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• W2800891187 abstract "Abstract Context Hypoglycemia, occurring after bariatric and other forms of upper gastrointestinal surgery, is increasingly encountered by clinical endocrinologists. The true frequency of this condition remains uncertain, due, in part, to differences in the diagnostic criteria and in the affected populations, as well as relative lack of patient and physician awareness and understanding of this condition. Postbariatric hypoglycemia can be severe and disabling for some patients, with neuroglycopenia (altered cognition, seizures, and loss of consciousness) leading to falls, motor vehicle accidents, and job and income loss. Moreover, repeated episodes of hypoglycemia can result in hypoglycemia unawareness, further impairing safety and requiring the assistance of others to treat hypoglycemia. Objective In this review, we summarize and integrate data from studies of patients affected by hypoglycemia after Roux-en-Y gastric bypass (RYGB) surgery, obtained from PubMed searches (1990 to 2017) and reference searches of relevant retrieved articles. Whereas hypoglycemia can also be observed after sleeve gastrectomy and fundoplication, this review is focused on post-RYGB, given the greater body of published clinical studies at present. Outcome Measures Data addressing specific aspects of diagnosis, pathophysiology, and treatment were reviewed by the authors; when not available, the authors have provided opinions based on clinical experience with this challenging condition. Conclusions Hypoglycemia, occurring after gastric bypass surgery, is challenging for patients and physicians alike. This review provides a systematic approach to diagnosis and treatment based on the underlying pathophysiology." @default.
• W2800891187 created "2018-05-17" @default.
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• W2800891187 creator A5034412938 @default.
• W2800891187 creator A5045366155 @default.
• W2800891187 date "2018-05-04" @default.
• W2800891187 modified "2023-10-18" @default.
• W2800891187 title "Hypoglycemia After Gastric Bypass Surgery: Current Concepts and Controversies" @default.
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• W2800891187 doi "https://doi.org/10.1210/jc.2018-00528" @default.
• W2800891187 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6692713" @default.
• W2800891187 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30101281" @default.
• W2800891187 hasPublicationYear "2018" @default.
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