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• W2797712256 abstract "Background: Awareness of the benefits of neoadjuvant therapy is increasing, but its use as an initial therapeutic option for patients with resectable pancreatic cancer remains controversial, especially for those patients without high-risk prognostic features. Even for patients with high-risk features who are candidates to receive neoadjuvant therapy, no standard regimen exists. Methods: In this review, we examined available data on the neoadjuvant therapy in patients with resectable pancreatic cancer, including prospective studies, retrospective studies, and ongoing clinical trials, by searching PubMed/MEDLINE, ClinicalTrials.gov, Web of Science, and Cochrane Library. The characteristics and results of screened studies were described. Results: Retrospective and prospective studies with reported results and ongoing randomized studies were included. For patients with resectable pancreatic cancer, neoadjuvant therapy provides benefits such as increased survival, decreased risk of comorbidities and mortality, and improved cost-effectiveness due to an increased completion rate of multimodal treatment. Highly active regimens such as FOLFIRINOX (folinic acid, fluorouracil, irinotecan, and oxaliplatin) or gemcitabine plus nab-paclitaxel are considered acceptable therapeutic regimens. Additionally, platinum-containing regimens other than FOLFIRINOX are acceptable for selected patients. Other therapies, such as chemoradiation treatment, immuno-oncology agents, and targeted therapies are being explored and the results are highly anticipated. Conclusion: This review highlights the benefits of neoadjuvant therapy for resectable pancreatic cancer. Some regimens are currently acceptable, but need more evidence from well-designed clinical trials or should be used after being carefully examined by a multidisciplinary team." @default.
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• W2797712256 date "2020-01-03" @default.
• W2797712256 modified "2023-10-16" @default.
• W2797712256 title "Neoadjuvant Therapy is Essential for Resectable Pancreatic Cancer" @default.
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• W2797712256 cites W1975153720 @default.
• W2797712256 cites W1985637872 @default.
• W2797712256 cites W1987313243 @default.
• W2797712256 cites W1987355037 @default.
• W2797712256 cites W1990456502 @default.
• W2797712256 cites W1994177577 @default.
• W2797712256 cites W1998149120 @default.
• W2797712256 cites W2003548590 @default.
• W2797712256 cites W2011979258 @default.
• W2797712256 cites W2015943054 @default.
• W2797712256 cites W2015991246 @default.
• W2797712256 cites W2020047150 @default.
• W2797712256 cites W2035281362 @default.
• W2797712256 cites W2043991982 @default.
• W2797712256 cites W2046714873 @default.
• W2797712256 cites W2047318784 @default.
• W2797712256 cites W2056641379 @default.
• W2797712256 cites W2075029857 @default.
• W2797712256 cites W2076878122 @default.
• W2797712256 cites W2079753351 @default.
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• W2797712256 cites W2124427232 @default.
• W2797712256 cites W2132232956 @default.
• W2797712256 cites W2132564070 @default.
• W2797712256 cites W2138582833 @default.
• W2797712256 cites W2145716118 @default.
• W2797712256 cites W2145902876 @default.
• W2797712256 cites W2146468822 @default.
• W2797712256 cites W2149693540 @default.
• W2797712256 cites W2151253787 @default.
• W2797712256 cites W2155637224 @default.
• W2797712256 cites W2158134441 @default.
• W2797712256 cites W2165480504 @default.
• W2797712256 cites W2170202192 @default.
• W2797712256 cites W2176024655 @default.
• W2797712256 cites W2187917981 @default.
• W2797712256 cites W2227346470 @default.
• W2797712256 cites W2272398398 @default.
• W2797712256 cites W2276431092 @default.
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• W2797712256 cites W2512217706 @default.
• W2797712256 cites W2512296211 @default.
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• W2797712256 cites W2553401074 @default.
• W2797712256 cites W2559117888 @default.
• W2797712256 cites W2586745916 @default.
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• W2797712256 cites W2589032550 @default.
• W2797712256 cites W2597657200 @default.
• W2797712256 cites W2606209196 @default.
• W2797712256 cites W2607175459 @default.
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• W2797712256 cites W2742582606 @default.
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• W2797712256 doi "https://doi.org/10.2174/0929867325666180413101722" @default.
• W2797712256 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29651946" @default.
• W2797712256 hasPublicationYear "2020" @default.
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