FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2800898209> ?p ?o ?g. }

• W2800898209 endingPage "1337" @default.
• W2800898209 startingPage "1329" @default.
• W2800898209 abstract "Objective To investigate brain structural connectivity in relation to cognitive abilities and systemic damage in systemic lupus erythematosus (SLE). Methods Structural and diffusion MRI data were acquired from 47 patients with SLE. Brains were segmented into 85 cortical and subcortical regions and combined with whole brain tractography to generate structural connectomes using graph theory. Global cognitive abilities were assessed using a composite variable g, derived from the first principal component of three common clinical screening tests of neurological function. SLE damage ( LD) was measured using a composite of a validated SLE damage score and disease duration. Relationships between network connectivity metrics, cognitive ability and systemic damage were investigated. Hub nodes were identified. Multiple linear regression, adjusting for covariates, was employed to model the outcomes g and LD as a function of network metrics. Results The network measures of density (standardised ß = 0.266, p = 0.025) and strength (standardised ß = 0.317, p = 0.022) were independently related to cognitive abilities. Strength (standardised ß = –0.330, p = 0.048), mean shortest path length (standardised ß = 0.401, p = 0.020), global efficiency (standardised ß = –0.355, p = 0.041) and clustering coefficient (standardised ß = –0.378, p = 0.030) were independently related to systemic damage. Network metrics were not related to current disease activity. Conclusion Better cognitive abilities and more SLE damage are related to brain topological network properties in this sample of SLE patients, even those without neuropsychiatric involvement and after correcting for important covariates. These data show that connectomics might be useful for understanding and monitoring cognitive function and white matter damage in SLE." @default.
• W2800898209 created "2018-05-17" @default.
• W2800898209 creator A5004889443 @default.
• W2800898209 creator A5033515344 @default.
• W2800898209 creator A5034776089 @default.
• W2800898209 creator A5036667571 @default.
• W2800898209 creator A5059508606 @default.
• W2800898209 creator A5079425548 @default.
• W2800898209 date "2018-05-03" @default.
• W2800898209 modified "2023-09-24" @default.
• W2800898209 title "Cognitive function, disease burden and the structural connectome in systemic lupus erythematosus" @default.
• W2800898209 cites W1847168837 @default.
• W2800898209 cites W1999653836 @default.
• W2800898209 cites W1999887188 @default.
• W2800898209 cites W2007542020 @default.
• W2800898209 cites W2019093320 @default.
• W2800898209 cites W2033078279 @default.
• W2800898209 cites W2034510106 @default.
• W2800898209 cites W2054330426 @default.
• W2800898209 cites W2070527591 @default.
• W2800898209 cites W2080167041 @default.
• W2800898209 cites W2090668679 @default.
• W2800898209 cites W2091931051 @default.
• W2800898209 cites W2104312285 @default.
• W2800898209 cites W2108905161 @default.
• W2800898209 cites W2117029142 @default.
• W2800898209 cites W2120741776 @default.
• W2800898209 cites W2128349793 @default.
• W2800898209 cites W2136395604 @default.
• W2800898209 cites W2140621953 @default.
• W2800898209 cites W2154282155 @default.
• W2800898209 cites W2154658384 @default.
• W2800898209 cites W2158742097 @default.
• W2800898209 cites W2165758561 @default.
• W2800898209 cites W2167822639 @default.
• W2800898209 cites W2168146874 @default.
• W2800898209 cites W2283370759 @default.
• W2800898209 cites W2518933466 @default.
• W2800898209 cites W2526037441 @default.
• W2800898209 cites W2528659296 @default.
• W2800898209 cites W4295605475 @default.
• W2800898209 doi "https://doi.org/10.1177/0961203318772666" @default.
• W2800898209 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29722629" @default.
• W2800898209 hasPublicationYear "2018" @default.
• W2800898209 type Work @default.
• W2800898209 sameAs 2800898209 @default.
• W2800898209 citedByCount "12" @default.
• W2800898209 countsByYear W28008982092018 @default.
• W2800898209 countsByYear W28008982092019 @default.
• W2800898209 countsByYear W28008982092020 @default.
• W2800898209 countsByYear W28008982092021 @default.
• W2800898209 countsByYear W28008982092022 @default.
• W2800898209 countsByYear W28008982092023 @default.
• W2800898209 crossrefType "journal-article" @default.
• W2800898209 hasAuthorship W2800898209A5004889443 @default.
• W2800898209 hasAuthorship W2800898209A5033515344 @default.
• W2800898209 hasAuthorship W2800898209A5034776089 @default.
• W2800898209 hasAuthorship W2800898209A5036667571 @default.
• W2800898209 hasAuthorship W2800898209A5059508606 @default.
• W2800898209 hasAuthorship W2800898209A5079425548 @default.
• W2800898209 hasBestOaLocation W28008982092 @default.
• W2800898209 hasConcept C118552586 @default.
• W2800898209 hasConcept C126322002 @default.
• W2800898209 hasConcept C15744967 @default.
• W2800898209 hasConcept C169760540 @default.
• W2800898209 hasConcept C169900460 @default.
• W2800898209 hasConcept C185711340 @default.
• W2800898209 hasConcept C2779097318 @default.
• W2800898209 hasConcept C2779134260 @default.
• W2800898209 hasConcept C3018011982 @default.
• W2800898209 hasConcept C45715564 @default.
• W2800898209 hasConcept C71924100 @default.
• W2800898209 hasConceptScore W2800898209C118552586 @default.
• W2800898209 hasConceptScore W2800898209C126322002 @default.
• W2800898209 hasConceptScore W2800898209C15744967 @default.
• W2800898209 hasConceptScore W2800898209C169760540 @default.
• W2800898209 hasConceptScore W2800898209C169900460 @default.
• W2800898209 hasConceptScore W2800898209C185711340 @default.
• W2800898209 hasConceptScore W2800898209C2779097318 @default.
• W2800898209 hasConceptScore W2800898209C2779134260 @default.
• W2800898209 hasConceptScore W2800898209C3018011982 @default.
• W2800898209 hasConceptScore W2800898209C45715564 @default.
• W2800898209 hasConceptScore W2800898209C71924100 @default.
• W2800898209 hasFunder F4320330040 @default.
• W2800898209 hasIssue "8" @default.
• W2800898209 hasLocation W28008982091 @default.
• W2800898209 hasLocation W28008982092 @default.
• W2800898209 hasLocation W28008982093 @default.
• W2800898209 hasLocation W28008982094 @default.
• W2800898209 hasLocation W28008982095 @default.
• W2800898209 hasLocation W28008982096 @default.
• W2800898209 hasLocation W28008982097 @default.
• W2800898209 hasLocation W28008982098 @default.
• W2800898209 hasOpenAccess W2800898209 @default.
• W2800898209 hasPrimaryLocation W28008982091 @default.
• W2800898209 hasRelatedWork W1744057168 @default.
• W2800898209 hasRelatedWork W2550381304 @default.
• W2800898209 hasRelatedWork W2800898209 @default.

• next