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• W2800237011 endingPage "e13684" @default.
• W2800237011 startingPage "e13684" @default.
• W2800237011 abstract "High-intensity intermittent training (HIIT) has been shown to reduce the risk of chronic conditions including the development of type 2 diabetes mellitus (T2DM). Independently, a low vitamin D status has also been linked to the prevalence of T2DM. The aim of this study was to investigate if there was a synergistic metabolic effect of HIIT and vitamin D supplementation on glycemic control. A total of 20 male and female participants (age, 34 ± 9 year; BMI, 31.4 ± 2.8 kg·m-2 ) completed 6 weeks HIIT, and were randomized to ingest 100 μg·day-1 of vitamin D3 or placebo. Response to an oral glucose tolerance test (OGTT) was determined at baseline and at 72 h postintervention. Glucose tolerance was improved as a result of the HIIT intervention, shown through a reduction in glucose and insulin concentrations during the OGTT, accompanied by a decrease in glucose (829 ± 110 to 786 ± 139 mmol·h-1 ·L-1 ; P = 0.043) and insulin (8101 ± 4755-7024 ± 4489 mU·h-1 ·L-1 ; P = 0.049) area under the curve (AUC). Supplementation increased 25-hydroxyvitamin D3 concentration by 120% to a sufficiency status (P < 0.001). However, the consumption of vitamin D3 seemed to attenuate the glucose response during an OGTT. Triglyceride content was lowered following the intervention (P = 0.025). There was no effect of the intervention on insulin sensitivity (IS) indices: ISIMatsuda and HOMA-IR. Our findings demonstrate that HIIT improves glucose tolerance in nondiabetic overweight and obese adults; however vitamin D3 supplementation did not proffer any additional positive effects on the measured indices of metabolic health." @default.
• W2800237011 created "2018-05-17" @default.
• W2800237011 creator A5001420947 @default.
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• W2800237011 date "2018-04-30" @default.
• W2800237011 modified "2023-09-30" @default.
• W2800237011 title "The combined effect of high-intensity intermittent training and vitamin D supplementation on glycemic control in overweight and obese adults" @default.
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• W2800237011 doi "https://doi.org/10.14814/phy2.13684" @default.
• W2800237011 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5925425" @default.
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