Matches in SemOpenAlex for { <https://semopenalex.org/work/W2799681600> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W2799681600 endingPage "617" @default.
- W2799681600 startingPage "610" @default.
- W2799681600 abstract "Functional dyspepsia (FD) is a set of relapsing or chronic dyspeptic symptoms in the absence of structural organic lesions. Approximately 15-20% of the general population in many developed countries suffers from dyspeptic symptoms at any time in a year, whereas in Pakistan, 14-22 % of general population suffers from FD. Objective: This study was designed to evaluate the effectiveness of carica papaya extract (CP) in preventing functional dyspepsia in human volunteers.Methodology: A community based, placebo-controlled, double -blind, multi-centered, and randomized clinical trial through systematic random sampling was conducted in Lahore urban community. After initial diagnostic investigations in 200 patients diagnosed as cases of FD fulfilling Rome III criteria were recruitedafter taking written consent and randomly assigned to one of 2 treatment groups (CP extract group or placebo) in equal number. A 7 days medication free period was observed before the start of trial. Each patient received the treatment for 6 weeks. The primary outcome variable was the improvement in gastrointestinalsymptom score (GIS) consisting of evaluation of 10 dyspeptic symptoms rated on Likert scale. Dyspeptic symptoms were assessed at the start of trial then after 2, 4 and 6 weeks. Results: In this trial, 200 patients fully participated in this study (age 36.31±9.711 years, range 18-55, 60% female). Compared with placebo, Carica papaya extract (CP group) showed a clinically significant improvement. The GIS significantly decreased in CP group during the first 2 weeks, compared to the placebo (p < 0.05). During the second and third 2-week period, symptoms further improved in CP group (p < 0.05). After 6 weeks, 95.7% on CP treatment and 3.1% on placebo were completely relieved of FD symptoms (p < 0.001). Conclusions: CP extract was significantly effective gastro-protective as compared with placebo." @default.
- W2799681600 created "2018-05-17" @default.
- W2799681600 creator A5025058372 @default.
- W2799681600 creator A5077694562 @default.
- W2799681600 creator A5087996651 @default.
- W2799681600 date "2018-03-31" @default.
- W2799681600 modified "2023-09-24" @default.
- W2799681600 title "Prevention of Functional Dyspepsia with Carica Papaya Extract" @default.
- W2799681600 doi "https://doi.org/10.21649/akemu.v24i1.2322" @default.
- W2799681600 hasPublicationYear "2018" @default.
- W2799681600 type Work @default.
- W2799681600 sameAs 2799681600 @default.
- W2799681600 citedByCount "0" @default.
- W2799681600 crossrefType "journal-article" @default.
- W2799681600 hasAuthorship W2799681600A5025058372 @default.
- W2799681600 hasAuthorship W2799681600A5077694562 @default.
- W2799681600 hasAuthorship W2799681600A5087996651 @default.
- W2799681600 hasBestOaLocation W27996816001 @default.
- W2799681600 hasConcept C126322002 @default.
- W2799681600 hasConcept C142724271 @default.
- W2799681600 hasConcept C144027150 @default.
- W2799681600 hasConcept C168563851 @default.
- W2799681600 hasConcept C1862650 @default.
- W2799681600 hasConcept C204787440 @default.
- W2799681600 hasConcept C27081682 @default.
- W2799681600 hasConcept C2779231358 @default.
- W2799681600 hasConcept C2908647359 @default.
- W2799681600 hasConcept C535046627 @default.
- W2799681600 hasConcept C556039675 @default.
- W2799681600 hasConcept C68122502 @default.
- W2799681600 hasConcept C71924100 @default.
- W2799681600 hasConcept C86803240 @default.
- W2799681600 hasConcept C99454951 @default.
- W2799681600 hasConceptScore W2799681600C126322002 @default.
- W2799681600 hasConceptScore W2799681600C142724271 @default.
- W2799681600 hasConceptScore W2799681600C144027150 @default.
- W2799681600 hasConceptScore W2799681600C168563851 @default.
- W2799681600 hasConceptScore W2799681600C1862650 @default.
- W2799681600 hasConceptScore W2799681600C204787440 @default.
- W2799681600 hasConceptScore W2799681600C27081682 @default.
- W2799681600 hasConceptScore W2799681600C2779231358 @default.
- W2799681600 hasConceptScore W2799681600C2908647359 @default.
- W2799681600 hasConceptScore W2799681600C535046627 @default.
- W2799681600 hasConceptScore W2799681600C556039675 @default.
- W2799681600 hasConceptScore W2799681600C68122502 @default.
- W2799681600 hasConceptScore W2799681600C71924100 @default.
- W2799681600 hasConceptScore W2799681600C86803240 @default.
- W2799681600 hasConceptScore W2799681600C99454951 @default.
- W2799681600 hasIssue "1" @default.
- W2799681600 hasLocation W27996816001 @default.
- W2799681600 hasOpenAccess W2799681600 @default.
- W2799681600 hasPrimaryLocation W27996816001 @default.
- W2799681600 hasRelatedWork W1510511771 @default.
- W2799681600 hasRelatedWork W1982061982 @default.
- W2799681600 hasRelatedWork W2100747015 @default.
- W2799681600 hasRelatedWork W2147123403 @default.
- W2799681600 hasRelatedWork W2155338253 @default.
- W2799681600 hasRelatedWork W2507295142 @default.
- W2799681600 hasRelatedWork W2770414050 @default.
- W2799681600 hasRelatedWork W3090525104 @default.
- W2799681600 hasRelatedWork W3159250744 @default.
- W2799681600 hasRelatedWork W4233016836 @default.
- W2799681600 hasVolume "24" @default.
- W2799681600 isParatext "false" @default.
- W2799681600 isRetracted "false" @default.
- W2799681600 magId "2799681600" @default.
- W2799681600 workType "article" @default.