Matches in SemOpenAlex for { <https://semopenalex.org/work/W2800979335> ?p ?o ?g. }
- W2800979335 endingPage "1371" @default.
- W2800979335 startingPage "1359" @default.
- W2800979335 abstract "Background Hypomagnesemia is associated with increased mortality and renal function decline in humans with chronic kidney disease (CKD). Magnesium is furthermore inversely associated with fibroblast growth factor 23 (FGF23), an important prognostic factor in CKD in cats. However, the prognostic significance of plasma magnesium in cats with CKD is unknown. Objectives To explore associations of plasma total magnesium concentration (tMg) with plasma FGF23 concentration, all‐cause mortality, and disease progression in cats with azotemic CKD. Animals Records of 174 client‐owned cats with IRIS stage 2‐4 CKD. Methods Cohort study. Cats with azotemic CKD were identified from the records of two London‐based first opinion practices (1999–2013). Possible associations of baseline plasma tMg with FGF23 concentration and risks of death and progression were explored using, respectively, linear, Cox, and logistic regression. Results Plasma tMg (reference interval, 1.73–2.57 mg/dL) was inversely associated with plasma FGF23 when controlling for plasma creatinine and phosphate concentrations (partial correlation coefficient, −0.50; P < .001). Hypomagnesemia was observed in 12% (20/174) of cats, and independently associated with increased risk of death (adjusted hazard ratio, 2.74; 95% confidence interval [CI], 1.35–5.55; P = .005). The unadjusted associations of hypermagnesemia (prevalence, 6%; 11/174 cats) with survival (hazard ratio, 2.88; 95% CI, 1.54–5.38; P = .001), and hypomagnesemia with progressive CKD (odds ratio, 17.7; 95% CI, 2.04–154; P = .009) lost significance in multivariable analysis. Conclusions and Clinical Importance Hypomagnesemia was associated with higher plasma FGF23 concentrations and increased risk of death. Measurement of plasma tMg augments prognostic information in cats with CKD, but whether these observations are associations or causations warrants further investigation." @default.
- W2800979335 created "2018-05-17" @default.
- W2800979335 creator A5002937877 @default.
- W2800979335 creator A5055053952 @default.
- W2800979335 creator A5062854708 @default.
- W2800979335 creator A5078023429 @default.
- W2800979335 date "2018-04-27" @default.
- W2800979335 modified "2023-10-17" @default.
- W2800979335 title "Prognostic importance of plasma total magnesium in a cohort of cats with azotemic chronic kidney disease" @default.
- W2800979335 cites W1514741969 @default.
- W2800979335 cites W1573031619 @default.
- W2800979335 cites W1717754754 @default.
- W2800979335 cites W1822359430 @default.
- W2800979335 cites W1869176887 @default.
- W2800979335 cites W1905763298 @default.
- W2800979335 cites W1964651007 @default.
- W2800979335 cites W1972016934 @default.
- W2800979335 cites W1979597056 @default.
- W2800979335 cites W1979764452 @default.
- W2800979335 cites W1982605543 @default.
- W2800979335 cites W1986009662 @default.
- W2800979335 cites W1994519747 @default.
- W2800979335 cites W1998700853 @default.
- W2800979335 cites W1999112251 @default.
- W2800979335 cites W2000936082 @default.
- W2800979335 cites W2002494594 @default.
- W2800979335 cites W2019229162 @default.
- W2800979335 cites W2020095682 @default.
- W2800979335 cites W2023799462 @default.
- W2800979335 cites W2040123698 @default.
- W2800979335 cites W2047610525 @default.
- W2800979335 cites W2049581527 @default.
- W2800979335 cites W2049665187 @default.
- W2800979335 cites W2049727846 @default.
- W2800979335 cites W2054860475 @default.
- W2800979335 cites W2056514966 @default.
- W2800979335 cites W2057195809 @default.
- W2800979335 cites W2057313488 @default.
- W2800979335 cites W2058338941 @default.
- W2800979335 cites W2061557764 @default.
- W2800979335 cites W2062933384 @default.
- W2800979335 cites W2065443972 @default.
- W2800979335 cites W2066432245 @default.
- W2800979335 cites W2068173890 @default.
- W2800979335 cites W2071314187 @default.
- W2800979335 cites W2076641047 @default.
- W2800979335 cites W2077127226 @default.
- W2800979335 cites W2080169592 @default.
- W2800979335 cites W2082032921 @default.
- W2800979335 cites W2094551185 @default.
- W2800979335 cites W2097860515 @default.
- W2800979335 cites W2103016161 @default.
- W2800979335 cites W2111190876 @default.
- W2800979335 cites W2111816506 @default.
- W2800979335 cites W2113835727 @default.
- W2800979335 cites W2114682576 @default.
- W2800979335 cites W2115616090 @default.
- W2800979335 cites W2118687701 @default.
- W2800979335 cites W2122317595 @default.
- W2800979335 cites W2148382170 @default.
- W2800979335 cites W2156734882 @default.
- W2800979335 cites W2157897651 @default.
- W2800979335 cites W2159404905 @default.
- W2800979335 cites W2166670562 @default.
- W2800979335 cites W2167995070 @default.
- W2800979335 cites W2169669025 @default.
- W2800979335 cites W2172159264 @default.
- W2800979335 cites W2209794562 @default.
- W2800979335 cites W2224283588 @default.
- W2800979335 cites W2337187730 @default.
- W2800979335 cites W2484758046 @default.
- W2800979335 cites W2523748609 @default.
- W2800979335 cites W2523847757 @default.
- W2800979335 cites W2562981088 @default.
- W2800979335 cites W2741293692 @default.
- W2800979335 cites W2911414492 @default.
- W2800979335 cites W4206100856 @default.
- W2800979335 cites W4254714547 @default.
- W2800979335 doi "https://doi.org/10.1111/jvim.15141" @default.
- W2800979335 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6060321" @default.
- W2800979335 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29704284" @default.
- W2800979335 hasPublicationYear "2018" @default.
- W2800979335 type Work @default.
- W2800979335 sameAs 2800979335 @default.
- W2800979335 citedByCount "18" @default.
- W2800979335 countsByYear W28009793352018 @default.
- W2800979335 countsByYear W28009793352019 @default.
- W2800979335 countsByYear W28009793352020 @default.
- W2800979335 countsByYear W28009793352021 @default.
- W2800979335 countsByYear W28009793352022 @default.
- W2800979335 countsByYear W28009793352023 @default.
- W2800979335 crossrefType "journal-article" @default.
- W2800979335 hasAuthorship W2800979335A5002937877 @default.
- W2800979335 hasAuthorship W2800979335A5055053952 @default.
- W2800979335 hasAuthorship W2800979335A5062854708 @default.
- W2800979335 hasAuthorship W2800979335A5078023429 @default.
- W2800979335 hasBestOaLocation W28009793351 @default.
- W2800979335 hasConcept C114276007 @default.