FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2800869405> ?p ?o ?g. }

• W2800869405 abstract "Background: The traditional Chinese medicine classic herbal formula Longdanxiegan decoction (LDXGD) is widely used for hypertensive patients in China. Objectives: This systematic review and meta-analysis aimed to evaluate the efficacy and safety of LDXGD for hypertension. Methods: PubMed, EMBASE, Cochrane Central Register of Controlled Trials, Chinese Biomedical Literature Database, Chinese Scientific Journal Database, Chinese National Knowledge Infrastructure, and Wanfang Database were searched up to February 7, 2017 for randomized control trials in treating hypertension. Results: Nine trials were identified. Compared with antihypertensive drugs, Longdanxiegan decoction plus antihypertensive drugs (LPAD) significantly improved systolic blood pressure (BP) (n = 138; MD = -4.82 mmHg; 95% CI: -7.89 to -1.76; P = 0.002), diastolic BP (n = 138; MD = -2.42 mmHg; 95% CI: -3.22 to -1.62; P < 0.00001), categorical BP (n = 509; RR: 1.26; 95% CI: 1.17 to 1.36; P < 0.00001), hypertension related symptoms (n = 509; RR: 1.31; 95% CI: 1.15 to 1.49; P < 0.0001), and heart rate (n = 138; MD = -2.40 bpm; 95% CI: -4.23 to -0.56; P = 0.01). Beneficial effects but no statistically significant reduction in total cholesterol (n = 138; MD = -0.11 mmol/l; 95% CI: -0.65 to 0.44; P = 0.71), or triglyceride (n = 138; MD = -0.20 mmol/l; 95% CI: -0.46 to 0.07; P = 0.14) was observed in LPAD. Compared with antihypertensive drugs, LDXGD used alone significantly improved systolic BP, diastolic BP and hypertension related symptoms. But there was no difference between LDXGD and antihypertensive drugs on categorical BP (n = 120; RR: 1.09; 95% CI: 0.96 to 1.23; P = 0.18). The safety of LDXGD were still unclear. Conclusions: Due to poor methodological quality of the included trials, as well as potential reporting bias, our review found no conclusive evidence for the effectiveness of LDXGD in treating hypertension. The potential beneficial effects and safety of LDXGD should be assessed in future properly designed trials." @default.
• W2800869405 created "2018-05-17" @default.
• W2800869405 creator A5004808990 @default.
• W2800869405 creator A5012655789 @default.
• W2800869405 creator A5014483195 @default.
• W2800869405 creator A5019740165 @default.
• W2800869405 creator A5056272829 @default.
• W2800869405 creator A5071037763 @default.
• W2800869405 creator A5071304644 @default.
• W2800869405 creator A5089549114 @default.
• W2800869405 date "2018-05-08" @default.
• W2800869405 modified "2023-10-02" @default.
• W2800869405 title "Therapeutic Efficacy and Safety of Traditional Chinese Medicine Classic Herbal Formula Longdanxiegan Decoction for Hypertension: A Systematic Review and Meta-Analysis" @default.
• W2800869405 cites W1885544947 @default.
• W2800869405 cites W1980799772 @default.
• W2800869405 cites W2015138657 @default.
• W2800869405 cites W2024056183 @default.
• W2800869405 cites W2042947022 @default.
• W2800869405 cites W2049103906 @default.
• W2800869405 cites W2060748452 @default.
• W2800869405 cites W2064656245 @default.
• W2800869405 cites W2077354260 @default.
• W2800869405 cites W2080184611 @default.
• W2800869405 cites W2103592227 @default.
• W2800869405 cites W2113807240 @default.
• W2800869405 cites W2119856318 @default.
• W2800869405 cites W2126125759 @default.
• W2800869405 cites W2134157683 @default.
• W2800869405 cites W2134833483 @default.
• W2800869405 cites W2191546937 @default.
• W2800869405 cites W2583071874 @default.
• W2800869405 cites W2590748550 @default.
• W2800869405 cites W2783605155 @default.
• W2800869405 cites W4236805817 @default.
