated by S042 through reporter fusion assay. The regulatory mechanism between S042 and its targets was further investigated through Bioinformatics and qRT-PCR. This study served to highlight the role of the novel sRNA S042 in acid resistance of L. lactis and provided new insights into the response mechanism of acid stress." @default.
• W2796793721 created "2018-04-24" @default.
• W2796793721 creator A5007795002 @default.
• W2796793721 creator A5029337654 @default.
• W2796793721 creator A5032858379 @default.
• W2796793721 creator A5046973356 @default.
• W2796793721 creator A5052751827 @default.
• W2796793721 creator A5056171677 @default.
• W2796793721 creator A5059968598 @default.
• W2796793721 creator A5071029533 @default.
• W2796793721 date "2018-06-01" @default.
• W2796793721 modified "2023-10-15" @default.
• W2796793721 title "A novel small RNA S042 increases acid tolerance in Lactococcus lactis F44" @default.
• W2796793721 cites W1963215147 @default.
• W2796793721 cites W1979442370 @default.
• W2796793721 cites W1986487786 @default.
• W2796793721 cites W1994182220 @default.
• W2796793721 cites W1994508208 @default.
• W2796793721 cites W2000447434 @default.
• W2796793721 cites W2004477120 @default.
• W2796793721 cites W2005440573 @default.
• W2796793721 cites W2008504678 @default.
• W2796793721 cites W2015039594 @default.
• W2796793721 cites W2033557727 @default.
• W2796793721 cites W2044811732 @default.
• W2796793721 cites W2047582118 @default.
• W2796793721 cites W2088710054 @default.
• W2796793721 cites W2106417408 @default.
• W2796793721 cites W2109541103 @default.
• W2796793721 cites W2111508981 @default.
• W2796793721 cites W2131567601 @default.
• W2796793721 cites W2136780020 @default.
• W2796793721 cites W2137293271 @default.
• W2796793721 cites W2143594252 @default.
• W2796793721 cites W2144723744 @default.
• W2796793721 cites W2249732093 @default.
• W2796793721 cites W2294246275 @default.
• W2796793721 cites W2303530292 @default.
• W2796793721 cites W2344754879 @default.
• W2796793721 cites W2415396888 @default.
• W2796793721 cites W2435085820 @default.
• W2796793721 cites W2554101310 @default.
• W2796793721 cites W2633474811 @default.
• W2796793721 cites W2729304259 @default.
• W2796793721 cites W2743239862 @default.
• W2796793721 cites W4230189641 @default.
• W2796793721 doi "https://doi.org/10.1016/j.bbrc.2018.04.069" @default.
• W2796793721 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29654767" @default.
• W2796793721 hasPublicationYear "2018" @default.
• W2796793721 type Work @default.
• W2796793721 sameAs 2796793721 @default.
• W2796793721 citedByCount "5" @default.
• W2796793721 countsByYear W27967937212019 @default.
• W2796793721 countsByYear W27967937212021 @default.
• W2796793721 countsByYear W27967937212022 @default.
• W2796793721 countsByYear W27967937212023 @default.
• W2796793721 crossrefType "journal-article" @default.
• W2796793721 hasAuthorship W2796793721A5007795002 @default.
• W2796793721 hasAuthorship W2796793721A5029337654 @default.
• W2796793721 hasAuthorship W2796793721A5032858379 @default.
• W2796793721 hasAuthorship W2796793721A5046973356 @default.
• W2796793721 hasAuthorship W2796793721A5052751827 @default.
• W2796793721 hasAuthorship W2796793721A5056171677 @default.
• W2796793721 hasAuthorship W2796793721A5059968598 @default.
• W2796793721 hasAuthorship W2796793721A5071029533 @default.
• W2796793721 hasConcept C104317684 @default.
• W2796793721 hasConcept C153911025 @default.
• W2796793721 hasConcept C185592680 @default.
• W2796793721 hasConcept C2775920511 @default.
• W2796793721 hasConcept C2780011460 @default.
• W2796793721 hasConcept C523546767 @default.
• W2796793721 hasConcept C54355233 @default.
• W2796793721 hasConcept C55493867 @default.
• W2796793721 hasConcept C67705224 @default.
• W2796793721 hasConcept C86803240 @default.
• W2796793721 hasConceptScore W2796793721C104317684 @default.
• W2796793721 hasConceptScore W2796793721C153911025 @default.
• W2796793721 hasConceptScore W2796793721C185592680 @default.
• W2796793721 hasConceptScore W2796793721C2775920511 @default.
• W2796793721 hasConceptScore W2796793721C2780011460 @default.
• W2796793721 hasConceptScore W2796793721C523546767 @default.
• W2796793721 hasConceptScore W2796793721C54355233 @default.
• W2796793721 hasConceptScore W2796793721C55493867 @default.
• W2796793721 hasConceptScore W2796793721C67705224 @default.
• W2796793721 hasConceptScore W2796793721C86803240 @default.
• W2796793721 hasFunder F4320321001 @default.
• W2796793721 hasFunder F4320322271 @default.
• W2796793721 hasIssue "3" @default.
• W2796793721 hasLocation W27967937211 @default.
• W2796793721 hasLocation W27967937212 @default.
• W2796793721 hasOpenAccess W2796793721 @default.
• W2796793721 hasPrimaryLocation W27967937211 @default.
• W2796793721 hasRelatedWork W1994548604 @default.
• W2796793721 hasRelatedWork W2009966535 @default.
• W2796793721 hasRelatedWork W2019988726 @default.
• W2796793721 hasRelatedWork W2088063203 @default.
• W2796793721 hasRelatedWork W2130920310 @default.
• W2796793721 hasRelatedWork W2171277769 @default.

• next