Matches in SemOpenAlex for { <https://semopenalex.org/work/W2800632499> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2800632499 abstract "Urothelial carcinoma (UC) is one of the most frequent epithelial tumors worldwide.We aimed to investigate the protein expressions of caspase-8, p53, murine double minute 2 (mdm2), and p14ARF in nonmuscle UCs and to correlate the findings with clinicopathological characteristics.A total of 50 patients who had pTa and pT1 tumors were analyzed.The protein expressions of caspase-8, p53, mdm2, and p14ARF were analyzed by immunohistochemistry.Chi-square test was done using SPSS version 16.0 (SPSS, Inc., Chicago, IL, USA).Cytoplasmic caspase-8 expression was significantly higher in pT1 UCs while nuclear caspase-8 expression was significantly higher in pTa UCs (P = 0.005 and P = 0.011, respectively). Cytoplasmic caspase-8 expression was also higher in high-grade UCs (P = 0.035). The expression of p53, mdm2, and p14ARF was not also related with pathological stage or grade (P > 0.05 for all). The p14ARF expression was related with nuclear caspase-8 expression in most of the patients. Complete agreement among nonmuscle UCs for immunohistochemical expression of p14 and nuclear caspase-8 was seen in 41 cases, and the pairwise kappa agreement value was substantial (κ =0.614). The patients who had recurrence were positive for both p53 and mdm2 or either p53 or mdm2 (P = 0.025).These results suggested that the staining pattern of caspase-8 might be helpful for determining of the stages in nonmuscle UC. It was also showed that the expression status of p53 and mdm2 were related with the recurrence." @default.
- W2800632499 created "2018-05-17" @default.
- W2800632499 creator A5013713588 @default.
- W2800632499 creator A5023574326 @default.
- W2800632499 creator A5028778461 @default.
- W2800632499 creator A5039574778 @default.
- W2800632499 date "2018-01-01" @default.
- W2800632499 modified "2023-09-26" @default.
- W2800632499 title "The determination of stage in nonmuscle urothelial carcinoma: Staining pattern of caspase-8" @default.
- W2800632499 doi "https://doi.org/10.4103/ijpm.ijpm_161_17" @default.
- W2800632499 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29676355" @default.
- W2800632499 hasPublicationYear "2018" @default.
- W2800632499 type Work @default.
- W2800632499 sameAs 2800632499 @default.
- W2800632499 citedByCount "0" @default.
- W2800632499 crossrefType "journal-article" @default.
- W2800632499 hasAuthorship W2800632499A5013713588 @default.
- W2800632499 hasAuthorship W2800632499A5023574326 @default.
- W2800632499 hasAuthorship W2800632499A5028778461 @default.
- W2800632499 hasAuthorship W2800632499A5039574778 @default.
- W2800632499 hasBestOaLocation W28006324991 @default.
- W2800632499 hasConcept C121608353 @default.
- W2800632499 hasConcept C12519072 @default.
- W2800632499 hasConcept C126322002 @default.
- W2800632499 hasConcept C142724271 @default.
- W2800632499 hasConcept C146357865 @default.
- W2800632499 hasConcept C151730666 @default.
- W2800632499 hasConcept C190283241 @default.
- W2800632499 hasConcept C204232928 @default.
- W2800632499 hasConcept C207886595 @default.
- W2800632499 hasConcept C2776192174 @default.
- W2800632499 hasConcept C2776750431 @default.
- W2800632499 hasConcept C2778264664 @default.
- W2800632499 hasConcept C2779343474 @default.
- W2800632499 hasConcept C31573885 @default.
- W2800632499 hasConcept C55493867 @default.
- W2800632499 hasConcept C555283112 @default.
- W2800632499 hasConcept C71924100 @default.
- W2800632499 hasConcept C74864618 @default.
- W2800632499 hasConcept C86803240 @default.
- W2800632499 hasConceptScore W2800632499C121608353 @default.
- W2800632499 hasConceptScore W2800632499C12519072 @default.
- W2800632499 hasConceptScore W2800632499C126322002 @default.
- W2800632499 hasConceptScore W2800632499C142724271 @default.
- W2800632499 hasConceptScore W2800632499C146357865 @default.
- W2800632499 hasConceptScore W2800632499C151730666 @default.
- W2800632499 hasConceptScore W2800632499C190283241 @default.
- W2800632499 hasConceptScore W2800632499C204232928 @default.
- W2800632499 hasConceptScore W2800632499C207886595 @default.
- W2800632499 hasConceptScore W2800632499C2776192174 @default.
- W2800632499 hasConceptScore W2800632499C2776750431 @default.
- W2800632499 hasConceptScore W2800632499C2778264664 @default.
- W2800632499 hasConceptScore W2800632499C2779343474 @default.
- W2800632499 hasConceptScore W2800632499C31573885 @default.
- W2800632499 hasConceptScore W2800632499C55493867 @default.
- W2800632499 hasConceptScore W2800632499C555283112 @default.
- W2800632499 hasConceptScore W2800632499C71924100 @default.
- W2800632499 hasConceptScore W2800632499C74864618 @default.
- W2800632499 hasConceptScore W2800632499C86803240 @default.
- W2800632499 hasLocation W28006324991 @default.
- W2800632499 hasLocation W28006324992 @default.
- W2800632499 hasLocation W28006324993 @default.
- W2800632499 hasOpenAccess W2800632499 @default.
- W2800632499 hasPrimaryLocation W28006324991 @default.
- W2800632499 hasRelatedWork W1520462922 @default.
- W2800632499 hasRelatedWork W1596289103 @default.
- W2800632499 hasRelatedWork W1979857730 @default.
- W2800632499 hasRelatedWork W2002546504 @default.
- W2800632499 hasRelatedWork W2012245666 @default.
- W2800632499 hasRelatedWork W2048923236 @default.
- W2800632499 hasRelatedWork W2080928706 @default.
- W2800632499 hasRelatedWork W2083343708 @default.
- W2800632499 hasRelatedWork W2151924640 @default.
- W2800632499 hasRelatedWork W2329599493 @default.
- W2800632499 hasRelatedWork W2345856129 @default.
- W2800632499 hasRelatedWork W2349644819 @default.
- W2800632499 hasRelatedWork W2378979417 @default.
- W2800632499 hasRelatedWork W2383949268 @default.
- W2800632499 hasRelatedWork W2385425844 @default.
- W2800632499 hasRelatedWork W2461861870 @default.
- W2800632499 hasRelatedWork W2747066422 @default.
- W2800632499 hasRelatedWork W2978427021 @default.
- W2800632499 hasRelatedWork W3030348039 @default.
- W2800632499 hasRelatedWork W2340421354 @default.
- W2800632499 isParatext "false" @default.
- W2800632499 isRetracted "false" @default.
- W2800632499 magId "2800632499" @default.
- W2800632499 workType "article" @default.