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• W2797608917 abstract "Searching for bacterial probiotics active upon Helicobacter pylori continue to be an important clinical challenge because of the increased prevalence of this highly priority pathogen in humans. In this work, we assess the in vivo anti-H. pylori SS1 (cagA+/vacAs2m2+) properties of a previously isolated human gastric probiotic strain Lactobacillus fermentum UCO-979C by using a Meriones unguiculatus (Mongolian gerbil) model. Animals were administered with a saline suspension of L. fermentum UCO-979C or H. pylori SS1 as negative and positive control for H. pylori colonisation controls, prior to assayed the challenge group that was administered with these two species per animal for detecting protective activity of the probiotic strain against colonisation. The results showed that L. fermentum UCO-979C strongly inhibited the colonisation of H. pylori decreasing up to 87% of the colonisation in the antrum by the pathogen, suggesting that this probiotic strain has a strong probiotic activity against H. pylori in the most valuable animal model for in vivo assays nowadays." @default.
• W2797608917 created "2018-04-24" @default.
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• W2797608917 date "2018-06-15" @default.
• W2797608917 modified "2023-10-14" @default.
• W2797608917 title "<i>Lactobacillus fermentum</i> UCO-979C strongly inhibited <i>Helicobacter pylori</i> SS1 in <i>Meriones unguiculatus</i>" @default.
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• W2797608917 doi "https://doi.org/10.3920/bm2017.0160" @default.
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