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- W2800521311 abstract "This project designed to determined the effect of edible mushroom-Ag-Nps in combined with conventional antibiotics against selected multidrug biofilm forming patbiofilm producer bacteria were isolated and identified using routine cultural and biochemical tests from clinical specimen,in addition to that bacterial standard strains were used. Silver nanoparticle was prepared by using edible mushroom as bio-reductant. The biosynthesis of Ag-Nps was characterized by changing mushroom extract colorfrom clear yellow to brown and uv/visual spectrophotometer, electronic microscope.then, the Ag-Nps was tested against bacterial strains and biofilm producer bacteriausing diffusion method as antibacterial agents in combination with antibiotics. Biosynthesized Ag-Nps characterized by visual spectroscopy, Scannining Electronic Microscope (SEM) were ranged (5-50 nm) in size and Fourier Transform Infrared Spectroscopy (FTIR) in peak 430 cm-1 refers to proteins formation.Different volumes andconcentration of AgNps (20,30,and 50 µl )were tested against selected multi drug biofilm pathogens showed the Ag-NPs at concentration50 µl was the most efficient in the inhibition of bacterial growth. On the other hand, Those assessment of the consolidated impact were examined utilizing circle dissemination strategy against Methicillin Resists Staph aureus (MRSA), Eschershia coli, Pseudomonas aeruginosa andProtues mirabilis. Results recorded a synergetic effect of Ag-Nps -in association with resistant antibiotics.greater potential as antimicrobial compounds against pathogenic micro-organisms,and that they Combination ofnanoparticles withantibiotics inhibited effectivelyability to formbiofilm than antibiotics alone,from this we can conclude that Ag-NPs havemay be used in the remediation of infectious diseases,so Ag-NPswith antibiotics show maximum antibacterial activity,and so his may lead to developed of new pharmaceuticals therapeutic needs." @default.
- W2800521311 created "2018-05-17" @default.
- W2800521311 creator A5086367683 @default.
- W2800521311 date "2018-04-16" @default.
- W2800521311 modified "2023-09-27" @default.
- W2800521311 title "Combination Effect of Edible Mushroom – Sliver Nanoparticles and Antibioticsagainst selected Multidrug Biofilm Pathogens" @default.
- W2800521311 doi "https://doi.org/10.26452/ijrps.v9ispl1.1343" @default.
- W2800521311 hasPublicationYear "2018" @default.
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