FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2799391388> ?p ?o ?g. }

• W2799391388 endingPage "1960" @default.
• W2799391388 startingPage "1953" @default.
• W2799391388 abstract "Acute kidney injury (AKI) is a critical determinant of outcomes in hospitalized patients with cirrhosis, but little is known of the impact of AKI in the outpatient setting. We analyzed 385 adult outpatients with cirrhosis listed for liver transplant at a single center; excluded were those with severe hepatic encephalopathy, with hepatocellular carcinoma, or on hemodialysis. Baseline serum creatinine (bCr) was defined as the lowest value recorded, peak Cr as the highest value, ΔCr as peak Cr minus bCr, AKI as a rise in serum Cr (sCr) by ≥0.3 mg/dL from bCr, persistent kidney injury as elevation of sCR by ≥0.3 mg/dL from bCr on each subsequent clinical assessment. Among 385 outpatients with cirrhosis, bCr was ≤0.70, 0.70-0.97, and ≥0.97 mg/dL in 28%, 38%, and 34%, respectively. At a median follow-up of 16 (range 8-28) months, 143 (37%) had one or more AKI episode, which increased significantly by bCr group (24% versus 37% versus 48%, P = 0.001). Of these 143 with AKI, 13% developed persistent kidney injury. A multivariable Cox regression analysis highlighted that bCr (hazard ratio [HR], 2.96) and ΔCr (HR, 2.05) were the only factors independently associated with the development of persistent kidney injury (P < 0.001). The likelihood of death/delisting increased by bCr group (14% versus 19% versus 28%, P = 0.03). A competing risk analysis demonstrated that each 1 mg/dL increase in bCr was independently associated with a 62% higher risk of death/delisting when accounting for transplantation and adjusting for confounders. Conclusion: AKI is not only common in outpatients with cirrhosis but even clinically normal bCr levels significantly impact the risk of persistent kidney injury and waitlist mortality, supporting the need for a lower clinical threshold to initiate monitoring of renal function and implementation of kidney-protective strategies." @default.
• W2799391388 created "2018-05-17" @default.
• W2799391388 creator A5006153810 @default.
• W2799391388 creator A5009011740 @default.
• W2799391388 creator A5076488821 @default.
• W2799391388 date "2018-07-10" @default.
• W2799391388 modified "2023-09-26" @default.
• W2799391388 title "“Normal” Creatinine Levels Predict Persistent Kidney Injury and Waitlist Mortality in Outpatients With Cirrhosis" @default.
• W2799391388 cites W1850203179 @default.
• W2799391388 cites W1940450382 @default.
• W2799391388 cites W1967890992 @default.
• W2799391388 cites W1975587900 @default.
• W2799391388 cites W1988039564 @default.
• W2799391388 cites W1997855605 @default.
• W2799391388 cites W2011458442 @default.
• W2799391388 cites W2012746560 @default.
• W2799391388 cites W2020128905 @default.
• W2799391388 cites W2043539888 @default.
• W2799391388 cites W2053554521 @default.
• W2799391388 cites W2055864845 @default.
• W2799391388 cites W2061670714 @default.
• W2799391388 cites W2067759325 @default.
• W2799391388 cites W2077014158 @default.
• W2799391388 cites W2094608506 @default.
• W2799391388 cites W2109355833 @default.
• W2799391388 cites W2110280698 @default.
• W2799391388 cites W2128352204 @default.
• W2799391388 cites W2131389007 @default.
• W2799391388 cites W2155965977 @default.
• W2799391388 cites W2157556100 @default.
• W2799391388 cites W2300413642 @default.
• W2799391388 cites W2322673970 @default.
• W2799391388 cites W2565339423 @default.
• W2799391388 cites W2606209221 @default.
• W2799391388 cites W2607031541 @default.
• W2799391388 cites W2608770331 @default.
• W2799391388 cites W2622632860 @default.
• W2799391388 cites W4211185450 @default.
• W2799391388 doi "https://doi.org/10.1002/hep.30058" @default.
• W2799391388 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6203679" @default.
• W2799391388 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29698588" @default.
• W2799391388 hasPublicationYear "2018" @default.
• W2799391388 type Work @default.
• W2799391388 sameAs 2799391388 @default.
• W2799391388 citedByCount "30" @default.
• W2799391388 countsByYear W27993913882019 @default.
• W2799391388 countsByYear W27993913882020 @default.
• W2799391388 countsByYear W27993913882021 @default.
• W2799391388 countsByYear W27993913882022 @default.
• W2799391388 countsByYear W27993913882023 @default.
• W2799391388 crossrefType "journal-article" @default.
• W2799391388 hasAuthorship W2799391388A5006153810 @default.
• W2799391388 hasAuthorship W2799391388A5009011740 @default.
• W2799391388 hasAuthorship W2799391388A5076488821 @default.
• W2799391388 hasBestOaLocation W27993913881 @default.
• W2799391388 hasConcept C126322002 @default.
• W2799391388 hasConcept C159641895 @default.
• W2799391388 hasConcept C207103383 @default.
• W2799391388 hasConcept C2777214474 @default.
• W2799391388 hasConcept C2778019345 @default.
• W2799391388 hasConcept C2778063415 @default.
• W2799391388 hasConcept C2780306776 @default.
• W2799391388 hasConcept C2780472472 @default.
• W2799391388 hasConcept C44249647 @default.
• W2799391388 hasConcept C50382708 @default.
• W2799391388 hasConcept C71924100 @default.
• W2799391388 hasConcept C90924648 @default.
• W2799391388 hasConceptScore W2799391388C126322002 @default.
• W2799391388 hasConceptScore W2799391388C159641895 @default.
• W2799391388 hasConceptScore W2799391388C207103383 @default.
• W2799391388 hasConceptScore W2799391388C2777214474 @default.
• W2799391388 hasConceptScore W2799391388C2778019345 @default.
• W2799391388 hasConceptScore W2799391388C2778063415 @default.
• W2799391388 hasConceptScore W2799391388C2780306776 @default.
• W2799391388 hasConceptScore W2799391388C2780472472 @default.
• W2799391388 hasConceptScore W2799391388C44249647 @default.
• W2799391388 hasConceptScore W2799391388C50382708 @default.
• W2799391388 hasConceptScore W2799391388C71924100 @default.
• W2799391388 hasConceptScore W2799391388C90924648 @default.
• W2799391388 hasIssue "5" @default.
• W2799391388 hasLocation W27993913881 @default.
• W2799391388 hasLocation W27993913882 @default.
• W2799391388 hasLocation W27993913883 @default.
• W2799391388 hasLocation W27993913884 @default.
• W2799391388 hasOpenAccess W2799391388 @default.
• W2799391388 hasPrimaryLocation W27993913881 @default.
• W2799391388 hasRelatedWork W2034000389 @default.
• W2799391388 hasRelatedWork W2148441798 @default.
• W2799391388 hasRelatedWork W2255318257 @default.
• W2799391388 hasRelatedWork W2266860383 @default.
• W2799391388 hasRelatedWork W2324406516 @default.
• W2799391388 hasRelatedWork W2362520236 @default.
• W2799391388 hasRelatedWork W2412677110 @default.
• W2799391388 hasRelatedWork W2766588635 @default.
• W2799391388 hasRelatedWork W3030449887 @default.
• W2799391388 hasRelatedWork W4220700002 @default.
• W2799391388 hasVolume "68" @default.
• W2799391388 isParatext "false" @default.

• next