FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2800107466> ?p ?o ?g. }

• W2800107466 endingPage "e0196613" @default.
• W2800107466 startingPage "e0196613" @default.
• W2800107466 abstract "Introduction Objective was to examine the temporal variation of HIV sero-discordancy in select representative countries (Kenya, Lesotho, Mali, Niger, Tanzania, and Zimbabwe) in sub-Saharan Africa at different HIV epidemic scales. A sero-discordant couple is defined as a stable couple (SC) in which one partner is HIV-positive while the other is HIV-negative. Methods A deterministic compartmental mathematical model was constructed to describe HIV transmission dynamics. The model was pair-based, that is explicitly modeling formation of SCs and infection dynamics in both SCs and in single individuals. The model accommodated for different forms of infection statuses in SCs. Using population-based nationally-representative epidemiologic and demographic input data, historical (1980–2014) and future (2015–2030) trends of sero-discordancy and other demographic and epidemiologic indicators were projected throughout HIV epidemic phases. Results As the epidemics emerged, about 90% of SCs affected by HIV were sero-discordant. This proportion declined to 45%-88% at epidemic peak and stabilized as the epidemics started their natural decline. The largest reductions in sero-discordancy were in high HIV-prevalence countries. As the epidemics further declined with antiretroviral therapy (ART) scale-up, the proportion of sero-discordant couples among HIV-affected couples was projected to increase to 70%-92% by 2030. The proportion of sero-discordant couples among all SCs increased as the epidemics emerged and evolved, then peaked at 2%-20% as the epidemics peaked, and then declined as the epidemics declined to reach 0.3%-16% by 2030. Conclusions Sero-discordancy patterns varied with the evolution of the epidemics, and were affected by both epidemic phase and scale. The largest variations were found in high HIV-prevalence countries. The fraction of stable couples that are sero-discordant, as opposed to being sero-concordant positive, was projected to increase with ART scale-up and further HIV incidence decline over the coming two decades. These findings inform strategic planning and resource allocation for interventions among sero-discordant couples." @default.
• W2800107466 created "2018-05-17" @default.
• W2800107466 creator A5014846631 @default.
• W2800107466 creator A5030911148 @default.
• W2800107466 creator A5064185123 @default.
• W2800107466 date "2018-04-30" @default.
• W2800107466 modified "2023-09-26" @default.
• W2800107466 title "Temporal evolution of HIV sero-discordancy patterns among stable couples in sub-Saharan Africa" @default.
• W2800107466 cites W1809225310 @default.
• W2800107466 cites W1982709905 @default.
• W2800107466 cites W1994333367 @default.
• W2800107466 cites W1995476723 @default.
• W2800107466 cites W2001220325 @default.
• W2800107466 cites W2001276390 @default.
• W2800107466 cites W2004901810 @default.
• W2800107466 cites W2011380918 @default.
• W2800107466 cites W2036210112 @default.
• W2800107466 cites W2038051569 @default.
• W2800107466 cites W2041365263 @default.
• W2800107466 cites W2048021429 @default.
• W2800107466 cites W2065995052 @default.
• W2800107466 cites W2068164202 @default.
• W2800107466 cites W2099048494 @default.
• W2800107466 cites W2100430786 @default.
• W2800107466 cites W2106363895 @default.
• W2800107466 cites W2122193492 @default.
• W2800107466 cites W2133720861 @default.
• W2800107466 cites W2135007006 @default.
• W2800107466 cites W2136264966 @default.
• W2800107466 cites W2152505869 @default.
• W2800107466 cites W2220552627 @default.
• W2800107466 cites W2243750532 @default.
• W2800107466 cites W2513172977 @default.
• W2800107466 doi "https://doi.org/10.1371/journal.pone.0196613" @default.
• W2800107466 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5927442" @default.
• W2800107466 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29708995" @default.
• W2800107466 hasPublicationYear "2018" @default.
• W2800107466 type Work @default.
• W2800107466 sameAs 2800107466 @default.
• W2800107466 citedByCount "1" @default.
• W2800107466 countsByYear W28001074662023 @default.
• W2800107466 crossrefType "journal-article" @default.
• W2800107466 hasAuthorship W2800107466A5014846631 @default.
• W2800107466 hasAuthorship W2800107466A5030911148 @default.
• W2800107466 hasAuthorship W2800107466A5064185123 @default.
• W2800107466 hasBestOaLocation W28001074661 @default.
• W2800107466 hasConcept C119599485 @default.
• W2800107466 hasConcept C127413603 @default.
• W2800107466 hasConcept C142462285 @default.
• W2800107466 hasConcept C144024400 @default.
• W2800107466 hasConcept C149923435 @default.
• W2800107466 hasConcept C159047783 @default.
• W2800107466 hasConcept C18903297 @default.
• W2800107466 hasConcept C205649164 @default.
• W2800107466 hasConcept C2779357621 @default.
• W2800107466 hasConcept C2908647359 @default.
• W2800107466 hasConcept C2993143319 @default.
• W2800107466 hasConcept C3013748606 @default.
• W2800107466 hasConcept C71924100 @default.
• W2800107466 hasConcept C761482 @default.
• W2800107466 hasConcept C83864248 @default.
• W2800107466 hasConcept C86803240 @default.
• W2800107466 hasConcept C91375879 @default.
• W2800107466 hasConceptScore W2800107466C119599485 @default.
• W2800107466 hasConceptScore W2800107466C127413603 @default.
• W2800107466 hasConceptScore W2800107466C142462285 @default.
• W2800107466 hasConceptScore W2800107466C144024400 @default.
• W2800107466 hasConceptScore W2800107466C149923435 @default.
• W2800107466 hasConceptScore W2800107466C159047783 @default.
• W2800107466 hasConceptScore W2800107466C18903297 @default.
• W2800107466 hasConceptScore W2800107466C205649164 @default.
• W2800107466 hasConceptScore W2800107466C2779357621 @default.
• W2800107466 hasConceptScore W2800107466C2908647359 @default.
• W2800107466 hasConceptScore W2800107466C2993143319 @default.
• W2800107466 hasConceptScore W2800107466C3013748606 @default.
• W2800107466 hasConceptScore W2800107466C71924100 @default.
• W2800107466 hasConceptScore W2800107466C761482 @default.
• W2800107466 hasConceptScore W2800107466C83864248 @default.
• W2800107466 hasConceptScore W2800107466C86803240 @default.
• W2800107466 hasConceptScore W2800107466C91375879 @default.
• W2800107466 hasFunder F4320332753 @default.
• W2800107466 hasIssue "4" @default.
• W2800107466 hasLocation W28001074661 @default.
• W2800107466 hasLocation W28001074662 @default.
• W2800107466 hasLocation W28001074663 @default.
• W2800107466 hasLocation W28001074664 @default.
• W2800107466 hasLocation W28001074665 @default.
• W2800107466 hasOpenAccess W2800107466 @default.
• W2800107466 hasPrimaryLocation W28001074661 @default.
• W2800107466 hasRelatedWork W1632477623 @default.
• W2800107466 hasRelatedWork W2006512534 @default.
• W2800107466 hasRelatedWork W2042312078 @default.
• W2800107466 hasRelatedWork W2165791755 @default.
• W2800107466 hasRelatedWork W2256186582 @default.
• W2800107466 hasRelatedWork W2603057875 @default.
• W2800107466 hasRelatedWork W2911784407 @default.
• W2800107466 hasRelatedWork W4236200878 @default.
• W2800107466 hasRelatedWork W4298058916 @default.

• next