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• W2799404500 abstract "The genus Commiphora has been widely used in traditional medicinal systems to treat pain, skin infections, diarrhoea and periodontal diseases. Oleo-gum resins of seven Commiphora species (C. myrrha, C. confusa, C. baluensis, C. pseudopaolii, C. guidotti, C. holtziana and C. kataf) were collected from Kenya and Ethiopia. Headspace analysis was determined using GCxGC–ToF–MS. In vitro evaluation of antimicrobial activity of acetone extracts were evaluated against a range of micro-organisms using microdilution assay. In addition, anti-quorum sensing activity of the tested Commiphora species was assessed qualitatively and quantitatively using Chromobacterium violaceum strain. α-Pinene (5.6–8.1%), β-caryophyllene (nd-16.5%), cis-β-ocimene (nd-7.4%), α-santalene (nd-40.8%), α-bourbonene (6.9–37.4%), β-elemene (nd-26.2%), curzerene (4.5–8.2%), p-cymene (1.8–54.5%), curzerenone (1.6–25.5%), (Z)-α-bisabolene (nd-10.4%), β-selinene (nd-9.8%), germacrene D (nd-8.4%), cresol methyl ether (nd-8.5%), 7-epi-sesquithujene (nd-8.8%), dehydro-aromadendrene (nd-36.9%), δ-elemene (nd-31.1%) and spathulenol (0.2–10.4%) were the major volatile constituents. Principal component analysis showed three clusters corresponding to three chemotypes within the dataset. The extracts exhibited good to moderate antibacterial activity against a panel of selected micro-organisms (MIC values: 0.06–8.0 mg/mL). Commiphora holtziana displayed the best activity against Candida tropicalis (0.06–4.0 mg/mL), while C. holtziana and C. myrrha exhibited the best anti-quorum sensing activity by inhibiting violacein production." @default.
• W2799404500 created "2018-05-17" @default.
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• W2799404500 date "2019-05-01" @default.
• W2799404500 modified "2023-09-30" @default.
• W2799404500 title "Headspace analysis, antimicrobial and anti-quorum sensing activities of seven selected African Commiphora species" @default.
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• W2799404500 doi "https://doi.org/10.1016/j.sajb.2018.03.001" @default.
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