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- W2800010118 abstract "Diabetes mellitus is a metabolic disease with high prevalence in Indonesia (5,8%) for the age range 20-79. Diabetic patients were 9 million and 4,8 million patients for undiagnosed case.It was predicted would be 21,3 million patients at 2030 and increased about 10,1% at 2035. The three herbal is mengkudu fruits (Morinda citrifolia L.), fenugreek seeds (Trigonella foenum-graecum L.), and black seed (Nigella sativa L.) which their antidiabetic properties are already confirmed. The present study is to determined variation dosage which have the best antidiabetic activity of three polyherbal combination in rats with alloxan induced method. The rats were divided into six groups receiving different treatment consisting of three various dose of combination ethanolic extract, placebo and standard antidiabetic drugs glibenclamide (0,45mg/kg bw). The result showed the test group II consisting poly herbal combination ethanolic extract of dose 500 mg/kg bw mengkudu fruits, 1000 mg/kg bw fenugreek seeds, and 1000 mg/kg bw black seed has the best activity on decreasing blood glucose level diabetic rats is 66,33% . Key words : Antidiabetic, polyherbal combination" @default.
- W2800010118 created "2018-05-17" @default.
- W2800010118 creator A5081077412 @default.
- W2800010118 date "2017-08-22" @default.
- W2800010118 modified "2023-09-24" @default.
- W2800010118 title "POLY HERBAL COMBINATION ANTIDIABETIC ACTIVITY ETHANOLIC EXTRACT OF FENUGREEK SEEDS (Trigonella foenum-graecum L.) MENGKUDU FRUITS (Morinda citrifolia L.) AND BLACK SEED (Nigella sativa L.) IN RATS INDUCED ALLOXAN" @default.
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