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- W2800761649 abstract "Twelve new ent ‐labdane diterpenoids, hypofolins A – F ( 1 – 6 ) and hypofolins G – L ( 7a / 7b , 8a / 8b , and 9a / 9b ), were isolated from the roots of Hypoestes phyllostachya ‘Pink Splash’. Their structures were elucidated by extensive 1D‐ and 2D‐ NMR spectroscopic and HR ‐ MS data. The absolute configurations of 1 , 2 , 5 , and 7a / 7b were determined by single crystal X‐ray diffraction and ECD analysis, as well as chemical transformations. Compounds 7a / 7b , 8a / 8b , and 9a / 9b were isolated as three pairs of interconverting mixture of two isomers between ketone and hemiketal types. Compound 1 showed weak cytotoxicity against SMMC ‐7721 cell line with IC 50 value of 31.40 μ m ." @default.
- W2800761649 created "2018-05-17" @default.
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- W2800761649 date "2018-05-21" @default.
- W2800761649 modified "2023-10-18" @default.
- W2800761649 title "Hypofolins A - L,<i>ent</i>-Labdane Diterpenoids from the Roots of<i>Hypoestes phyllostachya</i>‘Pink Splash’" @default.
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- W2800761649 doi "https://doi.org/10.1002/cbdv.201800124" @default.
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