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• W2800158088 abstract "Abstract Background Needleless transcutaneous electroacupuncture ( TEA ) improves nausea and myoelectrical activity in diabetic gastroparesis ( GP ). Synchronized TEA ( STEA ), which combines synchronized breathing with TEA , is more potent than TEA in enhancing vagal activity in healthy subjects. Aims To investigate whether STEA improves symptoms, electrogastrogram ( EGG ) and vagal activity in idiopathic gastroparesis ( IGP ). Methods Eighteen IGP subjects underwent 2 randomized visits (sham at non‐acupoints or real STEA at acupoints) consisted of a 30‐minute baseline, an Ensure challenge to provoke nausea, followed by 60‐minute treatment with sham or real STEA , and 15‐minute observation period. Severity of nausea, EGG , and vagal activity (based on electrocardiogram and serum Pancreatic Polypeptide, PP ) were recorded. Results In sham or STEA , the nausea scores of 2.7 ± 0.5 and 1.9 ± 0.5 at fasting baseline, respectively, increased to 5.9 ± 0.4 and 5.8 ± 0.3 during Ensure test ( P < .05, vs baseline), subsequently reduced to 3.4 ± 0.6 with sham or 3.6 ± 0.6 with STEA , respectively ( P < .05, vs Ensure period). Experiments with sham and STEA started with similar % of normal waves on EGG (66.4 ± 3.9 and 61.8 ± 3.0, respectively); decreased to 63. 5 ± 4.1 and 58.2 ± 2.8 during the Ensure test. After STEA , there was ~24% increase in % of normal waves, significantly different from the sham (6.0%) ( P < .01). In sham or STEA , vagal activity was identical at baseline and after the Ensure. STEA induced a 3‐fold increase in vagal activity compared with sham ( P < .01). Ensure increased serum PP levels, and both treatments decreased the PP Conclusions In IGP , STEA is not superior to Sham in decreasing nausea, but is more effective in improving gastric dysrhythmia." @default.
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• W2800158088 date "2018-05-10" @default.
• W2800158088 modified "2023-09-26" @default.
• W2800158088 title "Efficacy of needleless transcutaneous electroacupuncture in synchronization with breathing for symptomatic idiopathic gastroparesis: A blinded and controlled acute treatment trial" @default.
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• W2800158088 doi "https://doi.org/10.1111/nmo.13361" @default.
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