FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2799651344> ?p ?o ?g. }

• W2799651344 endingPage "626" @default.
• W2799651344 startingPage "620" @default.
• W2799651344 abstract "Non‐syndromic cleft lip with or without cleft palate ( NSCL /P) is a complex disorder, and it results from both of the genetic modifiers and environmental factors, with genetic modifiers contributes to it more than environmental factors. GWASs made great progress in identifying the candidate genes for NSCL /P, but the findings need to be replicated in other populations. In this study, we selected eleven SNP s from recent GWAS s and GWAS meta‐analysis to investigate their associations among 308 NSCL /P trios (134 non‐syndromic cleft lip only ( NSCLO ) trios and 174 non‐syndromic cleft lip with cleft palate ( NSCLP ) trios) from Han Chinese population. All SNP s were genotyped using SNP scan method and analyzed the data with FBAT , PLINK , and R package. Allelic TDT analysis showed that allele A at rs12543318 was associated with NSCLO trios ( P = .0032, OR = 0.57, 95% CI : 0.39‐0.83), and parent‐of‐origin effect analysis indicated that allele A at rs12543318 was significantly maternally undertransmitted among NSCLO ( P = .0046), which implied the potential influence of genomic imprinting; global TDT further confirmed this association. Individual genotypic TDT showed homozygote C/C at rs12543318 was overtransmitted among NSCLO (Z = 3.79, P = .00015) and NSCL /P groups (Z = 3.83, P = .00013), which indicated that it could increase the risk to have cleft babies. Our findings indicated that rs12543318 was associated with NSCLO from Western Han Chinese population, which will give new scientific evidence for later researches in the etiology of NSOC s." @default.
• W2799651344 created "2018-05-17" @default.
• W2799651344 creator A5016506282 @default.
• W2799651344 creator A5029130019 @default.
• W2799651344 creator A5082743889 @default.
• W2799651344 creator A5084104270 @default.
• W2799651344 creator A5084176696 @default.
• W2799651344 date "2018-05-30" @default.
• W2799651344 modified "2023-09-26" @default.
• W2799651344 title "Homozygote C/C at rs12543318 was risk factor for non-syndromic cleft lip only from Western Han Chinese population" @default.
• W2799651344 cites W1554432647 @default.
• W2799651344 cites W1688394263 @default.
• W2799651344 cites W1754260787 @default.
• W2799651344 cites W1910092612 @default.
• W2799651344 cites W1964690949 @default.
• W2799651344 cites W1968344288 @default.
• W2799651344 cites W1973123998 @default.
• W2799651344 cites W1977920130 @default.
• W2799651344 cites W2005122856 @default.
• W2799651344 cites W2009010101 @default.
• W2799651344 cites W2022066446 @default.
• W2799651344 cites W2024791049 @default.
• W2799651344 cites W2037482745 @default.
• W2799651344 cites W2060683299 @default.
• W2799651344 cites W2088287802 @default.
• W2799651344 cites W2091853774 @default.
• W2799651344 cites W2106753656 @default.
• W2799651344 cites W2132491358 @default.
• W2799651344 cites W2137948811 @default.
• W2799651344 cites W2144067546 @default.
• W2799651344 cites W2161633633 @default.
• W2799651344 cites W2162574600 @default.
• W2799651344 cites W2169807842 @default.
• W2799651344 cites W2307675788 @default.
• W2799651344 cites W2570434836 @default.
• W2799651344 cites W2590327141 @default.
• W2799651344 cites W2783159510 @default.
• W2799651344 doi "https://doi.org/10.1111/jop.12719" @default.
• W2799651344 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29683526" @default.
• W2799651344 hasPublicationYear "2018" @default.
• W2799651344 type Work @default.
• W2799651344 sameAs 2799651344 @default.
• W2799651344 citedByCount "3" @default.
• W2799651344 countsByYear W27996513442019 @default.
• W2799651344 countsByYear W27996513442020 @default.
• W2799651344 countsByYear W27996513442022 @default.
• W2799651344 crossrefType "journal-article" @default.
• W2799651344 hasAuthorship W2799651344A5016506282 @default.
• W2799651344 hasAuthorship W2799651344A5029130019 @default.
• W2799651344 hasAuthorship W2799651344A5082743889 @default.
• W2799651344 hasAuthorship W2799651344A5084104270 @default.
• W2799651344 hasAuthorship W2799651344A5084176696 @default.
• W2799651344 hasConcept C104317684 @default.
• W2799651344 hasConcept C106208931 @default.
• W2799651344 hasConcept C135763542 @default.
• W2799651344 hasConcept C139275648 @default.
• W2799651344 hasConcept C153209595 @default.
• W2799651344 hasConcept C180754005 @default.
• W2799651344 hasConcept C186413461 @default.
• W2799651344 hasConcept C2908647359 @default.
• W2799651344 hasConcept C3020469904 @default.
• W2799651344 hasConcept C3020640247 @default.
• W2799651344 hasConcept C54355233 @default.
• W2799651344 hasConcept C71924100 @default.
• W2799651344 hasConcept C86803240 @default.
• W2799651344 hasConcept C99454951 @default.
• W2799651344 hasConceptScore W2799651344C104317684 @default.
• W2799651344 hasConceptScore W2799651344C106208931 @default.
• W2799651344 hasConceptScore W2799651344C135763542 @default.
• W2799651344 hasConceptScore W2799651344C139275648 @default.
• W2799651344 hasConceptScore W2799651344C153209595 @default.
• W2799651344 hasConceptScore W2799651344C180754005 @default.
• W2799651344 hasConceptScore W2799651344C186413461 @default.
• W2799651344 hasConceptScore W2799651344C2908647359 @default.
• W2799651344 hasConceptScore W2799651344C3020469904 @default.
• W2799651344 hasConceptScore W2799651344C3020640247 @default.
• W2799651344 hasConceptScore W2799651344C54355233 @default.
• W2799651344 hasConceptScore W2799651344C71924100 @default.
• W2799651344 hasConceptScore W2799651344C86803240 @default.
• W2799651344 hasConceptScore W2799651344C99454951 @default.
• W2799651344 hasIssue "6" @default.
• W2799651344 hasLocation W27996513441 @default.
• W2799651344 hasLocation W27996513442 @default.
• W2799651344 hasOpenAccess W2799651344 @default.
• W2799651344 hasPrimaryLocation W27996513441 @default.
• W2799651344 hasRelatedWork W1965339479 @default.
• W2799651344 hasRelatedWork W1990198259 @default.
• W2799651344 hasRelatedWork W2065120962 @default.
• W2799651344 hasRelatedWork W2091652509 @default.
• W2799651344 hasRelatedWork W2587112589 @default.
• W2799651344 hasRelatedWork W3081400219 @default.
• W2799651344 hasRelatedWork W3117480659 @default.
• W2799651344 hasRelatedWork W3125099908 @default.
• W2799651344 hasRelatedWork W3132297604 @default.
• W2799651344 hasRelatedWork W418801207 @default.
• W2799651344 hasVolume "47" @default.
• W2799651344 isParatext "false" @default.
• W2799651344 isRetracted "false" @default.

• next