FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2800699997> ?p ?o ?g. }

• W2800699997 endingPage "177" @default.
• W2800699997 startingPage "169" @default.
• W2800699997 abstract "Microcapsules fabricated using layer-by-layer self-assembly have unique properties, making them attractive for drug delivery applications. The technique has been improved, allowing the deposition of multiple layers of oppositely charged polyelectrolytes on spherical, colloidal templates. These templates can be decomposed by coating multiple layers, resulting in hollow shells. In this paper, we describe a novel drug delivery system for loading photosensitizer drugs into hollow multilayered microcapsules for photoprocess applications. Manganese carbonate particles were prepared by mixing NH4HCO3 and MnSO4 and performing consecutive polyelectrolyte adsorption processes onto these templates using poly-(sodium 4-styrene sulfonate) and poly-(allylamine hydrocholoride). A photosensitizer was also incorporated into the layers. Hollow spheres were fabricated by removing the cores in the acidic solution. The hollow, multilayered microcapsules were studied by scanning electron microscopy, steady-state, and time-resolved techniques. Their biological activity was evaluated in vitro with cancer cells using a conventional MTT assay. The synthesized CaCO3 microparticles were uniform, non-aggregated, and highly porous spheres. The phthalocyanine derivatives loaded in the microcapsules maintained their photophysical behaviour after encapsulation. The spectroscopic results presented here showed excellent photophysical behaviour of the studied drug. We observed a desirable increase in singlet oxygen production, which is favourable for the PDT protocol. Cell viability after treatment was determined and the proposed microcapsules caused 80% cell death compared to the control. The results demonstrate that photosensitizer adsorption into the CaCO3 microparticle voids together with the layer-by-layer assembly of biopolymers provide a method for the fabrication of biocompatible microcapsules for use as biomaterials." @default.
• W2800699997 created "2018-05-17" @default.
• W2800699997 creator A5008931981 @default.
• W2800699997 creator A5029538099 @default.
• W2800699997 creator A5074558889 @default.
• W2800699997 date "2018-06-01" @default.
• W2800699997 modified "2023-10-14" @default.
• W2800699997 title "Layer-by-layer hollow photosensitizer microcapsule design via a manganese carbonate hard template for photodynamic therapy in cells" @default.
• W2800699997 cites W1527326791 @default.
• W2800699997 cites W1629179716 @default.
• W2800699997 cites W1964019697 @default.
• W2800699997 cites W1964603841 @default.
• W2800699997 cites W1972320018 @default.
• W2800699997 cites W1975872618 @default.
• W2800699997 cites W1990486870 @default.
• W2800699997 cites W1995057402 @default.
• W2800699997 cites W2018155191 @default.
• W2800699997 cites W2021848398 @default.
• W2800699997 cites W2025178477 @default.
• W2800699997 cites W2026311937 @default.
• W2800699997 cites W2038493298 @default.
• W2800699997 cites W2041552752 @default.
• W2800699997 cites W2045238664 @default.
• W2800699997 cites W2048736491 @default.
• W2800699997 cites W2049174193 @default.
• W2800699997 cites W2050297071 @default.
• W2800699997 cites W2051782924 @default.
• W2800699997 cites W2052755837 @default.
• W2800699997 cites W2052888909 @default.
• W2800699997 cites W2070545569 @default.
• W2800699997 cites W2076206592 @default.
• W2800699997 cites W2076365919 @default.
• W2800699997 cites W2078871866 @default.
• W2800699997 cites W2090565388 @default.
• W2800699997 cites W2096575630 @default.
• W2800699997 cites W2142890875 @default.
• W2800699997 cites W2151734986 @default.
• W2800699997 cites W2158428798 @default.
• W2800699997 cites W2162007134 @default.
• W2800699997 cites W2162860023 @default.
• W2800699997 cites W2556416529 @default.
• W2800699997 cites W2580986754 @default.
• W2800699997 cites W2590840126 @default.
• W2800699997 cites W2617113565 @default.
• W2800699997 cites W2733667023 @default.
• W2800699997 cites W3104396838 @default.
• W2800699997 cites W4250743572 @default.
• W2800699997 doi "https://doi.org/10.1016/j.pdpdt.2018.04.011" @default.
• W2800699997 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29684688" @default.
• W2800699997 hasPublicationYear "2018" @default.
• W2800699997 type Work @default.
• W2800699997 sameAs 2800699997 @default.
• W2800699997 citedByCount "16" @default.
• W2800699997 countsByYear W28006999972019 @default.
• W2800699997 countsByYear W28006999972020 @default.
• W2800699997 countsByYear W28006999972021 @default.
• W2800699997 countsByYear W28006999972022 @default.
• W2800699997 countsByYear W28006999972023 @default.
• W2800699997 crossrefType "journal-article" @default.
• W2800699997 hasAuthorship W2800699997A5008931981 @default.
• W2800699997 hasAuthorship W2800699997A5029538099 @default.
• W2800699997 hasAuthorship W2800699997A5074558889 @default.
• W2800699997 hasConcept C127413603 @default.
• W2800699997 hasConcept C153356533 @default.
• W2800699997 hasConcept C155672457 @default.
• W2800699997 hasConcept C159985019 @default.
• W2800699997 hasConcept C171250308 @default.
• W2800699997 hasConcept C178790620 @default.
• W2800699997 hasConcept C185592680 @default.
• W2800699997 hasConcept C192562407 @default.
• W2800699997 hasConcept C26771246 @default.
• W2800699997 hasConcept C2777521759 @default.
• W2800699997 hasConcept C2779227376 @default.
• W2800699997 hasConcept C2779820397 @default.
• W2800699997 hasConcept C2781469039 @default.
• W2800699997 hasConcept C42360764 @default.
• W2800699997 hasConcept C521977710 @default.
• W2800699997 hasConcept C62960913 @default.
• W2800699997 hasConceptScore W2800699997C127413603 @default.
• W2800699997 hasConceptScore W2800699997C153356533 @default.
• W2800699997 hasConceptScore W2800699997C155672457 @default.
• W2800699997 hasConceptScore W2800699997C159985019 @default.
• W2800699997 hasConceptScore W2800699997C171250308 @default.
• W2800699997 hasConceptScore W2800699997C178790620 @default.
• W2800699997 hasConceptScore W2800699997C185592680 @default.
• W2800699997 hasConceptScore W2800699997C192562407 @default.
• W2800699997 hasConceptScore W2800699997C26771246 @default.
• W2800699997 hasConceptScore W2800699997C2777521759 @default.
• W2800699997 hasConceptScore W2800699997C2779227376 @default.
• W2800699997 hasConceptScore W2800699997C2779820397 @default.
• W2800699997 hasConceptScore W2800699997C2781469039 @default.
• W2800699997 hasConceptScore W2800699997C42360764 @default.
• W2800699997 hasConceptScore W2800699997C521977710 @default.
• W2800699997 hasConceptScore W2800699997C62960913 @default.
• W2800699997 hasFunder F4320320997 @default.
• W2800699997 hasFunder F4320321091 @default.
• W2800699997 hasFunder F4320322904 @default.
• W2800699997 hasLocation W28006999971 @default.

• next