FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2800988908> ?p ?o ?g. }

• W2800988908 endingPage "145" @default.
• W2800988908 startingPage "132" @default.
• W2800988908 abstract "Sex differences in methamphetamine (MA) abuse and consequences of MA have been reported with females showing an increased addiction phenotype and withdrawal symptoms. One mechanism through which these effects might occur is via sex-specific alterations in the hypothalamic–pituitary–adrenal (HPA) axis and its associated brain regions. In this study, mice were administered MA (5 mg/kg) or saline for 10 consecutive days. During early withdrawal, anxiety-like behaviors were assessed in the open field, light/dark box, and elevated plus maze. At ten days of withdrawal, mice were injected with a final dose of MA (5 mg/kg) or saline. Chronic MA did not alter anxiety-like behaviors or corticosterone responses to a final dose of MA, although females showed elevated corticosterone responses compared to males. Chronic MA attenuated final MA-induced c-Fos in both sexes in the paraventricular hypothalamus (PVH), bed nucleus of the stria terminalis (BNST), cingulate cortex, central and basolateral amygdala. In CA1 and CA3 hippocampal areas, c-Fos attenuation by chronic MA occurred only in females. Within the PVH, final MA injection increased c-Fos to a greater extent in females compared to males regardless of prior MA exposure. Dual-labeling of c-Fos with glucocorticoid receptor revealed a specific attenuation of neural activation within this cell type in the PVH, central and basolateral amygdala, and BNST. Together these findings demonstrate that chronic MA can suppress subsequent activation of HPA axis-associated brain regions and cell phenotypes. Further, in select regions this reduction is sex-specific. These changes may contribute to reported sex differences in MA abuse patterns." @default.
• W2800988908 created "2018-05-17" @default.
• W2800988908 creator A5022552663 @default.
• W2800988908 creator A5060224933 @default.
• W2800988908 creator A5061871956 @default.
• W2800988908 creator A5063074821 @default.
• W2800988908 creator A5079701180 @default.
• W2800988908 date "2018-06-01" @default.
• W2800988908 modified "2023-09-25" @default.
• W2800988908 title "Chronic Methamphetamine Exposure Attenuates Neural Activation in Hypothalamic–Pituitary–Adrenal Axis-Associated Brain Regions in a Sex-specific Manner" @default.
• W2800988908 cites W1536700299 @default.
• W2800988908 cites W1547358456 @default.
• W2800988908 cites W1548840547 @default.
• W2800988908 cites W1802874803 @default.
• W2800988908 cites W1812195397 @default.
• W2800988908 cites W1919000277 @default.
• W2800988908 cites W1944819460 @default.
• W2800988908 cites W1964160578 @default.
• W2800988908 cites W1966544510 @default.
• W2800988908 cites W1969909017 @default.
• W2800988908 cites W1979176326 @default.
• W2800988908 cites W1984785346 @default.
• W2800988908 cites W1986126435 @default.
• W2800988908 cites W1988102641 @default.
• W2800988908 cites W1989189858 @default.
• W2800988908 cites W1991170680 @default.
• W2800988908 cites W1996700127 @default.
• W2800988908 cites W1997596082 @default.
• W2800988908 cites W1998478270 @default.
• W2800988908 cites W2005615207 @default.
• W2800988908 cites W2007859086 @default.
• W2800988908 cites W2012438450 @default.
• W2800988908 cites W2014135566 @default.
• W2800988908 cites W2015775297 @default.
• W2800988908 cites W2025047921 @default.
• W2800988908 cites W2025711068 @default.
• W2800988908 cites W2028604638 @default.
• W2800988908 cites W2035258392 @default.
• W2800988908 cites W2035768743 @default.
• W2800988908 cites W2037417281 @default.
• W2800988908 cites W2041310506 @default.
• W2800988908 cites W2047712286 @default.
• W2800988908 cites W2047918052 @default.
• W2800988908 cites W2056302677 @default.
• W2800988908 cites W2058332830 @default.
• W2800988908 cites W2063067302 @default.
• W2800988908 cites W2063912965 @default.
• W2800988908 cites W2064624191 @default.
• W2800988908 cites W2066497867 @default.
• W2800988908 cites W2068376740 @default.
• W2800988908 cites W2074805425 @default.
• W2800988908 cites W2079890392 @default.
• W2800988908 cites W2080080874 @default.
• W2800988908 cites W2084137319 @default.
• W2800988908 cites W2084236418 @default.
• W2800988908 cites W2084255057 @default.
• W2800988908 cites W2085864665 @default.
• W2800988908 cites W2088343365 @default.
• W2800988908 cites W2088566452 @default.
• W2800988908 cites W2089966634 @default.
• W2800988908 cites W2089987450 @default.
• W2800988908 cites W2092614399 @default.
• W2800988908 cites W2094915083 @default.
• W2800988908 cites W2113167245 @default.
• W2800988908 cites W2115117609 @default.
• W2800988908 cites W2121807100 @default.
• W2800988908 cites W2138993052 @default.
• W2800988908 cites W2146644658 @default.
• W2800988908 cites W2159040523 @default.
• W2800988908 cites W2171268779 @default.
• W2800988908 cites W2277265972 @default.
• W2800988908 cites W2328224146 @default.
• W2800988908 cites W239922313 @default.
• W2800988908 cites W2413515606 @default.
• W2800988908 cites W2603984492 @default.
• W2800988908 cites W2607062688 @default.
• W2800988908 cites W2748566999 @default.
• W2800988908 cites W2758022181 @default.
• W2800988908 cites W2769601075 @default.
• W2800988908 cites W2774077521 @default.
• W2800988908 doi "https://doi.org/10.1016/j.neuroscience.2018.04.010" @default.
• W2800988908 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29679646" @default.
• W2800988908 hasPublicationYear "2018" @default.
• W2800988908 type Work @default.
• W2800988908 sameAs 2800988908 @default.
• W2800988908 citedByCount "10" @default.
• W2800988908 countsByYear W28009889082019 @default.
• W2800988908 countsByYear W28009889082020 @default.
• W2800988908 countsByYear W28009889082021 @default.
• W2800988908 countsByYear W28009889082022 @default.
• W2800988908 countsByYear W28009889082023 @default.
• W2800988908 crossrefType "journal-article" @default.
• W2800988908 hasAuthorship W2800988908A5022552663 @default.
• W2800988908 hasAuthorship W2800988908A5060224933 @default.
• W2800988908 hasAuthorship W2800988908A5061871956 @default.
• W2800988908 hasAuthorship W2800988908A5063074821 @default.
• W2800988908 hasAuthorship W2800988908A5079701180 @default.
• W2800988908 hasConcept C118552586 @default.

• next