FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2797489511> ?p ?o ?g. }

• W2797489511 endingPage "8650" @default.
• W2797489511 startingPage "8643" @default.
• W2797489511 abstract "GABA C receptors contain ρ subunits and mediate feedback inhibition from retinal amacrine cells to bipolar cells. We previously identified the cytoskeletal protein MAP1B as a ρ1 subunit anchoring protein. Here, we analyze the structural basis and functional significance of the MAP1B-ρ1 interaction. Twelve amino acids at the C terminus of the large intracellular loop of ρ1 (and also ρ2) are sufficient for interaction with MAP1B. Disruption of the MAP1B-ρ interaction in bipolar cells in retinal slices decreased the EC 50 of their GABA C receptors, doubling the receptors' current at low GABA concentrations without affecting their maximum current at high concentrations. Thus, anchoring to the cytoskeleton lowers the sensitivity of GABA C receptors and provides a likely site for functional modulation of GABA C receptor-mediated inhibition." @default.
• W2797489511 created "2018-04-24" @default.
• W2797489511 creator A5020338130 @default.
• W2797489511 creator A5034483380 @default.
• W2797489511 creator A5054589692 @default.
• W2797489511 creator A5084209955 @default.
• W2797489511 creator A5088926573 @default.
• W2797489511 date "2000-12-01" @default.
• W2797489511 modified "2023-10-18" @default.
• W2797489511 title "GABA_CReceptor Sensitivity Is Modulated by Interaction with MAP1B" @default.
• W2797489511 cites W1487317148 @default.
• W2797489511 cites W1523657314 @default.
• W2797489511 cites W1695352463 @default.
• W2797489511 cites W1801516349 @default.
• W2797489511 cites W1829475219 @default.
• W2797489511 cites W1854209661 @default.
• W2797489511 cites W1918496169 @default.
• W2797489511 cites W1941659122 @default.
• W2797489511 cites W1942381117 @default.
• W2797489511 cites W1970310869 @default.
• W2797489511 cites W1971350452 @default.
• W2797489511 cites W1972884505 @default.
• W2797489511 cites W1983738000 @default.
• W2797489511 cites W1984272093 @default.
• W2797489511 cites W1984537495 @default.
• W2797489511 cites W1990266339 @default.
• W2797489511 cites W1992021083 @default.
• W2797489511 cites W2003075703 @default.
• W2797489511 cites W2003563071 @default.
• W2797489511 cites W2004010919 @default.
• W2797489511 cites W2007933423 @default.
• W2797489511 cites W2013253007 @default.
• W2797489511 cites W2015328445 @default.
• W2797489511 cites W2024352808 @default.
• W2797489511 cites W2026559607 @default.
• W2797489511 cites W2032415987 @default.
• W2797489511 cites W2032482854 @default.
• W2797489511 cites W2036685092 @default.
• W2797489511 cites W2039959072 @default.
• W2797489511 cites W2050243692 @default.
• W2797489511 cites W2062564942 @default.
• W2797489511 cites W2063792905 @default.
• W2797489511 cites W2063996780 @default.
• W2797489511 cites W2068446924 @default.
• W2797489511 cites W2075597274 @default.
• W2797489511 cites W2081716375 @default.
• W2797489511 cites W2087034750 @default.
• W2797489511 cites W2090596818 @default.
• W2797489511 cites W2114972922 @default.
• W2797489511 cites W2118922355 @default.
• W2797489511 cites W2127759683 @default.
• W2797489511 cites W2129899041 @default.
• W2797489511 cites W2142036271 @default.
• W2797489511 cites W2144965832 @default.
• W2797489511 cites W2147754580 @default.
• W2797489511 cites W2150986831 @default.
• W2797489511 cites W2156269367 @default.
• W2797489511 cites W2169617962 @default.
• W2797489511 cites W2218111939 @default.
• W2797489511 cites W2307153510 @default.
• W2797489511 cites W2316746025 @default.
• W2797489511 cites W4323238121 @default.
• W2797489511 doi "https://doi.org/10.1523/jneurosci.20-23-08643.2000" @default.
• W2797489511 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6773065" @default.
• W2797489511 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11102469" @default.
• W2797489511 hasPublicationYear "2000" @default.
• W2797489511 type Work @default.
• W2797489511 sameAs 2797489511 @default.
• W2797489511 citedByCount "48" @default.
• W2797489511 countsByYear W27974895112012 @default.
• W2797489511 countsByYear W27974895112013 @default.
• W2797489511 countsByYear W27974895112014 @default.
• W2797489511 countsByYear W27974895112016 @default.
• W2797489511 crossrefType "journal-article" @default.
• W2797489511 hasAuthorship W2797489511A5020338130 @default.
• W2797489511 hasAuthorship W2797489511A5034483380 @default.
• W2797489511 hasAuthorship W2797489511A5054589692 @default.
• W2797489511 hasAuthorship W2797489511A5084209955 @default.
• W2797489511 hasAuthorship W2797489511A5088926573 @default.
• W2797489511 hasBestOaLocation W27974895111 @default.
• W2797489511 hasConcept C104292427 @default.
• W2797489511 hasConcept C104317684 @default.
• W2797489511 hasConcept C12554922 @default.
• W2797489511 hasConcept C142669718 @default.
• W2797489511 hasConcept C1491633281 @default.
• W2797489511 hasConcept C168258287 @default.
• W2797489511 hasConcept C169760540 @default.
• W2797489511 hasConcept C170493617 @default.
• W2797489511 hasConcept C185592680 @default.
• W2797489511 hasConcept C2780827179 @default.
• W2797489511 hasConcept C55493867 @default.
• W2797489511 hasConcept C79879829 @default.
• W2797489511 hasConcept C86803240 @default.
• W2797489511 hasConcept C95444343 @default.
• W2797489511 hasConceptScore W2797489511C104292427 @default.
• W2797489511 hasConceptScore W2797489511C104317684 @default.
• W2797489511 hasConceptScore W2797489511C12554922 @default.
• W2797489511 hasConceptScore W2797489511C142669718 @default.

• next