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- W2800580461 endingPage "160" @default.
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- W2800580461 abstract "Morbidity and mortality from colorectal cancer (CRC) can be effectively reduced through early detection and prevention. To date, strategies for managing CRC risk have focused primarily on secondary prevention, through screening asymptomatic individuals for colorectal neoplasia. In the United States, implementation of screening among individuals age ≥50 has led to not only decreased CRC-related mortality but also reduced CRC incidence through colonoscopic removal of precancerous polyps. In contrast to screening's endpoint of early detection, the goal of primary prevention of CRC is to arrest and/or reverse colorectal carcinogenesis. Observational studies and randomized clinical trials continue to examine effects of specific pharmacologic agents (chemoprevention) and dietary interventions on development of advanced colorectal neoplasia. This review will present an overview of strategies for primary and secondary prevention of CRC, including endoscopic, pharmacologic, and dietary interventions." @default.
- W2800580461 created "2018-05-17" @default.
- W2800580461 creator A5038045975 @default.
- W2800580461 date "2018-05-01" @default.
- W2800580461 modified "2023-10-16" @default.
- W2800580461 title "Updates on Translational Research on Prevention of Polyps and Colorectal Cancer" @default.
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- W2800580461 doi "https://doi.org/10.1055/s-0037-1602235" @default.
- W2800580461 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5929882" @default.
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