FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2797905732> ?p ?o ?g. }

• W2797905732 abstract "Cytomegalovirus (CMV) is a ubiquitous infection that causes disease in congenitally infected children and immunocompromised patients. Although nearly all CMV infections remain latent and asymptomatic in immunologically normal individuals, numerous studies have found that systemic viral reactivation is common in immunocompetent critically ill adults, as measured by detection of CMV in the blood (viremia). Furthermore, CMV viremia is strongly correlated with adverse outcomes in the adult intensive care unit (ICU), including prolonged stay, duration of mechanical ventilation, and death. Increasing evidence, including from a randomized clinical trial of antiviral treatment, suggests these effects of CMV may be causal. Therefore, interventions targeting CMV might improve outcomes in adult ICU patients. CMV may have an even greater impact on critically ill children, particularly in low and middle income countries (LMIC), where CMV is regularly acquired in early childhood, and where inpatient morbidity and mortality are inordinately high. However, to date, there are few data regarding the clinical relevance of CMV infection or viremia in immunocompetent critically ill children. We propose that CMV infection should be studied as a potential modifiable cause of disease in critically ill children, and that these studies be conducted in LMIC. Below, we briefly review the role of CMV in immunologically normal critically ill adults and children, outline age-dependent differences in CMV infection that may influence ICU outcomes, and describe an agenda for future research." @default.
• W2797905732 created "2018-04-24" @default.
• W2797905732 creator A5039597079 @default.
• W2797905732 creator A5051394894 @default.
• W2797905732 creator A5061855694 @default.
• W2797905732 creator A5083277386 @default.
• W2797905732 date "2018-04-10" @default.
• W2797905732 modified "2023-10-11" @default.
• W2797905732 title "The Potential Harm of Cytomegalovirus Infection in Immunocompetent Critically Ill Children" @default.
• W2797905732 cites W119877175 @default.
• W2797905732 cites W1515281699 @default.
• W2797905732 cites W1949083656 @default.
• W2797905732 cites W1965810063 @default.
• W2797905732 cites W1966990865 @default.
• W2797905732 cites W1967137104 @default.
• W2797905732 cites W1969739923 @default.
• W2797905732 cites W1970900106 @default.
• W2797905732 cites W1974647054 @default.
• W2797905732 cites W1976978388 @default.
• W2797905732 cites W1978297432 @default.
• W2797905732 cites W1987005103 @default.
• W2797905732 cites W1993289663 @default.
• W2797905732 cites W1994745370 @default.
• W2797905732 cites W1998427452 @default.
• W2797905732 cites W2001460749 @default.
• W2797905732 cites W2011771801 @default.
• W2797905732 cites W2014634372 @default.
• W2797905732 cites W2015681499 @default.
• W2797905732 cites W2020381478 @default.
• W2797905732 cites W2023582820 @default.
• W2797905732 cites W2026932586 @default.
• W2797905732 cites W2028978159 @default.
• W2797905732 cites W2043570079 @default.
• W2797905732 cites W2046977851 @default.
• W2797905732 cites W2049215154 @default.
• W2797905732 cites W2060843008 @default.
• W2797905732 cites W2064459441 @default.
• W2797905732 cites W2064464655 @default.
• W2797905732 cites W2070057838 @default.
• W2797905732 cites W2072562300 @default.
• W2797905732 cites W2072796561 @default.
• W2797905732 cites W2072831620 @default.
• W2797905732 cites W2073056065 @default.
• W2797905732 cites W2073569962 @default.
• W2797905732 cites W2073890129 @default.
• W2797905732 cites W2074200017 @default.
• W2797905732 cites W2075549751 @default.
• W2797905732 cites W2077726738 @default.
• W2797905732 cites W2081175226 @default.
• W2797905732 cites W2084192059 @default.
• W2797905732 cites W2084907313 @default.
• W2797905732 cites W2091704657 @default.
• W2797905732 cites W2092958052 @default.
• W2797905732 cites W2093931967 @default.
• W2797905732 cites W2095200251 @default.
• W2797905732 cites W2096233660 @default.
• W2797905732 cites W2099400163 @default.
• W2797905732 cites W2100283908 @default.
• W2797905732 cites W2102252998 @default.
• W2797905732 cites W2103219310 @default.
• W2797905732 cites W2103794276 @default.
• W2797905732 cites W2114635506 @default.
• W2797905732 cites W2116687125 @default.
• W2797905732 cites W2118382376 @default.
• W2797905732 cites W2124696813 @default.
• W2797905732 cites W2125553232 @default.
• W2797905732 cites W2127894722 @default.
• W2797905732 cites W2131480973 @default.
• W2797905732 cites W2131841740 @default.
• W2797905732 cites W2140268741 @default.
• W2797905732 cites W2142376911 @default.
• W2797905732 cites W2143012846 @default.
• W2797905732 cites W2144052741 @default.
• W2797905732 cites W2153057126 @default.
• W2797905732 cites W2153066661 @default.
• W2797905732 cites W2161374626 @default.
• W2797905732 cites W2163053457 @default.
• W2797905732 cites W2163649648 @default.
• W2797905732 cites W2164608402 @default.
• W2797905732 cites W2164613060 @default.
• W2797905732 cites W2165232639 @default.
• W2797905732 cites W2166380585 @default.
• W2797905732 cites W2167932549 @default.
• W2797905732 cites W2171016993 @default.
• W2797905732 cites W2192795845 @default.
• W2797905732 cites W2226792000 @default.
• W2797905732 cites W2282286414 @default.
• W2797905732 cites W2283669950 @default.
• W2797905732 cites W2343060625 @default.
• W2797905732 cites W2344294128 @default.
• W2797905732 cites W2416273423 @default.
• W2797905732 cites W2462318560 @default.
• W2797905732 cites W2519905418 @default.
• W2797905732 cites W2525673231 @default.
• W2797905732 cites W2527549642 @default.
• W2797905732 cites W2546536208 @default.
• W2797905732 cites W2547341976 @default.
• W2797905732 cites W2559982370 @default.
• W2797905732 cites W2586233372 @default.
• W2797905732 cites W2588030598 @default.

• next