• W2800869405 doi "https://doi.org/10.3389/fphar.2018.00466" @default.
• W2800869405 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5953326" @default.
• W2800869405 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29867474" @default.
• W2800869405 hasPublicationYear "2018" @default.
• W2800869405 type Work @default.
• W2800869405 sameAs 2800869405 @default.
• W2800869405 citedByCount "11" @default.
• W2800869405 countsByYear W28008694052019 @default.
• W2800869405 countsByYear W28008694052020 @default.
• W2800869405 countsByYear W28008694052021 @default.
• W2800869405 countsByYear W28008694052022 @default.
• W2800869405 countsByYear W28008694052023 @default.
• W2800869405 crossrefType "journal-article" @default.
• W2800869405 hasAuthorship W2800869405A5004808990 @default.
• W2800869405 hasAuthorship W2800869405A5012655789 @default.
• W2800869405 hasAuthorship W2800869405A5014483195 @default.
• W2800869405 hasAuthorship W2800869405A5019740165 @default.
• W2800869405 hasAuthorship W2800869405A5056272829 @default.
• W2800869405 hasAuthorship W2800869405A5071037763 @default.
• W2800869405 hasAuthorship W2800869405A5071304644 @default.
• W2800869405 hasAuthorship W2800869405A5089549114 @default.
• W2800869405 hasBestOaLocation W28008694051 @default.
• W2800869405 hasConcept C126322002 @default.
• W2800869405 hasConcept C142724271 @default.
• W2800869405 hasConcept C168563851 @default.
• W2800869405 hasConcept C188947578 @default.
• W2800869405 hasConcept C190409667 @default.
• W2800869405 hasConcept C204787440 @default.
• W2800869405 hasConcept C2778163477 @default.
• W2800869405 hasConcept C2778913445 @default.
• W2800869405 hasConcept C556039675 @default.
• W2800869405 hasConcept C71924100 @default.
• W2800869405 hasConcept C84393581 @default.
• W2800869405 hasConcept C95190672 @default.
• W2800869405 hasConceptScore W2800869405C126322002 @default.
• W2800869405 hasConceptScore W2800869405C142724271 @default.
• W2800869405 hasConceptScore W2800869405C168563851 @default.
• W2800869405 hasConceptScore W2800869405C188947578 @default.
• W2800869405 hasConceptScore W2800869405C190409667 @default.
• W2800869405 hasConceptScore W2800869405C204787440 @default.
• W2800869405 hasConceptScore W2800869405C2778163477 @default.
• W2800869405 hasConceptScore W2800869405C2778913445 @default.
• W2800869405 hasConceptScore W2800869405C556039675 @default.
• W2800869405 hasConceptScore W2800869405C71924100 @default.
• W2800869405 hasConceptScore W2800869405C84393581 @default.
• W2800869405 hasConceptScore W2800869405C95190672 @default.
• W2800869405 hasLocation W28008694051 @default.
• W2800869405 hasLocation W28008694052 @default.
• W2800869405 hasLocation W28008694053 @default.
• W2800869405 hasLocation W28008694054 @default.
• W2800869405 hasLocation W28008694055 @default.
• W2800869405 hasLocation W28008694056 @default.
• W2800869405 hasOpenAccess W2800869405 @default.
• W2800869405 hasPrimaryLocation W28008694051 @default.
• W2800869405 hasRelatedWork W2333810885 @default.
• W2800869405 hasRelatedWork W2358632500 @default.
• W2800869405 hasRelatedWork W2369685549 @default.
• W2800869405 hasRelatedWork W2378784336 @default.
• W2800869405 hasRelatedWork W2380147533 @default.
• W2800869405 hasRelatedWork W2387835455 @default.
• W2800869405 hasRelatedWork W2421103793 @default.
• W2800869405 hasRelatedWork W3020858038 @default.
• W2800869405 hasRelatedWork W3085751988 @default.
• W2800869405 hasRelatedWork W3209981836 @default.
• W2800869405 hasVolume "9" @default.
• W2800869405 isParatext "false" @default.

• next