Matches in SemOpenAlex for { <https://semopenalex.org/work/W2797211914> ?p ?o ?g. }
- W2797211914 abstract "The use of probiotics to improve anti-microbial defence, such as for influenza infections, is increasingly recommended. However, no data are available on the effect of probiotics on flu-associated secondary bacterial infections. There is strong evidence of a spatiotemporal association between influenza virus infection and invasive Neisseria meningitidis. We thus investigated the effect of feeding mice Lactobacillus paracasei CNCM I-1518 in a mouse model of sequential influenza-meningococcal infection. We intranasally infected BALB/c mice with a strain of influenza A virus (IAV) H3N2 that was first adapted to mice. Seven days later, a secondary bacterial infection was induced by intranasal administration of bioluminescent N. meningitidis. During the experiment, mice orally received either L. paracasei CNCM I-1518 or PBS as a control. The effect of L. paracasei administration on secondary bacterial infection by N. meningitidis was evaluated. Oral consumption of L. paracasei CNCM I-1518 reduced the weight loss of infected mice and lowered the bioluminescent signal of infecting meningococci. This improvement was associated with higher recruitment of inflammatory myeloid cells, such as interstitial monocytes and dendritic cells, to the lungs. Our data highlight the role of the gut-lung axis. L. paracasei CNCM I-1518 may boost the defence against IAV infection and secondary bacterial infection, which should be further studied and validated in clinical trials." @default.
- W2797211914 created "2018-04-24" @default.
- W2797211914 creator A5014432588 @default.
- W2797211914 creator A5031844194 @default.
- W2797211914 creator A5088050632 @default.
- W2797211914 date "2018-04-10" @default.
- W2797211914 modified "2023-10-17" @default.
- W2797211914 title "Lactobacillus paracasei feeding improves the control of secondary experimental meningococcal infection in flu-infected mice" @default.
- W2797211914 cites W1482002974 @default.
- W2797211914 cites W1524005751 @default.
- W2797211914 cites W1929917332 @default.
- W2797211914 cites W1986519349 @default.
- W2797211914 cites W1996776152 @default.
- W2797211914 cites W1997990116 @default.
- W2797211914 cites W2017591590 @default.
- W2797211914 cites W2024198983 @default.
- W2797211914 cites W2035242264 @default.
- W2797211914 cites W2036607436 @default.
- W2797211914 cites W2037870996 @default.
- W2797211914 cites W2064954685 @default.
- W2797211914 cites W2073926939 @default.
- W2797211914 cites W2105680176 @default.
- W2797211914 cites W2108100953 @default.
- W2797211914 cites W2110783853 @default.
- W2797211914 cites W2114840397 @default.
- W2797211914 cites W2119403223 @default.
- W2797211914 cites W2146165968 @default.
- W2797211914 cites W2154385325 @default.
- W2797211914 cites W2160005865 @default.
- W2797211914 cites W2160236340 @default.
- W2797211914 cites W2164860726 @default.
- W2797211914 cites W2165029000 @default.
- W2797211914 cites W2168168705 @default.
- W2797211914 cites W2175568660 @default.
- W2797211914 cites W2316490129 @default.
- W2797211914 cites W2416557580 @default.
- W2797211914 cites W2529846237 @default.
- W2797211914 cites W2544851425 @default.
- W2797211914 cites W2557141902 @default.
- W2797211914 cites W2748606547 @default.
- W2797211914 cites W2754161296 @default.
- W2797211914 doi "https://doi.org/10.1186/s12879-018-3086-9" @default.
- W2797211914 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5894232" @default.
- W2797211914 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29636018" @default.
- W2797211914 hasPublicationYear "2018" @default.
- W2797211914 type Work @default.
- W2797211914 sameAs 2797211914 @default.
- W2797211914 citedByCount "11" @default.
- W2797211914 countsByYear W27972119142019 @default.
- W2797211914 countsByYear W27972119142020 @default.
- W2797211914 countsByYear W27972119142021 @default.
- W2797211914 countsByYear W27972119142023 @default.
- W2797211914 crossrefType "journal-article" @default.
- W2797211914 hasAuthorship W2797211914A5014432588 @default.
- W2797211914 hasAuthorship W2797211914A5031844194 @default.
- W2797211914 hasAuthorship W2797211914A5088050632 @default.
- W2797211914 hasBestOaLocation W27972119141 @default.
- W2797211914 hasConcept C159047783 @default.
- W2797211914 hasConcept C190139176 @default.
- W2797211914 hasConcept C203014093 @default.
- W2797211914 hasConcept C2522874641 @default.
- W2797211914 hasConcept C2777546802 @default.
- W2797211914 hasConcept C2778458888 @default.
- W2797211914 hasConcept C2779433226 @default.
- W2797211914 hasConcept C2780206646 @default.
- W2797211914 hasConcept C523546767 @default.
- W2797211914 hasConcept C54355233 @default.
- W2797211914 hasConcept C71924100 @default.
- W2797211914 hasConcept C85663871 @default.
- W2797211914 hasConcept C86803240 @default.
- W2797211914 hasConcept C89423630 @default.
- W2797211914 hasConceptScore W2797211914C159047783 @default.
- W2797211914 hasConceptScore W2797211914C190139176 @default.
- W2797211914 hasConceptScore W2797211914C203014093 @default.
- W2797211914 hasConceptScore W2797211914C2522874641 @default.
- W2797211914 hasConceptScore W2797211914C2777546802 @default.
- W2797211914 hasConceptScore W2797211914C2778458888 @default.
- W2797211914 hasConceptScore W2797211914C2779433226 @default.
- W2797211914 hasConceptScore W2797211914C2780206646 @default.
- W2797211914 hasConceptScore W2797211914C523546767 @default.
- W2797211914 hasConceptScore W2797211914C54355233 @default.
- W2797211914 hasConceptScore W2797211914C71924100 @default.
- W2797211914 hasConceptScore W2797211914C85663871 @default.
- W2797211914 hasConceptScore W2797211914C86803240 @default.
- W2797211914 hasConceptScore W2797211914C89423630 @default.
- W2797211914 hasFunder F4320310065 @default.
- W2797211914 hasFunder F4320322141 @default.
- W2797211914 hasIssue "1" @default.
- W2797211914 hasLocation W27972119141 @default.
- W2797211914 hasLocation W27972119142 @default.
- W2797211914 hasLocation W27972119143 @default.
- W2797211914 hasLocation W27972119144 @default.
- W2797211914 hasLocation W27972119145 @default.
- W2797211914 hasLocation W27972119146 @default.
- W2797211914 hasOpenAccess W2797211914 @default.
- W2797211914 hasPrimaryLocation W27972119141 @default.
- W2797211914 hasRelatedWork W1955099363 @default.
- W2797211914 hasRelatedWork W2001898115 @default.
- W2797211914 hasRelatedWork W2008611427 @default.
- W2797211914 hasRelatedWork W2014699374 @default.