FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2800690473> ?p ?o ?g. }

• W2800690473 endingPage "9" @default.
• W2800690473 startingPage "1" @default.
• W2800690473 abstract "Studying the profile of micro RNAs (miRs) elucidated the highest expressed miRs in hepatic differentiation. In this study, we investigated to clarify the role of three embryonic overexpressed miRs (miR-106a, miR-574-3p and miR-451) during hepatic differentiation of human umbilical cord derived mesenchymal stem cells (UC-MSCs). We furthermore, aimed to explore whether overexpression of any of these miRs alone is sufficient to induce the differentiation of the UC-MSCs into hepatocyte-like cells. UC-MSCs were transfected either alone or together with miR-106a, miR-574-3p and miR-451 and their potential hepatic differentiation and alteration in gene expression profile, morphological changes and albumin secretion ability were investigated. We found that up-regulation of any of these three miRs alone cannot induce expression of all hepatic specific genes. Transfection of each miR alone, led to Sox17, FoxA2 expression that are related to initiation step of hepatic differentiation. However, concurrent ectopic overexpression of three miRs together can induce UC-MSCs differentiation into functionally mature hepatocytes. These results show that miRs have the capability to directly convert UC-MSCs to a hepatocyte phenotype in vitro." @default.
• W2800690473 created "2018-05-17" @default.
• W2800690473 creator A5004397127 @default.
• W2800690473 creator A5012308334 @default.
• W2800690473 creator A5037977360 @default.
• W2800690473 creator A5042429279 @default.
• W2800690473 creator A5074975866 @default.
• W2800690473 creator A5084556010 @default.
• W2800690473 date "2018-08-01" @default.
• W2800690473 modified "2023-09-26" @default.
• W2800690473 title "Differentiation of umbilical cord derived mesenchymal stem cells to hepatocyte cells by transfection of miR-106a, miR-574-3p, and miR-451" @default.
• W2800690473 cites W1542326554 @default.
• W2800690473 cites W1844747712 @default.
• W2800690473 cites W1976918297 @default.
• W2800690473 cites W1982193071 @default.
• W2800690473 cites W1987315409 @default.
• W2800690473 cites W1997424007 @default.
• W2800690473 cites W2015311527 @default.
• W2800690473 cites W2025912383 @default.
• W2800690473 cites W2030390561 @default.
• W2800690473 cites W2031853603 @default.
• W2800690473 cites W2043058521 @default.
• W2800690473 cites W2045574035 @default.
• W2800690473 cites W2056011373 @default.
• W2800690473 cites W2058553784 @default.
• W2800690473 cites W2062290953 @default.
• W2800690473 cites W2072359769 @default.
• W2800690473 cites W2078822056 @default.
• W2800690473 cites W2081875195 @default.
• W2800690473 cites W2082496751 @default.
• W2800690473 cites W2085336665 @default.
• W2800690473 cites W2089154676 @default.
• W2800690473 cites W2091645107 @default.
• W2800690473 cites W2105051867 @default.
• W2800690473 cites W2106586369 @default.
• W2800690473 cites W2123389370 @default.
• W2800690473 cites W2125987139 @default.
• W2800690473 cites W2133478942 @default.
• W2800690473 cites W2139055053 @default.
• W2800690473 cites W2152455258 @default.
• W2800690473 cites W2161936179 @default.
• W2800690473 cites W2164083281 @default.
• W2800690473 cites W2529911568 @default.
• W2800690473 cites W2570431313 @default.
• W2800690473 cites W2589094119 @default.
• W2800690473 cites W2732949505 @default.
• W2800690473 cites W2770162053 @default.
• W2800690473 cites W4232584760 @default.
• W2800690473 doi "https://doi.org/10.1016/j.gene.2018.05.028" @default.
• W2800690473 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29763649" @default.
• W2800690473 hasPublicationYear "2018" @default.
• W2800690473 type Work @default.
• W2800690473 sameAs 2800690473 @default.
• W2800690473 citedByCount "18" @default.
• W2800690473 countsByYear W28006904732019 @default.
• W2800690473 countsByYear W28006904732020 @default.
• W2800690473 countsByYear W28006904732021 @default.
• W2800690473 countsByYear W28006904732022 @default.
• W2800690473 countsByYear W28006904732023 @default.
• W2800690473 crossrefType "journal-article" @default.
• W2800690473 hasAuthorship W2800690473A5004397127 @default.
• W2800690473 hasAuthorship W2800690473A5012308334 @default.
• W2800690473 hasAuthorship W2800690473A5037977360 @default.
• W2800690473 hasAuthorship W2800690473A5042429279 @default.
• W2800690473 hasAuthorship W2800690473A5074975866 @default.
• W2800690473 hasAuthorship W2800690473A5084556010 @default.
• W2800690473 hasConcept C104317684 @default.
• W2800690473 hasConcept C145059251 @default.
• W2800690473 hasConcept C145103041 @default.
• W2800690473 hasConcept C148397407 @default.
• W2800690473 hasConcept C148738053 @default.
• W2800690473 hasConcept C153911025 @default.
• W2800690473 hasConcept C198826908 @default.
• W2800690473 hasConcept C202751555 @default.
• W2800690473 hasConcept C203014093 @default.
• W2800690473 hasConcept C2776200302 @default.
• W2800690473 hasConcept C2776955114 @default.
• W2800690473 hasConcept C28328180 @default.
• W2800690473 hasConcept C54009773 @default.
• W2800690473 hasConcept C54355233 @default.
• W2800690473 hasConcept C86803240 @default.
• W2800690473 hasConcept C95444343 @default.
• W2800690473 hasConcept C97037327 @default.
• W2800690473 hasConceptScore W2800690473C104317684 @default.
• W2800690473 hasConceptScore W2800690473C145059251 @default.
• W2800690473 hasConceptScore W2800690473C145103041 @default.
• W2800690473 hasConceptScore W2800690473C148397407 @default.
• W2800690473 hasConceptScore W2800690473C148738053 @default.
• W2800690473 hasConceptScore W2800690473C153911025 @default.
• W2800690473 hasConceptScore W2800690473C198826908 @default.
• W2800690473 hasConceptScore W2800690473C202751555 @default.
• W2800690473 hasConceptScore W2800690473C203014093 @default.
• W2800690473 hasConceptScore W2800690473C2776200302 @default.
• W2800690473 hasConceptScore W2800690473C2776955114 @default.
• W2800690473 hasConceptScore W2800690473C28328180 @default.
• W2800690473 hasConceptScore W2800690473C54009773 @default.
• W2800690473 hasConceptScore W2800690473C54355233 @default.
• W2800690473 hasConceptScore W2800690473C86803240 @default.

• next