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• W2799453465 abstract "<p><strong>Introduction: </strong>Recruiting racial, ethnic, and other underserved minorities into conven­tional clinic-based and other trials is known to be challenging. The Sistas Inspiring Sistas Through Activity and Support (SISTAS) Pro­gram was a one-year randomized controlled trial (RCT) to promote physical activity and healthy eating among AA women in SC to reduce inflammatory biomarkers, which are linked to increased breast cancer (BrCa) risk and mortality. This study describes the development, recruitment, and imple­mentation of the SISTAS clinical trial and provides baseline characteristics of the study participants.</p><p><strong>Methods: </strong>SISTAS was developed using community-based participatory research (CBPR) approaches. At baseline, study participants completed assessments and underwent clinical measurements and blood draws to measure C-reactive protein (CRP) and interleukin-6 (IL-6). Participants randomized to the intervention received 12 weekly classes followed by nine monthly booster sessions. Post-intervention mea­surements were assessed at 12-week and 12-month follow-ups.</p><p><strong>Results: </strong>We recruited a total of 337 women who tended to: be middle-aged (mean age 48.2 years); have some college education; be employed full-time; have Medicare as their primary insurance; be non-smokers; and perceive their personal health as good. On average, the women were pre-hyper­tensive at baseline (mean systolic blood pressure = 133.9 mm Hg; mean diastolic blood pressure = 84.0 mm Hg) and mor­bidly obese (mean BMI &gt;40.0 kg/m2); the mean fat mass and fat-free mass among participants were 106.4 lb and 121.0 lb, respectively.</p><p><strong>Conclusion: </strong>The SISTAS RCT addresses some of the gaps in the literature with respect to CBPR interventions target­ing AA women, such as implementing diet and physical activity in CBPR-based studies to decrease BrCa risk.</p><p><em>Ethn Dis. </em>2018;28(2):75-84; doi:10.18865/ ed.28.2.75.</p>" @default.
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• W2799453465 date "2018-04-26" @default.
• W2799453465 modified "2023-09-22" @default.
• W2799453465 title "Sistas Inspiring Sistas Through Activity and Support (SISTAS): Study Design and Demographics of Participants" @default.
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• W2799453465 doi "https://doi.org/10.18865/ed.28.2.75" @default.
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