Matches in SemOpenAlex for { <https://semopenalex.org/work/W2796906322> ?p ?o ?g. }
- W2796906322 endingPage "206" @default.
- W2796906322 startingPage "206" @default.
- W2796906322 abstract "Feline immunodeficiency virus (FIV) is a naturally-occurring retrovirus that infects domestic and non-domestic feline species, producing progressive immune depletion that results in an acquired immunodeficiency syndrome (AIDS). Much has been learned about FIV since it was first described in 1987, particularly in regard to its application as a model to study the closely related lentivirus, human immunodeficiency virus (HIV). In particular, FIV and HIV share remarkable structure and sequence organization, utilize parallel modes of receptor-mediated entry, and result in a similar spectrum of immunodeficiency-related diseases due to analogous modes of immune dysfunction. This review summarizes current knowledge of FIV infection kinetics and the mechanisms of immune dysfunction in relation to opportunistic disease, specifically in regard to studying HIV pathogenesis. Furthermore, we present data that highlight changes in the oral microbiota and oral immune system during FIV infection, and outline the potential for the feline model of oral AIDS manifestations to elucidate pathogenic mechanisms of HIV-induced oral disease. Finally, we discuss advances in molecular biology, vaccine development, neurologic dysfunction, and the ability to apply pharmacologic interventions and sophisticated imaging technologies to study experimental and naturally occurring FIV, which provide an excellent, but often overlooked, resource for advancing therapies and the management of HIV/AIDS." @default.
- W2796906322 created "2018-04-24" @default.
- W2796906322 creator A5004870248 @default.
- W2796906322 creator A5019088704 @default.
- W2796906322 creator A5033007619 @default.
- W2796906322 creator A5053993900 @default.
- W2796906322 creator A5082164222 @default.
- W2796906322 date "2018-04-20" @default.
- W2796906322 modified "2023-09-26" @default.
- W2796906322 title "Applications of the FIV Model to Study HIV Pathogenesis" @default.
- W2796906322 cites W116619909 @default.
- W2796906322 cites W1480061065 @default.
- W2796906322 cites W1480198977 @default.
- W2796906322 cites W1487893587 @default.
- W2796906322 cites W1514840588 @default.
- W2796906322 cites W1522787357 @default.
- W2796906322 cites W1528520360 @default.
- W2796906322 cites W1530152146 @default.
- W2796906322 cites W1556004468 @default.
- W2796906322 cites W1607122277 @default.
- W2796906322 cites W1608431950 @default.
- W2796906322 cites W1612914901 @default.
- W2796906322 cites W1615449452 @default.
- W2796906322 cites W1616160618 @default.
- W2796906322 cites W1624440538 @default.
- W2796906322 cites W1645801604 @default.
- W2796906322 cites W1659009319 @default.
- W2796906322 cites W1683411584 @default.
- W2796906322 cites W1690665404 @default.
- W2796906322 cites W173133029 @default.
- W2796906322 cites W177107166 @default.
- W2796906322 cites W1817018408 @default.
- W2796906322 cites W1895805806 @default.
- W2796906322 cites W1898743301 @default.
- W2796906322 cites W1909933696 @default.
- W2796906322 cites W1927454462 @default.
- W2796906322 cites W1963580119 @default.
- W2796906322 cites W1964327536 @default.
- W2796906322 cites W1965679910 @default.
- W2796906322 cites W1966278779 @default.
- W2796906322 cites W1966282553 @default.
- W2796906322 cites W1966942276 @default.
- W2796906322 cites W1967258269 @default.
- W2796906322 cites W1971005608 @default.
- W2796906322 cites W1972221169 @default.
- W2796906322 cites W1974096769 @default.
- W2796906322 cites W1974357602 @default.
- W2796906322 cites W1974789987 @default.
- W2796906322 cites W1975904080 @default.
- W2796906322 cites W1977897916 @default.
- W2796906322 cites W1978508935 @default.
- W2796906322 cites W1979016815 @default.
- W2796906322 cites W1979193198 @default.
- W2796906322 cites W1980185182 @default.
- W2796906322 cites W1980417880 @default.
- W2796906322 cites W1981522372 @default.
- W2796906322 cites W1981649984 @default.
- W2796906322 cites W1981685671 @default.
- W2796906322 cites W1986091865 @default.
- W2796906322 cites W1986358866 @default.
- W2796906322 cites W1986455300 @default.
- W2796906322 cites W1987698120 @default.
- W2796906322 cites W1987837574 @default.
- W2796906322 cites W1987971591 @default.
- W2796906322 cites W1988435860 @default.
- W2796906322 cites W1988722391 @default.
- W2796906322 cites W1988940069 @default.
- W2796906322 cites W1988951594 @default.
- W2796906322 cites W1991387601 @default.
- W2796906322 cites W1992991204 @default.
- W2796906322 cites W1993190635 @default.
- W2796906322 cites W1994961277 @default.
- W2796906322 cites W1995018736 @default.
- W2796906322 cites W1995455922 @default.
- W2796906322 cites W1996560705 @default.
- W2796906322 cites W1998754357 @default.
- W2796906322 cites W1999994288 @default.
- W2796906322 cites W2002702640 @default.
- W2796906322 cites W2005515897 @default.
- W2796906322 cites W2006249801 @default.
- W2796906322 cites W2006472249 @default.
- W2796906322 cites W2007837046 @default.
- W2796906322 cites W2008252983 @default.
- W2796906322 cites W2009045705 @default.
- W2796906322 cites W2009204208 @default.
- W2796906322 cites W2009286981 @default.
- W2796906322 cites W2011485991 @default.
- W2796906322 cites W2014282703 @default.
- W2796906322 cites W2014846716 @default.
- W2796906322 cites W2015153666 @default.
- W2796906322 cites W2017710819 @default.
- W2796906322 cites W2018948451 @default.
- W2796906322 cites W2019631946 @default.
- W2796906322 cites W2019885900 @default.
- W2796906322 cites W2019990754 @default.
- W2796906322 cites W2020176314 @default.
- W2796906322 cites W2020673372 @default.
- W2796906322 cites W2020728576 @default.