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- W2800183740 abstract "Abstract Objective: Ectopic Cushing's syndrome secondary to thymic carcinoid is a rare disorder that may be difficult to diagnose and manage. Methods: We describe a case of severe Cushing's syndrome secondary to a large adrenocorticotropic hormone (ACTH) producing thymic carcinoid in a patient with history of primary hyperaldosteronism. Results: A 43-year-old female with a 20 year history of an aldosterone-secreting adrenocortical adenoma status post right adrenalectomy presented with acute onset of proximal muscle weakness, swelling, facial hirsutism, and severe hypokalemia. Ectopic Cushing's Syndrome was suspected based on the sudden symptom onset and markedly elevated 24-hr urine cortisol and ACTH levels. MRI revealed an empty pituitary sella and a large (7.3 cm) mediastinal mass visible on chest CT. The mass was resected by video-assisted thoracoscopic surgery, resulting in resolution of symptoms and cortisol levels. Pathology assessment confirmed well-differentiated thymic carcinoid with positive ACT..." @default.
- W2800183740 created "2018-05-17" @default.
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- W2800183740 date "2018-05-01" @default.
- W2800183740 modified "2023-09-26" @default.
- W2800183740 title "THYMIC CARCINOID WITH ACTH-PRODUCING ECTOPIC CUSHING'S SYNDROME AND EMPTY SELLA." @default.
- W2800183740 doi "https://doi.org/10.4158/ep-2018-0045" @default.
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